Development of a Preclinical Therapeutic Model of Human Brain Metastasis with Chemoradiotherapy [PDF]
, 2013 Currently, survival of breast cancer patients with brain metastasis ranges from 2 to 16 months. In experimental brain metastasis studies, only 10% of lesions with the highest permeability exhibited cytotoxic responses to paclitaxel or doxorubicin ...
Hernández, Vanessa +4 more
core +3 more sources
Dose-Response, 2007 Routine diagnostic X-rays (e.g., chest X-rays, mammograms, computed tomography scans) and routine diagnostic nuclear medicine procedures using sparsely ionizing radiation forms (e.g., beta and gamma radiations) stimulate the removal of precancerous ...
Bobby R. Scott, Jennifer Di Palma
doaj +1 more source
Treating cutaneous T-cell lymphoma with highly irregular surfaces with photon irradiation using rice as tissue compensator. [PDF]
, 2015 PurposeCutaneous T-cell lymphoma (CTCL) is known to have an excellent response to radiotherapy, an important treatment modality for this disease.
Chakravarti, Arnab +9 more
core +2 more sources
Applications of Focused Ultrasound for the Treatment of Glioblastoma: A New Frontier
Cancers, 2022 Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median overall survival despite aggressive treatment with resection, chemotherapy, and radiation therapy.
A. Hersh +7 more
semanticscholar +1 more source
Fluoroquinolones as enhancers of photocarcinogenesis: Proposed pathomechanisms
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2022 Fluoroquinolones are photosensitizing drugs in humans, as they can enhance effects of ultraviolet A (UVA) radiation on the skin. UVA causes lesions both to deoxyribonucleic acid and other cellular organelles by Type I and Type II reactions (major and ...
Ricardo Toipa Lopes, Margarida Gonçalo
doaj
Antitumor activities of metal oxide nanoparticles [PDF]
, 2015 Nanoparticles have received much attention recently due to their use in cancer therapy. Studies have shown that different metal oxide nanoparticles induce cytotoxicity in cancer cells, but not in normal cells.
Mitjans Arnal, Montserrat +1 more
core +2 more sources
Changes in Radiation Sensitivity and Steroid Receptor Content Induced by Hormonal Agents and Ionizing Radiation in Breast Cancer Cells in Vitro [PDF]
Acta Oncologica, 1996 Possible influences of tamoxifen and estradiol on in vitro radiation sensitivity and cellular receptor content after irradiation and/or tamoxifen treatment were studied in breast cancer cell lines; estrogen receptor (ER) and progesterone receptor (PgR) positive cell lines MCF-7 and MCF-7/TAM(R)-1 and the ER and PgR negative cell line MDA-MB-231.
G H, Paulsen +3 more
openaire +2 more sources
Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer. [PDF]
, 2018 BACKGROUND:Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such ...
Chen, Yibu +12 more
core +2 more sources
NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin
Scientific Reports, 2017 NEK family kinases are serine/threonine kinases that have been functionally implicated in the regulation of the disjunction of the centrosome, the assembly of the mitotic spindle, the function of the primary cilium and the DNA damage response. NEK1 shows
Talita D. Melo-Hanchuk +13 more
doaj +1 more source
The role of copper in disulfiram-induced toxicity and radiosensitisation of cancer cells. [PDF]
, 2013 Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as an anti-cancer drug and radiosensitizer. Proposed mechanisms of action include the induction of oxidative stress and inhibition of proteasome activity ...
Babich, John W +5 more
core +1 more source