Results 31 to 40 of about 2,367 (191)
Rasmussen’s encephalitis with persistent epilepsy in a young man
Clinical Case Reports, 2021 Rasmussen's encephalitis (RE) is an uncommon cause of the seizure. Important key findings of RE include intractable seizure activity in children, progressive atrophy of the involved hemisphere, and small hemisphere with the large ventricle.
Van Trung Hoang +4 more
doaj +1 more source
The Putative Role of mTOR Inhibitors in Non-tuberous Sclerosis Complex-Related Epilepsy
Frontiers in Neurology, 2021 Epilepsy affects ~5 out of every 10,000 children per year. Up to one-third of these children have medically refractory epilepsy, with limited to no options for improved seizure control.
Hannah E. Goldstein +3 more
doaj +1 more source
Genetic Basis for Classification of CNS Malformations
Pediatric Neurology Briefs, 2001 A new classification of malformations of the nervous system based on patterns of genetic expression integrated with descriptive morphogenesis is proposed by specialists in pediatric neurology, neuropathology and embryology at the University of Washington
J Gordon Millichap
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2004 A hemimegalencefalia (HME) é malformação congênita cerebral rara de etiologia desconhecida que pode se apresentar com síndrome epiléptica de início precoce e resistente à terapia com anticonvulsivantes, associada a comprometimento significativo do ...
Luiz Fernando Fonseca +10 more
doaj +1 more source
Hemimegalencephaly and Hirschsprung's disease: a unique association
, 1998 A 2-year-old boy with hemimegalencephaly and Hirschsprung's disease is reported. The unique association of these two entities is considered to he the presence of a common insult or insults that affect the innervation of the bowel and the formation ...
TÜRKDOĞAN, DİLŞAD +5 more
core +2 more sources
Case Report: Hemispherotomy in the First Days of Life to Treat Drug-Resistant Lesional Epilepsy
Frontiers in Neurology, 2021 Background: Neonatal drug-resistant epilepsy is often caused by perinatal epileptogenic insults such as stroke, ischemia, hemorrhage, and/or genetic defects. Rapid seizure control is particularly important for cognitive development.
Konstantin L. Makridis +16 more
doaj +1 more source
mTOR pathway somatic variants and the molecular pathogenesis of hemimegalencephaly
Epilepsia Open, 2020 Objectives Recently, defects in the protein kinase mTOR (mammalian target of rapamycin) and its associated pathway have been correlated with hemimegalencephaly (HME).
Camila A. B. Garcia +14 more
doaj +1 more source
Hemimegalencephaly Associated With Contralateral Hemispheral Volume Loss
, 1995 Hemimegalencephaly is a rare malformation characterized by overdevelopment of one cerebral hemisphere. The opposite hemisphere is usually normal. This paper presents a 2-day-old patient with hemimegalencephaly associated with diffuse volume loss in the ...
Sener, Rn, Sener R.N.
core +1 more source
Pediatric Neurology Briefs, 2012 Researchers at the National Institutes of Health, Bethesda, MD; Children’s National Medical Center; and George Washington University, Washington, DC present 7 patients with Muenke syndrome complicated by epilepsy.
J Gordon Millichap
doaj +1 more source
Surgery for Epilepsy due to Cortical Malformation
Pediatric Neurology Briefs, 2000 Seizure outcome after surgery for focal epilepsy due to malformation of cortical development (MCD), identified by MRI, was evaluated in 35 patients aged 3 months to 47 years (median, 14 years) operated at the Cleveland Clinic Foundation.
J Gordon Millichap
doaj +1 more source