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Hematopoietic stem cell transplantation
Stem Cells and Cloning: Advances and Applications, 2010 Eleftheria Hatzimichael1, Mark Tuthill21Department of Haematology, Medical School of Ioannina, University of Ioannina, Ioannina, Greece; 2Department of Medical Oncology, Hammersmith Hospital, Imperial College National Health Service Trust, London ...
Eleftheria Hatzimichael, Mark Tuthill
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BMC Medical Genomics, 2022 Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong +7 more
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Hematology, 2022 Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino +3 more
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Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway
Cancer Cell International, 2022 Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang +10 more
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Hematopoietic Stem Cell Transplantation
Clinical laboratory science : journal of the American Society for Medical Technology, 2005 Hematopoietic stem cells have been shown to provide the best chance for long term patient engraftment in bone marrow transplantation, peripheral blood stem cell transplantation, and umbilical cord blood transplantation. Characteristics of these cells include the ability to divide without differentiating; presence in bone marrow, peripheral blood, and ...
M S, Wright-Kanuth, L A, Smith
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Biomolecules & Biomedicine, 2023 Quantification of measurable residual disease (MRD) correlates with the risk of leukemia recurrence in adults with B-cell acute lymphoblastic leukemia (ALL).
Lei-Ming Cao +16 more
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Frontiers in Pharmacology, 2021 Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer with a mortality rate of approximately 3–6/100,000 and is the third leading cause of cancer-related death worldwide.
Haina Wang +13 more
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Mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]
Cytotherapy, 2009 Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of differentiating into various cell types of mesenchymal origin, such as bone, fat and cartilage.
Minoo, Battiwalla, Peiman, Hematti
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Journal of Hematology & Oncology, 2017 Background The optimal monitoring schedules and cutoff minimal residual disease (MRD) levels for the accurate prediction of relapse at all time points after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remain unclear in patients with t ...
Ya-Zhen Qin +14 more
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Experimental Hematology & Oncology, 2017 Background Ruxolitinib is a potent inhibitor of JAK1/2 with proven efficacy in myelofibrosis. In recent years, research in graft versus host disease (GVHD) has revealed the role of activation of JAK pathways in alloreactive lymphocytes. Some reports have
Mauricio Sarmiento Maldonado +7 more
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