Results 1 to 10 of about 248,982 (353)

One novel ACOT7–NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report

BMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong, Zhijie Kang, Dan Huang, Xuehong Zhang, Yuan Gao, Haina Wang, Weiling Li, Jinsong Yan   +7 more
doaj   +1 more source

Real-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution

Hematology, 2022
Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino, Atsushi Jinguji, Tomoya Sato, Ayato Nakadate   +3 more
doaj   +1 more source

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

Cancer Cell International, 2022
Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang, Furong Wang, Fanzhi Yan, Dan Huang, Haina Wang, Beibei Gao, Yuan Gao, Zhijie Hou, Jiacheng Lou, Weiling Li, Jinsong Yan   +10 more
doaj   +1 more source

CSRP2 transcript levels after consolidation therapy increase prognostic prediction ability in B-cell acute lymphoblastic leukaemia

Biomolecules & Biomedicine, 2023
Quantification of measurable residual disease (MRD) correlates with the risk of leukemia recurrence in adults with B-cell acute lymphoblastic leukemia (ALL).
Lei-Ming Cao, Ya-Lan Zhou, Robert Peter Gale, Ya-Zhen Qin, Li-Xin Wu, Ming-Yue Zhao, Xiao-Su Zhao, Yu-Hong Chen, Yu Wang, Hao Jiang, Qian Jiang, Ying-Jun Chang, Yan-Rong Liu, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang, Guo-Rui Ruan   +16 more
doaj   +1 more source

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo [PDF]

, 2017
Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (
Biondi, Andrea, Corsi, Alessandro, Donsante, Samantha, Pievani, Alice, Rambaldi, Benedetta, Remoli, Cristina, Riminucci, Mara, Robey, Pamela G., Sacchetti, Benedetto, Scagliotti, Valeria, Serafini, Marta, Vergani, Patrizia   +11 more
core   +2 more sources

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation. [PDF]

, 2020
BackgroundMucopolysaccharidosis I (MPS IH) is a lysosomal storage disease treated with hematopoietic cell transplantation (HCT) because it stabilizes cognitive deterioration, but is insufficient to alleviate all somatic manifestations.
A Ghosh, AR Pal, ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories., B Link, Bradley S. Miller, C Peters, C Peters, Chester B. Whitley, DA Stevenson, E Shapiro, E Yasuda, E. Oussoren, EA Braunlin, EA Braunlin, ED Kakkis, EJ Langereis, Elise Northrop, Elizabeth Braunlin, Ellen B. Fung, Ellen Fung, G Malm, I Visigalli, Jakub Tolar, JB Eisengart, JE Wraith, JJ Boelens, JR Hobbs, JS Weisstein, Julie B Eisengart, Julie B. Eisengart, KJ Bjoraker, Kyle Rudser, L Lopez, LA Clarke, LE Polgreen, LE Polgreen, LE Polgreen, Lynda E. Polgreen, M Aldenhoven, M Sifuentes, MA Saif, MD Poe, NE Taylor, NJ Rodgers, Paul J. Orchard, RL Washington, S Laraway, Simon A. Jones, SS Grewal, Troy C. Lund, Weston P. Miller, Y Xue   +51 more
core   +1 more source

Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells [PDF]

, 2013
Pluripotent stem cells, both embryonic stem cells and induced pluripotent stem cells, are undifferentiated cells that can self-renew and potentially differentiate into all hematopoietic lineages, such as hematopoietic stem cells (HSCs), hematopoietic ...
Inoue-Yokoo, Tomoko, Lai, Mei I., Lim, Wai Feng, Sugiyama, Daisuke, Tan, Keai Sinn   +4 more
core   +1 more source

Homoharringtonine Exerts Anti-tumor Effects in Hepatocellular Carcinoma Through Activation of the Hippo Pathway

Frontiers in Pharmacology, 2021
Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer with a mortality rate of approximately 3–6/100,000 and is the third leading cause of cancer-related death worldwide.
Haina Wang, Haina Wang, Rui Wang, Dan Huang, Sihan Li, Beibei Gao, Zhijie Kang, Bo Tang, Jiajun Xie, Fanzhi Yan, Rui Liang, Hua Li, Jinsong Yan, Jinsong Yan   +13 more
doaj   +1 more source

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]

, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
A Dar, A D’Souza, A Foudi, A Nagler, A Peled, AM Greenbaum, AW Roberts, B Nervi, CC Bleul, CL Semerad, D Obrecht, DE Harrison, F Ferraro, F Liu, GA Velders, GL Uy, H Balaguer, H Bonig, H Bonig, H Bonig, H Bonig, H Bonig, HE Broxmeyer, IG Winkler, JP Levesque, JP Levesque, K Balabanian, MA Pulsipher, MA Ryan, MJ Christopher, MM Mueller, MP Rettig, MZ Ratajczak, N Amariglio, P Anderlini, P Anderlini, P Anderlini, S Akizuki, SJ DeMarco, SJ Szilvassy, SM Devine, SP Fricker, T Lapidot, TA Lane, V Saini, WC Liles, Y Katayama, Y Takamatsu   +47 more
core   +1 more source

Non-infectious pulmonary complications of hematopoietic stem cell transplantation [PDF]

, 2014
Noninfectious pulmonary complications of hematopoietic stem cell transplant are currently more prevalent than infectious complications. Unfortunately, the pathophysiology basis is not completely understood.
Baloglu, Orkun, McArthur, Jennifer, Rowan, Courtney   +2 more
core   +1 more source