Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells
Scientific ReportsNeuroglobin (NGB) is a hexacoordinated hemeprotein mainly expressed in neurons. Following its upregulation and mitochondrial localization, NGB plays a pro-survival role against neuronal stress.
Valeria Manganelli +12 more
doaj +1 more source
Engineered Cytochrome c-Catalyzed Lactone-Carbene B–H Insertion [PDF]
, 1878 Previous work has demonstrated that variants of a heme protein, Rhodothermus marinus cytochrome c (Rma cyt c), catalyze abiological carbene boron–hydrogen (B–H) bond insertion with high efficiency and selectivity.
Chen, Kai +6 more
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Heme-protein Modified Electrodes for Highly Selective and Sensitive Detection of H[2]O[2] from Apple Juice [PDF]
, 2015 The development of an accurate, sensitive, and selective hydrogen peroxide (H2O2) diagnostic device with a low detection limit is important in the fields of biology and medicine.
Abdelsalam, M.E. +2 more
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Engineering cytochrome P450s for enantioselective cyclopropenation of internal alkynes [PDF]
, 2020 We report a biocatalytic platform of engineered cytochrome P450 enzymes to carry out efficient cyclopropene synthesis via carbene transfer to internal alkynes. Directed evolution of a serine-ligated P450 variant, P411-C10, yielded a lineage of engineered
Arnold, Frances H., Chen, Kai
core +1 more source
Immobilization of proteins in silica gel: Biochemical and biophysical properties [PDF]
, 2015 The development of silica-based sol-gel techniques compatible with the retention of protein structure and function started more than 20 years ago, mainly for the design of biotechnological devices or biomedical applications.
Abbruzzetti, S +8 more
core +1 more source
Technological Applications of Porphyrins and Related Compounds: Spintronics and Micro-/Nanomotors [PDF]
, 2019 The vital role played by porphyrins in cells and their use in therapeutic processes are well known. More recently, the technological applications of porphyrins have attracted the attention of researchers.
Araujo-Chaves, Juliana C. +3 more
core +2 more sources
The photosynthetic cytochrome c550 from the diatom Phaeodactylum tricornutum [PDF]
, 2016 The photosynthetic cytochrome c550 from the marine diatom Phaeodactylum tricornutum has been purified and characterized. Cytochrome c550 is mostly obtained from the soluble cell extract in relatively large amounts. In addition, the protein appeared to be
Bernal Bayard, Pilar +7 more
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The Purity of Two Commercial Hemeproteins. [PDF]
Acta Chemica Scandinavica, 1985 K. G. Paul +5 more
openaire +3 more sources
PERBEDAAN PENGARUH PEMBERIAN KETOROLAK DAN DEKSKETOPROFEN SEBAGAI ANALGESIA PASCA BEDAH TERHADAP AGREGASI TROMBOSIT THE DIFFERENCE EFFECTS OF KETOROLAC AND DEXKETOPROFEN ADMINISTRATION AS POST OPERATIVE ANALGESIC ON THROMBOCYTE AGGREGATION [PDF]
, 2009 ABSTRAK Latar belakang dan tujuan : Penggunaan OAINS sebagai analgesia pasca bedah mempunyai pengaruh menghambat agregasi trombosit berdasarkan rasio COX-1 / COX- 2 yang dimiliki.
Sulistyowati, Ratri
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Regulating cellular oxygen sensing by hydroxylation [PDF]
, 2017 Oxygen homeostasis under conditions of limited O2 supply requires hypoxia-dependent gene regulation. The transcription factor complex hypoxia-inducible factor 1 (HIF-1) has been recognized as the master regulator that mediates the adaptational genetic ...
Fandrey, Joachim +2 more
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