Results 41 to 50 of about 23,592 (205)

Diverse immune functions of hemocyanins

Developmental & Comparative Immunology, 2014
Substantial evidence gathered recently has revealed the multiple functionalities of hemocyanin. Contrary to previous claims that this ancient protein is involved solely in oxygen transport within the hemolymph of invertebrates, hemocyanin and hemocyanin-derived peptides have been linked to key aspects of innate immunity, in particular, antiviral and ...
Coates, Christopher, Nairn, Jacqueline
openaire   +4 more sources

Immunological properties of oxygen-transport proteins: hemoglobin, hemocyanin and hemerythrin

Cellular and Molecular Life Sciences, 2016
It is now well documented that peptides with enhanced or alternative functionality (termed cryptides) can be liberated from larger, and sometimes inactive, proteins. A primary example of this phenomenon is the oxygen-transport protein hemoglobin.
C. Coates, H. Decker
semanticscholar   +1 more source

A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies

Analysis &Sensing, EarlyView.
An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro, Camila dos Anjos Proença, Ana Carolina da Rosa Nogarolli, Ana Fabiele Domakoski Trevisan, Thiago Neves Machado, João Carlos Degraf Muzzi, Larissa Magalhães Alvarenga, Juliana de Moura   +7 more
wiley   +1 more source

Hemocyanins from Helix and Rapana Snails Exhibit in Vitro Antitumor Effects in Human Colorectal Adenocarcinoma

Biomedicines, 2020
Hemocyanins are oxygen-transporting glycoproteins in the hemolymph of arthropods and mollusks that attract scientific interest with their diverse biological activities and potential applications in pharmacy and medicine.
Ani Georgieva, Katerina Todorova, Ivan Iliev, Valeriya Dilcheva, Ivelin Vladov, Svetlozara Petkova, Reneta Toshkova, Lyudmila Velkova, Aleksandar Dolashki, Pavlina Dolashka   +9 more
doaj   +1 more source

An automated microfluidic biosensor with bispecific rabbit monoclonal antibody and nanozyme‐bioenzyme composite for dual antibiotic detection

BMEMat, EarlyView.
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang, Yang Liu, Juntao Wang, Haichao Zhang, Wenlong Yu, Yaxin Sang, Yun Liu, Guangze Yang, Fang Gao, Shuo Wang, Shilun Feng, Xianghong Wang   +11 more
wiley   +1 more source

Extreme thermostability of tarantula hemocyanin [PDF]

FEBS Letters, 1995
Biotops with extreme temperatures such as deserts force animals to avoid or escape high temperatures by biochemical, behavioural or morphological adaptation. In this context we tested the resistance to heat of the oxygen carrier hemocyanin from the ancient tarantula Eurypelma californicum, which is found in arid zones of North America.
Sterner, Reinhard, Vogl, Thomas, Hinz, Hans-Jürgen, Penz, Franz, Hoff, Rainer, Föll, Roman, Decker, Heinz   +6 more
openaire   +2 more sources

Discovery of Novel Hemocyanin-Like Genes in Metazoans

The Biological Bulletin, 2018
Among animals, two major groups of oxygen-binding proteins are found: proteins that use iron to bind oxygen (hemoglobins and hemerythrins) and two non-homologous hemocyanins that use copper.
E. Costa-Paiva, C. G. Schrago, C. Coates, K. Halanych   +3 more
semanticscholar   +1 more source

Evolutionary patterns and structural divergence of CENH3 in legumes: Implications for haploid induction breeding

Grassland Research, EarlyView.
From structure to application: evolutionary insights and genome editing strategies for CENH3‐mediated haploid induction in legumes. Abstract Background The centromeric histone variant CENH3 is crucial for chromosome segregation and haploid induction in plants, yet its evolutionary patterns in legumes remain poorly characterized. Methods We investigated
Jialiang Zhou, Kai Wang
wiley   +1 more source

On the Ultrastructure and Function of Rhogocytes from the Pond Snail Lymnaea stagnalis. [PDF]

PLoS ONE, 2015
Rhogocytes, also termed "pore cells", occur as solitary or clustered cells in the connective tissue of gastropod molluscs. Rhogocytes possess an enveloping lamina of extracellular matrix and enigmatic extracellular lacunae bridged by cytoplasmic bars ...
Maria Kokkinopoulou, Lisa Spiecker, Claudia Messerschmidt, Mike Barbeck, Shahram Ghanaati, Katharina Landfester, Jürgen Markl   +6 more
doaj   +1 more source

Tarantula Hemocyanin Shows Phenoloxidase Activity [PDF]

Journal of Biological Chemistry, 1998
An enzyme generally catalyzes one well defined reaction with high specificity and efficiency. We report here in contrast that the copper protein hemocyanin of the tarantula Eurypelma californicum exhibits two different functions. These occur at the same active site.
H, Decker, T, Rimke
openaire   +2 more sources