Results 201 to 210 of about 47,935 (263)
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Annals of Internal Medicine
Hemochromatosis is an inheritable condition that mainly affects White populations of European descent. Most patients remain asymptomatic, but others develop advanced organ damage that reduces quality of life and long-term survival. Arthropathy, diabetes mellitus, cirrhosis, hypogonadotropic hypogonadism, and cardiomyopathy are key clinical ...
William C, Palmer +1 more
+5 more sources
Hemochromatosis is an inheritable condition that mainly affects White populations of European descent. Most patients remain asymptomatic, but others develop advanced organ damage that reduces quality of life and long-term survival. Arthropathy, diabetes mellitus, cirrhosis, hypogonadotropic hypogonadism, and cardiomyopathy are key clinical ...
William C, Palmer +1 more
+5 more sources
Medical Clinics of North America, 1989
This article discusses the pathophysiology and clinical manifestations of idiopathic and secondary hemochromatosis. Pedigree studies documenting the hereditary evidence for hemochromatosis are discussed. Current theories for the molecular mechanisms that result in iron overload are presented.
H K, Holland, J L, Spivak
openaire +2 more sources
This article discusses the pathophysiology and clinical manifestations of idiopathic and secondary hemochromatosis. Pedigree studies documenting the hereditary evidence for hemochromatosis are discussed. Current theories for the molecular mechanisms that result in iron overload are presented.
H K, Holland, J L, Spivak
openaire +2 more sources
Expert Review of Gastroenterology & Hepatology, 2018
Introduction: Hereditary hemochromatosis (HH) is an autosomal recessive disorder that occurs in approximately 1 in 200–250 individuals. Mutations in the HFE gene lead to excess iron absorption. Excess iron in the form of non-transferrin-bound iron (NTBI)
Shmuel Golfeyz, S. Lewis, I. Weisberg
semanticscholar +1 more source
Introduction: Hereditary hemochromatosis (HH) is an autosomal recessive disorder that occurs in approximately 1 in 200–250 individuals. Mutations in the HFE gene lead to excess iron absorption. Excess iron in the form of non-transferrin-bound iron (NTBI)
Shmuel Golfeyz, S. Lewis, I. Weisberg
semanticscholar +1 more source
Hereditary Hemochromatosis — A New Look at an Old Disease
New England Journal of Medicine, 2004Antonello Pietrangelo
exaly +2 more sources
Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment
Gastroenterology, 2010 Antonello Pietrangelo
exaly +2 more sources
Clinics in Liver Disease, 2004
Hemochromatosis is a common genetic disease with a wide range of clinical expression: from no symptoms to cirrhosis of the liver. The discovery of the gene has led to a genetic blood test useful in the diagnosis of hemochromatosis. Treatment by phlebotomy is simple and efficient and can prevent the development of cirrhosis, leading to a normal life ...
openaire +2 more sources
Hemochromatosis is a common genetic disease with a wide range of clinical expression: from no symptoms to cirrhosis of the liver. The discovery of the gene has led to a genetic blood test useful in the diagnosis of hemochromatosis. Treatment by phlebotomy is simple and efficient and can prevent the development of cirrhosis, leading to a normal life ...
openaire +2 more sources
Seminars in Hematology, 2002
Juvenile hemochromatosis or type 2 hemochromatosis is a rare inherited recessive disease, which leads to severe iron overload earlier in life than HFE-related hemochromatosis. Increased transferrin saturation and serum ferritin as well as parenchymal iron deposition and liver fibrosis may be observed in childhood.
C. Camaschella +2 more
openaire +3 more sources
Juvenile hemochromatosis or type 2 hemochromatosis is a rare inherited recessive disease, which leads to severe iron overload earlier in life than HFE-related hemochromatosis. Increased transferrin saturation and serum ferritin as well as parenchymal iron deposition and liver fibrosis may be observed in childhood.
C. Camaschella +2 more
openaire +3 more sources
Current Treatment Options in Gastroenterology, 1999
The mainstay of treatment for hemochromatosis is therapeutic phlebotomy. The procedure is safe, effective, and relatively cheap. Deferoxamine (iron chelation) is necessary only in iron-loaded individuals who cannot undergo therapeutic phlebotomy. If therapy is initiated before complications develop, it is expected that no complications will ever ...
openaire +2 more sources
The mainstay of treatment for hemochromatosis is therapeutic phlebotomy. The procedure is safe, effective, and relatively cheap. Deferoxamine (iron chelation) is necessary only in iron-loaded individuals who cannot undergo therapeutic phlebotomy. If therapy is initiated before complications develop, it is expected that no complications will ever ...
openaire +2 more sources