Results 51 to 60 of about 28,072 (230)

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

Quantitative hematoma heterogeneity associated with hematoma growth in patients with early intracerebral hemorrhage

Frontiers in Neurology, 2022
BackgroundEarly hematoma growth is associated with poor functional outcomes in patients with intracerebral hemorrhage (ICH). We aimed to explore whether quantitative hematoma heterogeneity in non-contrast computed tomography (NCCT) can predict early ...
Mingpei Zhao, Wei Huang, Shuna Huang, Fuxin Lin, Fuxin Lin, Fuxin Lin, Qiu He, Yan Zheng, Zhuyu Gao, Lveming Cai, Gengzhao Ye, Renlong Chen, Siying Wu, Siying Wu, Wenhua Fang, Wenhua Fang, Dengliang Wang, Dengliang Wang, Yuanxiang Lin, Yuanxiang Lin, Dezhi Kang, Dezhi Kang, Dezhi Kang, Lianghong Yu, Lianghong Yu   +24 more
doaj   +1 more source

Subdural Hematoma in Grave’s Disease Induced Thrombocytopenia. [PDF]

, 2013
Subdural hematoma (SDH) usually occurs secondary to trauma, in bleeding disorders it may occur spontaneously. It is a rare complication of immune thrombocytopenia.
Chandek, S, Diwan, S, Kakani, A, Kumar, S, Nitey, PO   +4 more
core   +1 more source

Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial [PDF]

, 2018
Objective We present the statistical analysis plan of a prespecified Tranexamic Acid for Hyperacute Primary Intracerebral Haemorrhage (TICH)-2 sub-study aiming to investigate, if tranexamic acid has a different effect in intracerebral haemorrhage ...
A Ederies, A Giudice Del, A Meretoja, AD Oxman, AJ Vickers, AJ Vickers, AR Localio, AS Lord, BC Kahan, BC Kahan, C Delcourt, C Ovesen, Christian Gluud, Christian Ovesen, Crash-2 trial collaborators, D Dowlatshahi, D Rodriguez-Luna, DW Kang, FZ Du, H Hallevi, Hanne Christensen, J Witsch, Janus Christian Jakobsen, JC Jakobsen, K Flaherty, Katie Flaherty, L Liu, MB Maas, MT Poon, N Sprigg, N Sprigg, Nikola Sprigg, Philip M. Bath, R Leira, R Wada, Rob A. Dineen, RS Menon, SA Mayer, SA Mayer, SF Assmann, SM Davis, ST Brookes, T Steiner, Thorsten Steiner, TJ Moullaali, Zhe Law, ZK Law   +46 more
core   +5 more sources

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

The analysis of initial cranial CT of early hematoma enlargement in spontaneous intracerebral hemorrhage

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To investigate the predictive effect of initial cranial CT on early hematoma enlargement in spontaneous intracerebral hemorrhage. Methods Three hundred patients with spontaneous intracerebral hemorrhage within 6 hours after onset were studied ...
Yu⁃zhang BEI, Ben⁃yang CHEN, Hao⁃bo QI, Zheng⁃ping ZHOU, Yu⁃bo LI   +4 more
doaj  

Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage. [PDF]

, 2017
BACKGROUND: Injury to cells adjacent to an intracerebral hemorrhage (ICH) is likely mediated at least in part by toxins released from the hematoma that initiate complex and interacting injury cascades.
Chen-Roetling, Jing, Regan, Raymond F.
core   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

Volume and functional outcome of intracerebral hemorrhage according to oral anticoagulant type [PDF]

, 2015
Objective: To compare intracerebral hemorrhage (ICH) volume and clinical outcome of non–vitamin K oral anticoagulants (NOAC)–associated ICH to warfarin-associated ICH.
Al-Shahi Salman, R, Ambler, G, Brown, MM, Charidimou, A, Cohen, H, Jaeger, HR, Lip, GYH, Shakeshaft, C, Werring, DJ, White, M, Wilson, D, Yousry, T   +11 more
core   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source