Results 11 to 20 of about 1,889 (199)

Hematoporphyrin derivative-mediated photodynamic techniques for the diagnosis and treatment of chordoma

open access: yesPhotodiagnosis and Photodynamic Therapy
Background: Chordoma is a rare congenital low-grade malignant tumor characterized by infiltrative growth. It often tends to compress important intracranial nerves and blood vessels, making its surgical treatment extremely difficult. Besides, the efficacy
Lei Li   +7 more
doaj   +2 more sources

Pharmacokinetics of Photogem Using Fluorescence Spectroscopy in Dimethylhydrazine-Induced Murine Colorectal Carcinoma

open access: yesInternational Journal of Photoenergy, 2012
This study aimed to investigate the pharmacokinetics of a hematoporphyrin derivative in colonic tumors induced by dimethylhydrazine and adjacent normal colon in Wistar rats using an in vivo fluorescence spectroscopy technique.
Raduan Hage   +4 more
doaj   +1 more source

Tumour Localization by Means of Laser-Induced Fluorescence in Hematoporphyrin Derivative (HPD) — Bearing Tissue

open access: yes, 1985
Following systemic injection, hematoporphyrin derivative (HPD) is known to be selectively retained in malignant tissue. This property can be used in a two-fold way: a) for localizing tumours by observing the characteristic dual-peaked laser-induced ...
Andersson, S.   +7 more
core   +2 more sources

Uptake of hematoporphyrin derivative by atheromatous plaques: Studies in human in vitro and rabbit in vivo

open access: yes, 1986
Hematoporphyrin derivative, a photosensitive material used to identify and treat neoplastic tissue in humans, has been found to localize in atheromatous plaques in animals and has recently been found in postmortem human atherosclerotic plaques. It is not
Spokojny, Artur M.   +3 more
core   +1 more source

Mechanism of Tumor Destruction Following Photodynamic Therapy With Hematoporphyrin Derivative, Chlorin, and Phthalocyanine [PDF]

open access: yes, 1988
The effect of photodynamic therapy on the tumor microvasculature in the first few hours after treatment was studied at the light and electron microscopy levels.
Nelson, J Stuart   +4 more
core   +1 more source

Enhancement of Hematoporphyrin Derivative Uptake in Vitro and in Vivo by Tumor Cells in the Presence of Lanthanum

open access: yes, 1985
Hematoporphyrin derivative is currently used as a photochemotherapeutic agent in the treatment of neoplasms. The uptake of hematoporphyrin derivative was determined in vitro and as a function of time with Ehrlich ascites cells in the presence of ...
Marie-Christine Crone-Escanye   +2 more
core   +1 more source

Hematoporphyrine injection‐based photodynamic therapy for Perianal Paget's disease: A case report

open access: yesPhotodiagnosis and Photodynamic Therapy
Paget's disease of the perianal skin (PPD) is a rare form of extramammary Paget's disease, which can manifest as either a primary intraepithelial adnexal neoplasm or as a secondary condition resulting from the spread of an underlying colorectal lesion ...
Y Zhao   +8 more
doaj   +1 more source

Local neurotoxicity of hematoporphyrin derivative following intracerebral injection

open access: yes, 1995
The present study reports on toxicity of hematoporphyrin derivative (HpD) for normal brain tissue in vivo without the addition of light. Hematoporphyrin derivative was injected by slow infusion in rat brains.
Kamphorst, W.   +3 more
core   +1 more source

DNA Damage and Cell Cycle Arrest Induced by Protoporphyrin IX in Sarcoma 180 Cells

open access: yesCellular Physiology and Biochemistry, 2013
Background: Porphyrin derivatives have been widely used in photodynamic therapy as effective sensitizers. Protoporphyrin IX (PpIX), a well-known hematoporphyrin derivative component, shows great potential to enhance light induced tumor cell damage ...
Qing Li   +5 more
doaj   +1 more source

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