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Genome-wide association susceptibility loci for cluster headache support a role for inflammation in the pathophysiology [PDF]
The Journal of Headache and PainBackground Recent genetic findings have broadened the perspectives of cluster headache pathophysiology. Genes identified by genome wide association studies are likely to be involved in the pathophysiological mechanisms underlying the disease.
Caroline Ran +13 more
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Adrenal gland dysfunction in males with cluster headache [PDF]
The Journal of Headache and PainBackground Cluster headache is associated with compensated hypogonadism in males, suggesting impaired testicular steroidogenesis. It is unknown if adrenal steroidogenesis is dysregulated and how this is linked to cluster headache pathophysiology.
Connar Stanley James Westgate +12 more
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Hallmarks of primary headache: part 3 – cluster headache [PDF]
The Journal of Headache and PainBackground Cluster headache (CH) is a rare primary headache disorder characterized by recurrent episodes of strictly unilateral excruciating pain accompanied by trigemino-autonomic signs, which significantly impacts the quality of life, social ...
Gianluca Coppola +47 more
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Emotional dynamics during glucocorticoid treatment in chronic cluster headache – Insights from dynamic time warp analysis [PDF]
Comprehensive PsychoneuroendocrinologyBackground: Cluster headache can affect mental health due to the severe attacks, with high rates of depression and anxiety. When prophylactic treatment fails, high dose prednisone can be used as bridging therapy, but may cause neuropsychological side ...
Paulien J. van Tilborg +5 more
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The Journal of Headache and Pain, 2023 Background Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep difficulties, though it is unknown
Caroline Ran +6 more
doaj +1 more source
Cluster Headache in a Case of Ophthalmic Cysticercosis [PDF]
Journal of Clinical and Diagnostic Research, 2019 Cluster headache is considered to be a primary headache. A lot of literature has been published for apparent cluster headache like conditions arising out of organic pathologies like tumours, dissection and infection in the craniofacial area although the ...
Animesh Das, Robin Bansal
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The Journal of Headache and Pain, 2023 Background Cluster headache is a severe and disabling primary headache disorder. Galcanezumab is a monoclonal antibody against calcitonin gene-related peptide and a preventive therapy for episodic cluster headache.
Yooha Hong +4 more
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Phase dependent hypothalamic activation following trigeminal input in cluster headache
The Journal of Headache and Pain, 2020 Background Task-free imaging approaches using PET have shown the posterior hypothalamus to be specifically activated during but not outside cluster headache attacks. Evidence from task related functional imaging approaches however is scarce.
Laura H. Schulte +2 more
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Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan
The Journal of Headache and Pain, 2022 Background Cluster headache is a highly debilitating neurological disorder with considerable inter-ethnic differences. Genome-wide association studies (GWAS) recently identified replicable genomic loci for cluster headache in Europeans, but the genetic ...
Shih-Pin Chen +14 more
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Glymphatic system dysfunction in patients with cluster headache
Brain and Behavior, 2022 Introduction The aim of this study was to investigate alterations of the glymphatic system function in patients with cluster headache. Methods We enrolled patients with cluster headache and healthy controls, and they underwent brain magnetic resonance ...
Jinseung Kim +9 more
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