Results 11 to 20 of about 321,886 (190)

Hematoporphyrin derivative-mediated photodynamic techniques for the diagnosis and treatment of chordoma

Photodiagnosis and Photodynamic Therapy
Background: Chordoma is a rare congenital low-grade malignant tumor characterized by infiltrative growth. It often tends to compress important intracranial nerves and blood vessels, making its surgical treatment extremely difficult. Besides, the efficacy
Lei Li, Kai-lun Wei, Ming-song Liu, Qi-lin Wang, Tong-fei Zeng, Rui-zhe Chen, Xue-wei Xia, Hong-tian Zhang   +7 more
doaj   +2 more sources

Efficacy and Safety of DVDMS-Photodynamic Therapy for Dysphagia in Advanced Esophageal Cancer: A Phase II Clinical Trial. [PDF]

Cancer Sci
In this single‐arm Phase II trial, cosiporfin sodium‐mediated photodynamic therapy demonstrated efficacy in alleviating dysphagia and improving quality of life for patients with advanced esophageal cancer, with rapid onset, sustained efficacy, and good tolerability.
Zhou J, Gao S, Yuan J, Chen H, Shu Y, Fan H, Cao Y, Shan T, Dong C, Zhang H, Song Q, Xin B, Zhang H, Lu Z, Shen L.   +14 more
europepmc   +2 more sources

Uptake of hematoporphyrin derivative by atheromatous plaques: Studies in human in vitro and rabbit in vivo [PDF]

, 1986
Hematoporphyrin derivative, a photosensitive material used to identify and treat neoplastic tissue in humans, has been found to localize in atheromatous plaques in animals and has recently been found in postmortem human atherosclerotic plaques. It is not
Spokojny, Artur M., Serur, Juan R., Skillman, John, Richard Spears, J.   +3 more
core   +1 more source

Derivative observations in Gaussian Process models of dynamic systems [PDF]

, 2003
Gaussian processes provide an approach to nonparametric modelling which allows a straightforward combination of function and derivative observations in an empirical model.
Rasmussen, C.E., Murray-Smith, R., Solak, E., Leithead, W.E., Leith, D.J.   +4 more
core   +8 more sources

Pharmacokinetics of Photogem Using Fluorescence Spectroscopy in Dimethylhydrazine-Induced Murine Colorectal Carcinoma

International Journal of Photoenergy, 2012
This study aimed to investigate the pharmacokinetics of a hematoporphyrin derivative in colonic tumors induced by dimethylhydrazine and adjacent normal colon in Wistar rats using an in vivo fluorescence spectroscopy technique.
Raduan Hage, Juliana Ferreira, Vanderlei Salvador Bagnato, José Dirceu Vollet-Filho, Hélio Plapler   +4 more
doaj   +1 more source

Tumour Localization by Means of Laser-Induced Fluorescence in Hematoporphyrin Derivative (HPD) — Bearing Tissue

, 1985
Following systemic injection, hematoporphyrin derivative (HPD) is known to be selectively retained in malignant tissue. This property can be used in a two-fold way: a) for localizing tumours by observing the characteristic dual-peaked laser-induced ...
Andersson, S., Svanberg, Sune,, Kjellén, Elisabeth,, Sjöholm, E, Svanberg, Katarina,, Ankerst, Jaro,, Montan, S, Lund University.   +7 more
core   +2 more sources

Local neurotoxicity of hematoporphyrin derivative following intracerebral injection

, 1995
The present study reports on toxicity of hematoporphyrin derivative (HpD) for normal brain tissue in vivo without the addition of light. Hematoporphyrin derivative was injected by slow infusion in rat brains.
Kamphorst, W., Sterenborg, H. J., Wolbers, J. G., Noske, D. P.   +3 more
core   +1 more source

Hematoporphyrine injection‐based photodynamic therapy for Perianal Paget's disease: A case report

Photodiagnosis and Photodynamic Therapy
Paget's disease of the perianal skin (PPD) is a rare form of extramammary Paget's disease, which can manifest as either a primary intraepithelial adnexal neoplasm or as a secondary condition resulting from the spread of an underlying colorectal lesion ...
Y Zhao, XF Sun, CX Li, ZX Zhou, DX Wang, ZJ Zhao, GL Zhang, YM Chen, XL Wang   +8 more
doaj   +1 more source

Enhancement of Hematoporphyrin Derivative Uptake in Vitro and in Vivo by Tumor Cells in the Presence of Lanthanum

, 1985
Hematoporphyrin derivative is currently used as a photochemotherapeutic agent in the treatment of neoplasms. The uptake of hematoporphyrin derivative was determined in vitro and as a function of time with Ehrlich ascites cells in the presence of ...
Marie-Christine Crone-Escanye, Jacques Robert, Léopold J. Anghileri   +2 more
core   +1 more source

In Vivo Mediator Release and Degranulation of Mast Cells in Hematoporphyrin Derivative-Induced Phototoxicity in Mice [PDF]

, 1987
This study was designed to assess the role of the mast cell in the early phase of hematoporphyrin derivative (HPD)-induced phototoxicity. BALB/c mice were rendered phototoxic by i.p.
Soter, Nicholas A., Kerdel, Francisco A., Lim, Henry W   +2 more
core   +1 more source