Results 51 to 60 of about 1,889 (199)

Implanted Miniature Light Devices for Phototherapeutics

Advanced Therapeutics, Volume 9, Issue 1, January 2026.
Modern phototherapeutics has many attractive features; however, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts usage to superficial sites of disease. To mitigate this major problem, researchers and clinicians are actively developing miniature implanted light devices that can be implanted within a
Hailey S. Sanders, Catherine G. Price, Ana F. de Almeida Barreto, Sunghoon Rho, Thomas D. O'Sullivan, Bradley D. Smith   +5 more
wiley   +1 more source

Effectiveness of Laser Photoradiation Therapy following Hematoporphyrin Derivative Administration in the Experimental MS-2 Tumor Model

, 1983
The effectiveness of laser photoradiation therapy with hematoporphyrin derivative sensitization was tested in the MS-2 sarcoma. This solid tumor, transplanted into the pad of the hind leg of BALB/c mice, was found to be a sensitive experimental model ...
Renato Marchesini, Giannino Fava, Elsa Melloni, Lucia Locati, Franco Zunino, Giuseppina Savi, Gabriella Pezzoni   +6 more
core   +1 more source

Flash Photodynamic Therapy – How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments

Advanced Science, Volume 13, Issue 1, 5 January 2026.
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut, Fábio A. Schaberle, José Sereno, Lígia C. Gomes‐da‐Silva   +3 more
wiley   +1 more source

Hematoporphyrin derivative photochemotherapy of spontaneous animal tumors : clinical results with optimized drug dose

, 1984
Hematoporphyrin derivative (HpD) photochemotherapy was performed on 13 primary spontaneous tumors in dog and cat. The animals received an optimized drug dose of 5 mg/kg body wt i.v. 48 h before the first treatment with laser light at 631 nm.
R. Cheli, D. Fonda, A. Andreoni, R. Cubeddu, C.M. Mortellaro, F. Addis   +5 more
core   +1 more source

Tetra‐Cationic Pyridyl‐Porphyrins With Peripheral Rhenium(I) Complexes: Photophysics, Photobiological, and BSA‐Binding Properties

European Journal of Inorganic Chemistry, Volume 29, Issue 1, January 1, 2026.
Synthesis, photophysical and electrochemical characterization of tetra‐cationic porphyrins containing Re(I) complexes and BSA‐binding properties In this article, isomeric tetra‐cationic porphyrins with rhenium(I)‐carbonyl‐phenanthroline complexes at the peripheral N‐pyridyl positions 3ReP and 4ReP were evaluated for structural characterization ...
Rafaela C. Copello, André S. Polo, Rafael de Q. Garcia, Leonardo De Boni, Luiz Antônio Sodré Costa, Henrique F. V. Victória, Klaus Krambrock, Otávio A. Chaves, Bernardo A. Iglesias   +8 more
wiley   +1 more source

Treatment of head and neck cancer with photodynamic therapy: results after one year

, 1995
Photodynamic therapy (PDT) is a new and promising treatment modality for the treatment of malignant disease. This paper reports the preliminary experience of our group in the use of this therapy for the treatment of tumours arising in the head and neck ...
McKelvie, P, Kenyon, GS, Gardiner, Q, DeJode, ML, Dilkes, MG   +4 more
core  

Photodynamic therapy of spontaneous animal tumors using the active component of hematoporphyrin derivative (DHE) as photosensitizing drug : clinical results

, 1987
Photodynamic therapy was performed on 25 primary spontaneous tumors in dogs and cats. The animals were injected with 2.5 mg/kg body wt. of tumor localizing fraction of hematoporphyrin derivative and treated 48 h later with laser light at 631 nm.
R. Cheli, D. Fonda, R. Cubeddu, C.M. Mortellaro, F. Addis   +4 more
core   +1 more source

Definitive bronchoscopic photodynamic therapy for low-grade endobronchial mucoepidermoid carcinoma adjacent to the carina

Photodiagnosis and Photodynamic Therapy
Pulmonary mucoepidermoid carcinoma (PMEC) is a rare salivary gland-type primary lung malignancy arising from the tracheobronchial submucosal glands.
Zongfei Yu, Liwei Cui, Aga Jimu, Pengfei Yu   +3 more
doaj   +1 more source

Mitochondria‐Targeted AIE Materials for Oxidative Stress‐Mediated Cancer Therapy and Beyond

Aggregate, Volume 6, Issue 12, December 2025.
This review summarizes recent advances in mitochondria‐targeted AIE materials that enable controllable oxidative stress for cancer therapy and beyond. It highlights the potential of such exogenous oxidative stress in innovative therapeutic applications and biological regulation, while also outlining key limitations and future perspectives.
Na Hao, Bohong Chen, Xinxiang Wei, Yixuan Bao, Ru Zhang, Pu Chen, Jia Liu, Heqi Gao, Rongfu Tu, Chao Chen   +9 more
wiley   +1 more source

Hematoporphyrin Photoradiation Therapy for Iris Neovascularization: A Preliminary Report

, 1984
• Photoradiation therapy is a new technique currently under clinical investigation for the treatment of a variety of solid malignant tumors. The technique involves intravenous (IV) administration of hematoporphyrin derivative, a photosensitizing compound
Tse, David T, Packer, Andrew J, Hayreh, Sohan Singh, Gu, Xun-Qing   +3 more
core   +1 more source