Results 21 to 30 of about 522,895 (247)

Virtual Hematoxylin and Eosin Transillumination Microscopy Using Epi-Fluorescence Imaging. [PDF]

PLoS ONE, 2016
We derive a physically realistic model for the generation of virtual transillumination, white light microscopy images using epi-fluorescence measurements from thick, unsectioned tissue.
Michael G Giacomelli, Lennart Husvogt, Hilde Vardeh, Beverly E Faulkner-Jones, Joachim Hornegger, James L Connolly, James G Fujimoto   +6 more
doaj   +1 more source

Differential effects of prolonged post-fixation on immunohistochemical and histochemical staining for postmortem human brains

Frontiers in Neuroanatomy
PurposeImmunohistochemical (IHC) and histochemical (HC) staining techniques are widely used on human brains that are post-fixed in formalin and stored in brain banks worldwide for varying durations, from months to decades.
Weiya Ma, Eve-Marie Frigon, Josefina Maranzano, Josefina Maranzano, Yashar Zeighami, Yashar Zeighami, Mahsa Dadar, Mahsa Dadar   +7 more
doaj   +1 more source

Novel electron microscopic staining method using traditional dye, hematoxylin

Scientific Reports, 2022
Uranyl acetate (UA) has been routinely used as a staining solution for ultrathin sections used in biological electron microscopy. As a radioactive nuclear material, UA is subject to strict international regulations.
Hiroyuki Sasaki, Hisako Arai, Emi Kikuchi, Hideki Saito, Keiko Seki, Takeshi Matsui   +5 more
doaj   +1 more source

Tetrachromic VOF/Masson's trichrome/H and E stains: Unmasking their usability in differential stromal hard tissue staining

Indian Journal of Pathology and Microbiology, 2019
Background: Identification and differentiation of stromal hard tissue components is a challenging task. Numerous methods of demonstrating these components have been worked upon in the past.
Ankita Tandon, Akriti Singh, Devi Charan Shetty, Saurabh Juneja   +3 more
doaj   +1 more source

The Histomorphometry of The Small Intestine on Turkey (Meleagris Gallopavo) at Different Age Levels

International Journal of Tropical Veterinary and Biomedical Research, 2023
This study aims to determine the histomorphometry of the small intestine of turkeys (Meleagris gallopavo) at different age levels. This study used a completely randomized design.
Dian Masyitha, Nurul Armita, Muslim Akmal, Zainuddin Zainuddin, Erdiansyah Rahmi, M. Jalaluddin, M. Nur Salim, Mustafa Sabri, Cut Dahlia Iskandar, Baidillah Zulkifli   +9 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Predicting IHC staining classes of NF1 using features in the hematoxylin channel

Journal of Pathology Informatics, 2023
Immunohistochemistry (IHC) highlights specific cell types in tissues and traditionally involves antibody staining together with a hematoxylin counterstain.
Wei Zhang, Mei Yee Koh, Deepika Sirohi, Jian Ying, Ben J. Brintz, Beatrice S. Knudsen   +5 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Inhibition of Human Serum Albumin Aggregation by Polyphenols with Similar Structures in Macromolecular Crowding Environment

Shipin gongye ke-ji
To reveal the anti-protein aggregation ability of brazilin (Bra), hematoxylin (Hto) and hematein (Hte) under physiological crowding environment, the macromolecular crowding reagent (polyethylene glycol) was used to construct a simulated crowding ...
Mengyao JIANG, Yu YAN, Jiao GUAN, Mengfan WANG, Xin PENG   +4 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source