Results 71 to 80 of about 6,010,235 (261)

Pre-transplant MRD negativity predicts favorable outcomes of CAR-T therapy followed by haploidentical HSCT for relapsed/refractory acute lymphoblastic leukemia: a multi-center retrospective study

Journal of Hematology & Oncology, 2020
Background Consolidative allogeneic hematopoietic stem cell transplantation is a controversial option for patients with relapsed/refractory acute lymphoblastic leukemia after chimeric antigen receptor T cell (CAR-T) therapy.
Houli Zhao, Jieping Wei, Guoqing Wei, Yi Luo, Jimin Shi, Qu Cui, Mingfeng Zhao, Aibin Liang, Qing Zhang, Jianmin Yang, Xin Li, Jing Chen, Xianmin Song, Hongmei Jing, Yuhua Li, Siguo Hao, Wenjun Wu, Yamin Tan, Jian Yu, Yanmin Zhao, Xiaoyu Lai, Elaine Tan Su Yin, Yunxiong Wei, Ping Li, Jing Huang, Tao Wang, Didier Blaise, Lei Xiao, Alex H. Chang, Arnon Nagler, Mohamad Mohty, He Huang, Yongxian Hu   +32 more
doaj   +1 more source

Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1 [PDF]

, 2007
Background: AML1/RUNX1 is the most frequently mutated gene in leukaemia and is central to the normal biology of hematopoietic stem and progenitor cells. However, the role of different AML1 isoforms within these primitive compartments is unclear.
Hong, DL, Shinobu Tsuzuki, Tsuzuki, S, Dengli Hong, Enver Tariq, Tsuzuki Shinobu, Matsuo Keitaro, Keitaro Matsuo, Tariq Enver, Hong Dengli, Seto Masao, Rajeev Gupta, Matsuo, K, Gupta Rajeev, Gupta, R, Seto, M, Hong, D, Enver, T, Masao Seto   +18 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Early Diagnostic Markers for Detection of Acute Kidney Injury in Allogeneic Hematopoietic Stem Cell Transplant Recipients

, 2020
Objectives: Acute kidney injury is a relatively frequent complication of allogenic hematopoietic stem cell transplant, resulting in increased risk of morbidity and mortality.
Aki, Sahika Zeynep, Okyay, Gulay Ulusal, Gulsan Turkoz Sucak, Gulay Ulusal Okyay, Hatice Pasaoglu, Turgay Arinsoy, Ozge T. Pasaoglu, Paşaoğlu, Özge Tuğçe, Deger, Serpil Müge, Serpil Muge Deger, Erten, Yasemin, Pasaoglu, Ozge T., Suyani, Elif, Yasemin Erter, Sahika Zeynep Aki, Paşaoğlu, Hatice, Arinsoy, Turgay, Elif Suyani, Sucak, Gulsan Turkoz   +18 more
core   +2 more sources

Epstein–Barr virus reactivation in pediatric allogeneic stem cell transplant recipients: an 11-year experience on viral load and B lymphocyte monitoring strategy

Frontiers in Immunology
BackgroundEpstein–Barr virus (EBV) reactivation represents a frequent condition after allogeneic hematopoietic stem cell transplantation (allo-HCT) and can cause the development of a severe complication: post-transplant lymphoproliferative disease (PTLD).
Giulia Ferrando, Francesca Bagnasco, Filomena Pierri, Sara Pestarino, Gianluca Dell’Orso, Stefano Giardino, Eddi Di Marco, Maria Santaniello, Elio Castagnola, Maura Faraci   +9 more
doaj   +1 more source

Successful Management of Multifactorial Colitis in a Recipient of Hematopoietic Stem Cell Transplant: A Case Report

Clinical Medicine Insights: Case Reports, 2008
Recipients of allogeneic hematopoietic stem cell transplant can develop life-threatening complications at any time following their transplants. These complications require repeated clinical assessment, appropriate and thorough screening as well as a ...
Khalid A. Al-Anazi, Asma M. Al-Jasser, Amal Abdulwahab, Entezam Sahovic, Hadeel Almana, Mohammed A. Al Fadda   +5 more
doaj   +1 more source

Supplemental Material - DNA Methylation Changes in Autologous Hematopoietic Stem Cell Transplant Patients

, 2022
Supplemental Material for DNA Methylation Changes in Autologous Hematopoietic Stem Cell Transplant Patients by Lathika Mohanraj, Hope Wolf, Scott Silvey, Jinze Liu, Amir Toor, and Theresa Swift-Scanlan in Biological Research For ...
Jinze Liu (383649), Theresa Swift-Scanlan (13963249), Amir Toor (4637119), Hope Wolf (14054668), Lathika Mohanraj (286492), Scott Silvey (14054671)   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

P1302: SALVAGE ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IS ALSO THE CURATIVE AND SAFE TREATMENT FOR RELAPSED/REFRACTORY ACUTE MYELOID LEUKEMIA IN THE ERA OF TARGETED THERAPY

HemaSphere, 2023
占祥 刘, 二辉 袁, 空 高, 启姝 秦, 琪 王, 艳智 宋, 彤 吴   +6 more
doaj   +1 more source

Dynamics of immune reconstitution in post-allogeneic hematopoietic stem cell transplant patients and effect of potential factors from Pakistani cohort

Journal of the Pakistan Medical Association
Objective: To determine the dynamics of immune reconstitution by measuring lymphocyte subsets at periodic intervals after allogenic hematopoietic stem cell transplant, and to assess the impact of potential factors influencing immune reconstitution ...
Muhammad Hussain, Muhammad Zain ul Abdeen Javed, Muhammad Omair Riaz, Mustajab Alam, Mahreen Ali Khan, Raheel Iftikhar   +5 more
doaj   +1 more source