Cancer Letters, 2020 Colorectal cancer (CRC) is a leading cause of cancer-related death for both men and women, highlighting the need for new treatment strategies. Advanced disease is often treated with a combination of radiation and cytotoxic agents, such as DNA damage ...
A. Duross +4 more
semanticscholar +1 more source
Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells [PDF]
, 2010 Inhibition or downregulation of Bcl-2 represents a new therapeutic approach to by-pass chemoresistance in cancer cells. Therefore, we explored the potential of this approach in breast cancer cells.
A Letai +34 more
core +1 more source
Potentiation of the abscopal effect by modulated electro-hyperthermia in locally advanced cervical cancer patients [PDF]
, 2020 Background: A Phase III randomized controlled trial investigating the addition of modulated electro-hyperthermia (mEHT) to chemoradiotherapy for locally advanced cervical cancer patients is being conducted in South Africa (Human Research Ethics Committee
Ayeni, Olusegun +4 more
core +2 more sources
The simultaneous effect of valproic acid and gamma radiation on telomerase activity and bax and Bcl-2 protein levels in MCF-7 breast cancer cell line [PDF]
, 2015 Background: Breast cancer is one of the most prevalent types of cancer. Factors such as ionizing radiation and chemotherapeutic agents can trigger apoptosis and cancer cell death.
Asadi, J. +3 more
core +1 more source
The role of copper in disulfiram-induced toxicity and radiosensitization of cancer cells [PDF]
, 2013 <p>Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as an anti-cancer drug and radiosensitizer. Proposed mechanisms of action include the induction of oxidative stress and inhibition of proteasome ...
Ballangrud +8 more
core +1 more source
International Journal of Molecular Sciences, 2018 Hyperthermia (HT) and molecular targeting agents can be used to enhance the effect of radiotherapy (RT). The purpose of this paper is to evaluate radiation sensitization by HT and different molecular targeting agents (Poly [ADP-ribose] polymerase 1 ...
M. IJff +8 more
semanticscholar +1 more source
Comparative analysis of the secondary electron yield from carbon nanoparticles and pure water medium [PDF]
, 2015 The production of secondary electrons generated by carbon nanoparticles and pure water medium irradiated by fast protons is studied by means of model approaches and Monte Carlo simulations.
de Vera, Pablo +7 more
core +3 more sources
Effect of ultraviolet and x-ray radiation on optical properties of epoxy polymers dyed with organic phosphors [PDF]
, 2003 Highly purified industrial bisphenol and cycloaliphatic epoxy oligomers of ED-24 and UP-612 brands were used to produce optically transparent products. UV radiation of a low-pressure mercury lamp with 80% of the light energy at 254 nm was used to study ...
V CH Laurinas +8 more
core +2 more sources
Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]
, 2014 The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John +5 more
core +1 more source
Seminars in Radiation Oncology, 2019 Chemoradiation has remained the standard of care treatment for many of the most aggressive cancers. However, despite effective toxicity to cancer cells, current chemoradiation regimens are limited in efficacy due to significant normal cell toxicity. Thus,
J. Schoenfeld +7 more
semanticscholar +1 more source