Results 31 to 40 of about 1,889 (199)

The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models

Photochemistry and Photobiology, EarlyView.
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva, Rebeca Barros Nascimento, Giovanna Lopes Carvalho, Rebeca Boltes Cecatto, Maria Stella Moreira, Maria Fernanda Setúbal Destro Rodrigues   +5 more
wiley   +1 more source

The Preparation of Analogs of the Ether-Linked Dimer and Oligomer Components of Hematoporphyrin Derivative

, 1991
The preparation of ether-linked porphyrin dimers and oligomers which are analogues of those present in the anticancer drugs hematoporphyrin derivative and Photofrin IIR is described. These materials are prepared from the appropriately substituted
AD Ward, CJ Byrne
core   +1 more source

Comparison of fluorescence and photodynamic activities of whole hematoporphyrin derivative and its enriched active components. [PDF]

, 1985
The in vivo biologic activities of the hematoporphyrin derivative (Photofrin) and the enriched, so-called "active fraction" (Photofrin II) were determined by measuring the necrosis produced in implanted tumors in DBA/2Ha mice exposed to various total ...
Wright, WH, Nelson, JS, Berns, MW
core   +1 more source

Hematoporphyrin derivative-photodynamic therapy (HpD-PDT) for extensive vulvar and vaginal Bowen's disease: A case report

Photodiagnosis and Photodynamic Therapy
Bowen's disease (BD) is an intraepithelial squamous cell carcinoma (SCC) that commonly affects older individuals, with the vulva being a prevalent site in women.
Xiaoqing Xiang, Yanliang Li, Can Shi, Runqun Liu, Guozhang Ma, Yunyun Cao, Lianheng Xia, Jie Gao   +7 more
doaj   +1 more source

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

AIEgens: An Exemplary Template for “One‐for‐All” Multimodal Phototheranostics

Aggregate, Volume 7, Issue 4, April 2026.
This review establishes a consensus that AIEgens serve as a quintessential template for “one‐for‐all” multimodal phototheranostics and systematically articulates the underlying rationale from a photophysical perspective. It comprehensively examines corresponding molecular engineering principles and performance optimization tactics, framed within the ...
Miaomiao Kang, Xue Li, Shuaiyin Zhang, Hao Yang, Caifa You, Yuxun Ding, Chunying Fu, Zhijun Zhang, Dong Wang, Ben Zhong Tang   +9 more
wiley   +1 more source

Picosecond time-resolved fluorescence spectroscopy of hematoporphyrin derivative [PDF]

, 1984
The picosecond time-resolved fluorescence decays I(t) and spectra I(λ, t) for hematoporphyrin derivative (HPD) in a phosphate buffer saline aqueous solution at different concentrations (8.4 x 10^[-6] ～ 8.4 x 10^[-3] M) are measured by a two-dimensional ...
Nomura, Masahide, M. Yamashita, K. Aizawa, Sato, Takuzo, Aizawa, Katsuo, S. Kobayashi, Kobayashi, Shunsuke, M. Nomura, T. Sato, Yamashita, Mikio   +9 more
core   +1 more source

The application of hyaluronic acid-derivatized carbon nanotubes in hematoporphyrin monomethyl ether-based photodynamic therapy for in vivo and in vitro cancer treatment

International Journal of Nanomedicine, 2013
Jinjin Shi,* Rourou Ma,* Lei Wang, Jing Zhang, Ruiyuan Liu, Lulu Li, Yan Liu, Lin Hou, Xiaoyuan Yu, Jun Gao, Zhenzhong Zhang School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, People's Republic of China*These authors ...
Shi J, Ma R, Wang L, Zhang J, Liu R, Li L, Liu Y, Hou L, Yu X, Gao J, Zhang Z   +10 more
doaj