Results 1 to 10 of about 540,083 (268)
An injectable bone marrow–like scaffold enhances T cell immunity after hematopoietic stem cell transplantation [PDF]
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for multiple disorders, but deficiency and dysregulation of T cells limit its utility.
Nisarg J. Shah+11 more
semanticscholar +4 more sources
Key Points Allogeneic hematopoietic stem cell transplantation is a curative option in patients with VEXAS syndrome and severe manifestations.
Ava Diarra+15 more
semanticscholar +1 more source
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong+7 more
doaj +1 more source
Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino+3 more
doaj +1 more source
Impact of COVID-19 and Future Emerging Viruses on Hematopoietic Cell Transplantation and Other Cellular Therapies [PDF]
COVID-19, where Co stands for corona, VI stands for virus, and D denotes disease, in the recent past referred to as 2019 novel coronavirus or 2019-nCoV, has impacted numerous lives and businesses, and has led to a surreal emergency state within world ...
Broxmeyer, Hal E., Parker, Graham C.
core +1 more source
Hematopoietic stem-cell transplantation.
Correspondence: Mark Tuthill Department of Medical Oncology, Hammersmith Hospital, imperial College National Health Service Trust, Ducane Rd, London, w12 0HS, UK Tel +44 208 383 1000 Fax +44 207 6039679 email marktuthill@doctors.org.uk Abstract: More ...
M. Ende, F. I. Ende
semanticscholar +2 more sources
Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway
Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang+10 more
doaj +1 more source
Innovations in hematopoietic stem-cell mobilization: A review of the novel CXCR4 inhibitor motixafortide [PDF]
Hematopoietic stem-cell transplantation (HCT) and stem-cell-based gene therapies rely on the ability to collect sufficient CD34+ hematopoietic stem and progenitor cells (HSPCs ...
Crees, Zachary D+2 more
core +2 more sources
Quantification of measurable residual disease (MRD) correlates with the risk of leukemia recurrence in adults with B-cell acute lymphoblastic leukemia (ALL).
Lei-Ming Cao+16 more
doaj +1 more source
Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer with a mortality rate of approximately 3–6/100,000 and is the third leading cause of cancer-related death worldwide.
Haina Wang+13 more
doaj +1 more source