Breast cancer as photodynamic therapy target: Enhanced therapeutic efficiency by overview of tumor complexity [PDF]
, 2014 Photodynamic therapy is a minimally invasive and clinically approved procedure for eliminating selected malignant cells with specific light activation of a photosensitizer agent.
Lamberti, María Julia +2 more
core +1 more source
Materials Today Bio, 2020 Multimodal therapy is often used in oncology to overcome dosing limitations and chemoresistance. Recently, combination immunoradiotherapy has shown great promise in a select subset of patients with colorectal cancer (CRC).
M.R. Landry +6 more
doaj +1 more source
Dinitroazetidines Are a Novel Class of Anticancer Agents and Hypoxia-Activated Radiation Sensitizers Developed from Highly Energetic Materials [PDF]
Cancer Research, 2012 Abstract In an effort to develop cancer therapies that maximize cytotoxicity, while minimizing unwanted side effects, we studied a series of novel compounds based on the highly energetic heterocyclic scaffold, dinitroazetidine. In this study, we report the preclinical validation of 1-bromoacetyl-3,3-dinitroazetidine (ABDNAZ), a ...
Shoucheng, Ning +5 more
openaire +3 more sources
First examples of pyran based colorants as sensitizing agents of p-Type Dye-Sensitized solar cells [PDF]
, 2017 Three different pyran based dyes were synthesized and tested for the first time as photosensitizers of NiO based p-type dye-sensitized solar cells (p-DSSC).
Bonomo, Matteo +4 more
core +1 more source
Cross-sensitivity to DNA-damaging agents in radiation-sensitive mutants of murine leukemia cells. [PDF]
Journal of Radiation Research, 1986 Two independently isolated radiation-sensitive mutants, M10 and LX830, of mouse L5178Y cells were compared for their sensitivity to various DNA-damaging agents. These two mutants share hypersensitivity to gamma rays, bleomycin, arabinofuranosyl cytosine (Ara-C) and aphidicolin.
K, Sato +4 more
openaire +2 more sources
Mechanisms for Tuning Engineered Nanomaterials to Enhance Radiation Therapy of Cancer
Advancement of science, 2020 Engineered nanomaterials that produce reactive oxygen species on exposure to X‐ and gamma‐rays used in radiation therapy offer promise of novel cancer treatment strategies.
Sandhya Clement +7 more
semanticscholar +1 more source
European Journal of Medical Research, 2022 Background Charged particle beams from protons to carbon ions provide many significant physical benefits in radiation therapy. However, preclinical studies of charged particle therapy for prostate cancer are extremely limited.
Tian-Qi Du +12 more
doaj +1 more source
Targeting ATM pathway for therapeutic intervention in cancer [PDF]
, 2012 The Ataxia Telangiectasia Mutated gene encodes the ATM protein, a key element in the DNA damage response (DDR) signalling pathway responsible for maintaining genomic integrity within the cell.
Chakarov, Stoyan +4 more
core +3 more sources
Efficiency Comparison between Radiotherapy Alone And In The Presence of Radio- or Photo- Sensitizers on Viability of DFW and HT29 Cell Lines: From Simulations to Experimental Results [PDF]
Iranian Journal of Medical PhysicsIntroduction: Radiotherapy (RT) is a conventional cancer treatment which address needs of most cancerous patients. However, toxicity of high X-ray energies increases side effects to the normal tissues.
Farideh Hosseini +3 more
doaj +1 more source
The suppression of DNA repair induced by PARP-1 inhibitors rucaparib and olaparib in combination with the radiopharmaceutical 131I-MIBG in noradrenaline transporter-expressing xenograft tumors [PDF]
, 2018 No abstract ...
Gaze, Mark N. +4 more
core +1 more source