Results 1 to 10 of about 507,539 (260)

An injectable bone marrow–like scaffold enhances T cell immunity after hematopoietic stem cell transplantation [PDF]

Nature Biotechnology, 2019
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for multiple disorders, but deficiency and dysregulation of T cells limit its utility.
Nisarg J. Shah, Angelo S. Mao, Ting-Yu Shih, Matthew D. Kerr, A. Sharda, Theresa M. Raimondo, J. Weaver, V. Vrbanac, M. Deruaz, A. Tager, D. Mooney, D. Scadden   +11 more
semanticscholar   +4 more sources

Advancing Hematopoietic Stem Cell Transplantation (HSCT) in Africa: A Pathway to Curing Hematological Disorders. [PDF]

Health Sci Rep
Ogunniyi TJ, Abdulkareem RR, Emiola AR, Bamidele TR, Wazhi GB, Arinde PO, Yisa SS, Makanjuola O, Batisani K, Ilesanmi A.   +9 more
europepmc   +3 more sources

Successful allogeneic hematopoietic stem cell transplantation in patients with VEXAS syndrome: a 2-center experience

Blood Advances, 2021
Key Points Allogeneic hematopoietic stem cell transplantation is a curative option in patients with VEXAS syndrome and severe manifestations.
Ava Diarra, Nicolas Duployez, E. Fournier, C. Preudhomme, V. Coiteux, L. Magro, B. Quesnel, M. Heiblig, P. Sujobert, F. Barraco, M. Balsat, Quentin Scanvion, E. Hachulla, D. Launay, I. Yakoub-Agha, L. Terriou   +15 more
semanticscholar   +1 more source

One novel ACOT7–NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report

BMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong, Zhijie Kang, Dan Huang, Xuehong Zhang, Yuan Gao, Haina Wang, Weiling Li, Jinsong Yan   +7 more
doaj   +1 more source

Hematopoietic stem-cell transplantation.

New England Journal of Medicine, 2006
Correspondence: Mark Tuthill Department of Medical Oncology, Hammersmith Hospital, imperial College National Health Service Trust, Ducane Rd, London, w12 0HS, UK Tel +44 208 383 1000 Fax +44 207 6039679 email marktuthill@doctors.org.uk Abstract: More ...
M. Ende, F. I. Ende
semanticscholar   +2 more sources

Real-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution

Hematology, 2022
Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino, Atsushi Jinguji, Tomoya Sato, Ayato Nakadate   +3 more
doaj   +1 more source

How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation.

Blood, 2020
CMV reactivation remains one of the most common and life-threatening infectious complications following allogeneic hematopoietic stem cell transplantation (allo-HCT) in spite of novel diagnostic technologies, several novel prophylactic agents and further
H. Einsele, P. Ljungman, M. Boeckh
semanticscholar   +1 more source

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

Cancer Cell International, 2022
Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang, Furong Wang, Fanzhi Yan, Dan Huang, Haina Wang, Beibei Gao, Yuan Gao, Zhijie Hou, Jiacheng Lou, Weiling Li, Jinsong Yan   +10 more
doaj   +1 more source

Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3-internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Haematologica, 2020
The FMS-like tyrosine kinase 3 (FLT3) gene is mutated in 25-30% of patients with acute myeloid leukemia (AML). Because of the poor prognosis associated with FLT3-internal tandem duplication mutated AML, allogeneic hematopoietic stem-cell transplantation (
A. Bazarbachi, G. Bug, F. Baron, E. Brissot, F. Ciceri, I. A. Dalle, H. Döhner, J. Esteve, Y. Fløisand, S. Giebel, M. Gilleece, N. Gorin, E. Jabbour, M. Aljurf, H. Kantarjian, M. Kharfan-Dabaja, M. Labopin, F. Lanza, F. Malard, Z. Perić, T. Prebet, F. Ravandi, A. Ruggeri, J. Sanz, C. Schmid, R. Shouval, A. Spyridonidis, J. Versluis, N. Vey, B. Savani, A. Nagler, M. Mohty   +31 more
semanticscholar   +1 more source

CSRP2 transcript levels after consolidation therapy increase prognostic prediction ability in B-cell acute lymphoblastic leukaemia

Biomolecules & Biomedicine, 2023
Quantification of measurable residual disease (MRD) correlates with the risk of leukemia recurrence in adults with B-cell acute lymphoblastic leukemia (ALL).
Lei-Ming Cao, Ya-Lan Zhou, Robert Peter Gale, Ya-Zhen Qin, Li-Xin Wu, Ming-Yue Zhao, Xiao-Su Zhao, Yu-Hong Chen, Yu Wang, Hao Jiang, Qian Jiang, Ying-Jun Chang, Yan-Rong Liu, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang, Guo-Rui Ruan   +16 more
doaj   +1 more source