Results 111 to 120 of about 282,075 (263)
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy +7 more
wiley +1 more source
Peripheral targets for neuropathic pain
British Journal of Pharmacology, EarlyView.Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour +3 more
wiley +1 more source
Headache MedicineIntroduction Trigeminal autonomic cephalalgias (TACs) are rare primary headache disorders characterized by severe unilateral pain and ipsilateral cranial autonomic symptoms, encompassing cluster headache, paroxysmal hemicrania, hemicrania continua, and ...
Beatriz Mascarenhas Nunes +3 more
doaj +2 more sources
Hemicrania Continua With Scintillating Scotoma: A Rare Presentation. [PDF]
Cureus, 2020 Hussein A +3 more
europepmc +1 more source
Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions
Clinical Endocrinology, EarlyView.ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley +1 more source
Depressive and Anxiety Symptoms in Vestibular Migraine and Probable Vestibular Migraine
Clinical Otolaryngology, EarlyView.ABSTRACT Introduction It has been previously reported that patients with vestibular migraine (VM) are more prone to anxiety and depressive symptoms. However, the association between the pathophysiology of VM and anxiety and depressive symptoms is still unclear.
Chisato Fujimoto +6 more
wiley +1 more source
Hemicrania continua: a case responsive to piroxicam-beta-cyclodextrin.
, 1992 The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course.
M. Trucco +5 more
core +1 more source
Developmental Medicine &Child Neurology, EarlyView.This study characterized 519 children and adolescents with vertigo using clinical, diagnostic, imaging, quality‐of‐life, and demographic data, identifying vestibular migraine as the most frequent diagnosis, followed by functional dizziness and recurrent vertigo of childhood.
Doreen Huppert +7 more
wiley +1 more source
Trigeminal autonomic cephalalgias (TACs): Paroxysmal hemicrania (PH) and hemicrania continua (HC)
In this narrated slideshow, we describe the pathophysiology, epidemiology, diagnostic criteria, subtypes, workup, and management of hemicrania continua (HC) and paroxysmal hemicrania (PH).Medina, Jose L.
Jihad Yaqoob Ali Al Kharbooshi; Tommy Lik Hang Chan; J. Alexander Fraser
core