Regulation of the expression of ferrochelatase in a murine model of diabetes mellitus type I
Background: Diabetes produces changes on cellular hemeprotein metabolism. The last enzyme of heme biosynthetic pathway is ferrochelatase (FECH), an enzyme that catalyzes the insertion of ferrous ion into protoporphyrin IX to produce heme. The aim of this
Leda María Oliveri+2 more
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Collagenous bone matrix-induced endochondral ossification hemopoiesis. [PDF]
Transplantation of collagenous matrix from the rat diaphyseal bone to subcutaneous sites resulted in new bone formation by an endochondral sequence. Functional bone marrow develops within the newly formed ossicle.
Anderson, WA, Reddi, AH
core
Permeability of rat choriocapillaris to hemeproteins. Restriction of tracers by a fenestrated endothelium. [PDF]
The choriocapillaris is the fenestrated capillary bed in the choroid of the eye and is the major blood supply to the retinal pigment epithelium (RPE) and photoreceptor cells. Bruch's membrane (BM) is a multilaminated basement membrane that separates the choriocapillaris from the RPE. In a previous study (Pino RM, Essner E; Cell Tissue Res 208:21, 1980)
Edward Essner, Richard M. Pino
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A framework for protein classification [PDF]
It is widely understood that protein functions can be exhaustively described in terms of no single parameter, whether this be amino acid sequence or the three-dimensional structure of the underlying protein molecule. This means that a number of
Kumar, Anand, Smith, Barry
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Editorial: Metalloproteins as sensors of gaseous small molecules—From bench to bed and beyond
Eduardo H. S. Sousa, Shiliang Tian
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Peptide-oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic [PDF]
Peptide-based structures can be designed to yield artificial proteins with specific folding patterns and functions. Template-based assembly of peptide units is one design option, but the use of two orthogonal self-assembly principles, oligonucleotide ...
Christensen, Niels Johan+9 more
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PENGARUH PEMBERIAN JUS BUAH TOMAT (Lycopersicon esculentum Mill.) TERHADAP PERUBAHAN WARNA GIGI PADA PROSES PEMUTIHAN GIGI SECARA IN VITRO [PDF]
Latar belakang : Lycopersicon esculentum Mill. merupakan tanaman yang sering digunakan sebagai bahan tambahan masakan dan dikenal sebagai tomat. Tomat mengandung beberapa bahan aktif yang diduga dapat memutihkan gigi.
Pratiwi, Septiva Asih
core
Inhibitory effect of cadmium on estrogen signaling in zebrafish brain and protection by zinc [PDF]
International audienceThe present study was conducted to assess the effects of Cd exposure on estrogen signaling in the zebrafish brain, as well as the potential protective role of Zn against Cd-induced toxicity.
Amara+67 more
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Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin [PDF]
New tools that allow dynamic visualization of molecular neural events are important for studying the basis of brain activity and disease. Sensors that permit ligand-sensitive magnetic resonance imaging (MRI) are useful reagents due to the noninvasive ...
Arnold, Frances H.+8 more
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A quantitative model for oxygen uptake and release in a family of hemeproteins
Abstract Motivation: Hemeproteins have many diverse functions that largely depend on the rate at which they uptake or release small ligands, like oxygen. These proteins have been extensively studied using either simulations or experiments, albeit only qualitatively and one or two proteins at a time.
Bustamante, Juan Pablo+5 more
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