Results 41 to 50 of about 694,144 (304)

Optimization and enhancement of H&E stained microscopical images by applying bilinear interpolation method on lab color mode [PDF]

, 2014
Background: Hematoxylin & Eosin (H&E) is a widely employed technique in pathology and histology to distinguish nuclei and cytoplasm in tissues by staining them in different colors.
Kuru, Kaya
core   +1 more source

The Histomorphometry of The Small Intestine on Turkey (Meleagris Gallopavo) at Different Age Levels

International Journal of Tropical Veterinary and Biomedical Research, 2023
This study aims to determine the histomorphometry of the small intestine of turkeys (Meleagris gallopavo) at different age levels. This study used a completely randomized design.
Dian Masyitha, Nurul Armita, Muslim Akmal, Zainuddin Zainuddin, Erdiansyah Rahmi, M. Jalaluddin, M. Nur Salim, Mustafa Sabri, Cut Dahlia Iskandar, Baidillah Zulkifli   +9 more
doaj   +1 more source

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization [PDF]

, 2009
Initiation of mineralization during endochondral ossification is a multistep process and has been assumed to correlate with specific interactions of annexins A5 and A6 and collagens.
Anderson, Anja Niehoff, Balcerzak, Balcerzak, Belluoccio, Bent Brachvogel, Berendes, Blumbach, Brachvogel, Brachvogel, Brachvogel, Bradford, Budde, Christian Frie, Collett, Damazo, Daniele Belluoccio, DiCesare, Ernst Pöschl, Friedericke Pausch, Genge, Genge, Gerke, Girkontaite, Haut Donahue, Hawkins, Hazarika, Hikiji, Hofmann, Ivan Grskovic, John F Bateman, Julia Etich, Karsenty, Karsenty, Kim, Kirsch, Kirsch, Kirsch, Koopman, Kwan, Ling, Livak, Morgan, Murshed, Pfaffl, Rety, Romeis, Sabrina Rosenbaum, Schmitz, Srivastava, Srivastava, Stephen E Moss, Ursula Schlötzer-Schrehardt, Van Gelder, White   +54 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Predicting IHC staining classes of NF1 using features in the hematoxylin channel

Journal of Pathology Informatics, 2023
Immunohistochemistry (IHC) highlights specific cell types in tissues and traditionally involves antibody staining together with a hematoxylin counterstain.
Wei Zhang, Mei Yee Koh, Deepika Sirohi, Jian Ying, Ben J. Brintz, Beatrice S. Knudsen   +5 more
doaj   +1 more source

Synaptophysin-Ki67 double stain: a novel technique that improves interobserver agreement in the grading of well-differentiated gastrointestinal neuroendocrine tumors. [PDF]

, 2017
A common problem in the assessment of Ki67 proliferative index in well-differentiated gastrointestinal neuroendocrine tumors is distinguishing tumor from non-tumor.
Beckett, Laurel, Gandour-Edwards, Regina, Gui, Dorina, Li, Yueju, Matsukuma, Karen, Olson, Kristin A   +5 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Inhibition of Human Serum Albumin Aggregation by Polyphenols with Similar Structures in Macromolecular Crowding Environment

Shipin gongye ke-ji
To reveal the anti-protein aggregation ability of brazilin (Bra), hematoxylin (Hto) and hematein (Hte) under physiological crowding environment, the macromolecular crowding reagent (polyethylene glycol) was used to construct a simulated crowding ...
Mengyao JIANG, Yu YAN, Jiao GUAN, Mengfan WANG, Xin PENG   +4 more
doaj   +1 more source

Testicular degeneration and infertility following arbovirus infection [PDF]

, 2018
Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria, Ligios, Ciriaco, Maestrale, Caterina, Manunta, Daniela, Meloni, Giorgio, Melzi, Eleonora, Oggiano, Annalisa, Palmarini, Massimo, Pintus, Davide, Puggioni, Giantonella, Rocchigiani, Angela Maria, Savini, Giovanni   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source