Results 1 to 10 of about 120,136 (313)

Application of Carbon Ion and Its Sensitizing Agent in Cancer Therapy: A Systematic Review

Frontiers in Oncology, 2021
Carbon ion radiation therapy (CIRT) is the most advanced radiation therapy (RT) available and offers new opportunities to improve cancer treatment and research.
Xiaolin Wang, Xiaojun Chen, Guangfei Li, Xiao Han, Tianxin Gao, Weifeng Liu, Xiaoying Tang   +6 more
doaj   +2 more sources

Surgical adjuvant therapy in colon carcinoma: A human tumor spheroid model for evaluating radiation sensitizing agents [PDF]

Cancer, 1981
HT-29 human colon tumor cells growing as spheroids have been evaluated as a model system for measuring the response of human colon tumor cell to antineoplastic agents. HT-29 cells have been capacity to form spheroids up to 1 mm or more in diameter when grown in spinner culture.
R M, Barone, P, Calabro-Jones, T N, Thomas, T R, Sharp, J E, Byfield   +4 more
openaire   +3 more sources

Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy

Advances in Radiation Oncology, 2023
Purpose: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease.
Husain Yar Khan, PhD, Mandana Kamgar, MD, Amro Aboukameel, MS, Sahar Bannoura, MS, Brian Y. Chung, PhD, Yiwei Li, MD, Mohammed Najeeb Al Hallak, MD, Philip A. Philip, MD, PhD, Susan Tsai, MD, Sanjeev Luther, MBA, William A. Hall, MD, Asfar S. Azmi, PhD   +11 more
doaj   +2 more sources

Antagonizing CD105 enhances radiation sensitivity in prostate cancer. [PDF]

Oncogene, 2018
Radiation therapy is the primary intervention for nearly half of the patients with localized advanced prostate cancer and standard of care for recurrent disease following surgery.
Andres, Allen, Angara, Bryan, Bhowmick, Neil A, Duong, Frank, Gottlieb, Roberta, Haldar, Subhash, Liu, Zhenqiu, Madhav, Anisha, Mishra, Rajeev, Zumsteg, Zachary S   +9 more
core   +2 more sources

Recent progress of hydrogel-based local drug delivery systems for postoperative radiotherapy

Frontiers in Oncology, 2023
Surgical resection and postoperative radiotherapy remained the most common therapeutic modalities for malignant tumors. However, tumor recurrence after receiving such combination is difficult to be avoided because of high invasiveness and radiation ...
Yandong Xie, Yandong Xie, Mingxi Liu, Chang Cai, Chengkun Ye, Tangjun Guo, Kun Yang, Hong Xiao, Xianglong Tang, Xianglong Tang, Hongyi Liu   +10 more
doaj   +2 more sources

Selenium-Curcumin-PEG Nanoparticles Radiosensitization for Intensity-Modulated Radiation Therapy of Lung Tumor Cells: In Vitro Synergistic Combination Therapy [PDF]

Journal of Biomedical Physics and Engineering
Background: Lung cancer is a leading cause of cancer-related mortality worldwide, underscoring the need for the development of more effective treatment strategies. Radiotherapy (RT), particularly intensity-modulated radiation therapy (IMRT), has enhanced
Farid Mortazavi, Paria Tamaddon, Ali Ketabi, Hanieh Haghighi, Kiana Khajeheian, Masoud Haghani, Tahereh Mahmoudi, Sadegh Masjoodi, Masoud Negahdary, Naghmeh Sattarahmady   +9 more
doaj   +2 more sources

ALA-RDT in GBM: protocol of the phase I/II dose escalation trial of radiodynamic therapy with 5-Aminolevulinic acid in patients with recurrent glioblastoma

Radiation Oncology
Background Despite improvements in surgical as well as adjuvant therapies over the last decades, the prognosis for patients with glioblastoma remains poor.
Niklas Benedikt Pepper, Hans Theodor Eich, Michael Müther, Michael Oertel, Stephan Rehn, Dorothee Cäcilia Spille, Walter Stummer   +6 more
doaj   +2 more sources

Evaluating the Radiosensitization Effect of Hydroxyapatite Nanoparticles on Human Breast Adenocarcinoma Cell Line and Fibroblast [PDF]

Iranian Journal of Medical Sciences, 2020
Background: Nanohydroxyapatite (nHAP) exhibit anti-proliferative effects on various cancer cells. However, to date, there are only a few studies on the radiosensitization effect of nHAP.
Mitra Soleimani, Fatemeh Elmi, Seyyed Hossein Mousavie Anijdan, Maryam Mitra Elmi   +3 more
doaj   +1 more source

Gadolinium nanoparticles and contrast agent as radiation sensitizers [PDF]

Physics in Medicine and Biology, 2015
The goal of the present study was to evaluate and compare the radiosensitizing properties of gadolinium nanoparticles (NPs) with the gadolinium contrast agent (GdCA) Magnevist(®) in order to better understand the mechanisms by which they act as radiation sensitizers. This was determined following either low energy synchrotron irradiation or high energy
Taupin, F., Flaender, M., Delorme, R., Brochard, T., Mayol, J.F., Arnaud, J., Perriat, P., Sancey, Lucie, Lux, F., Barth, R.F., Carrière, M., Ravanat, J.L., Elleaume, H.   +12 more
openaire   +4 more sources

EPIGENETIC MECHANISMS OF SOY ISOFLAVONES IN PROSTATE CANCER TREATMENT

Sabiad, 2022
Soy intake has been associated with a lower risk of prostate cancer. Soybeans contain isoflavones, genistein, daidzein and glycitein, which have shown anti-cancer effects in cell culture and animal studies.
Ömer Küçük
doaj   +1 more source