Results 1 to 10 of about 540,083 (268)

An injectable bone marrow–like scaffold enhances T cell immunity after hematopoietic stem cell transplantation [PDF]

open access: yesNature Biotechnology, 2019
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for multiple disorders, but deficiency and dysregulation of T cells limit its utility.
Nisarg J. Shah   +11 more
semanticscholar   +4 more sources

Successful allogeneic hematopoietic stem cell transplantation in patients with VEXAS syndrome: a 2-center experience

open access: yesBlood Advances, 2021
Key Points Allogeneic hematopoietic stem cell transplantation is a curative option in patients with VEXAS syndrome and severe manifestations.
Ava Diarra   +15 more
semanticscholar   +1 more source

One novel ACOT7–NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report

open access: yesBMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong   +7 more
doaj   +1 more source

Real-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution

open access: yesHematology, 2022
Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino   +3 more
doaj   +1 more source

Impact of COVID-19 and Future Emerging Viruses on Hematopoietic Cell Transplantation and Other Cellular Therapies [PDF]

open access: yes, 2020
COVID-19, where Co stands for corona, VI stands for virus, and D denotes disease, in the recent past referred to as 2019 novel coronavirus or 2019-nCoV, has impacted numerous lives and businesses, and has led to a surreal emergency state within world ...
Broxmeyer, Hal E., Parker, Graham C.
core   +1 more source

Hematopoietic stem-cell transplantation.

open access: yesNew England Journal of Medicine, 2006
Correspondence: Mark Tuthill Department of Medical Oncology, Hammersmith Hospital, imperial College National Health Service Trust, Ducane Rd, London, w12 0HS, UK Tel +44 208 383 1000 Fax +44 207 6039679 email marktuthill@doctors.org.uk Abstract: More ...
M. Ende, F. I. Ende
semanticscholar   +2 more sources

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

open access: yesCancer Cell International, 2022
Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang   +10 more
doaj   +1 more source

Innovations in hematopoietic stem-cell mobilization: A review of the novel CXCR4 inhibitor motixafortide [PDF]

open access: yes, 2023
Hematopoietic stem-cell transplantation (HCT) and stem-cell-based gene therapies rely on the ability to collect sufficient CD34+ hematopoietic stem and progenitor cells (HSPCs ...
Crees, Zachary D   +2 more
core   +2 more sources

CSRP2 transcript levels after consolidation therapy increase prognostic prediction ability in B-cell acute lymphoblastic leukaemia

open access: yesBiomolecules & Biomedicine, 2023
Quantification of measurable residual disease (MRD) correlates with the risk of leukemia recurrence in adults with B-cell acute lymphoblastic leukemia (ALL).
Lei-Ming Cao   +16 more
doaj   +1 more source

Homoharringtonine Exerts Anti-tumor Effects in Hepatocellular Carcinoma Through Activation of the Hippo Pathway

open access: yesFrontiers in Pharmacology, 2021
Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer with a mortality rate of approximately 3–6/100,000 and is the third leading cause of cancer-related death worldwide.
Haina Wang   +13 more
doaj   +1 more source

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