Results 61 to 70 of about 12,052 (229)

MRD‐negative conversion with daratumumab monotherapy in newly diagnosed multiple myeloma patients in ≥VGPR/MRD‐positive after first‐line therapy: Final analysis of the open‐label, single‐arm multicentric phase 2 trial DART4MM

open access: yesBritish Journal of Haematology, EarlyView.
In newly diagnosed multiple myeloma patients in ≥Very Good Partial Remission (VGPR) after a first‐line therapy daratumumab as consolidation/maintenance improved long‐term minimal residual disease negativity. Summary Daratumumab is approved for front‐line and relapsed myeloma therapy.
Alessandro Gozzetti   +24 more
wiley   +1 more source

Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim   +3 more
wiley   +1 more source

Acute management of poor condition subarachnoid hemorrhage patients

open access: yes, 2012
Poor condition subarachnoid hemorrhage (SAH) patients present a high mortality and morbidity. In this study, we reviewed the acute interventional (surgical and endovascular) management of 109 SAH-poor condition patients, who were treated as early as ...
Archavlis, Eleftherios   +1 more
core   +1 more source

Perioperative Management for Patients With Spinal Muscular Atrophy Undergoing Scoliosis Surgery: A Single‐Center Retrospective Study

open access: yesOrthopaedic Surgery, EarlyView.
This largest Asian case series confirms that posterior spinal fusion for SMA scoliosis is safe and effective despite severe deformity and markedly impaired pulmonary function. Meticulous multidisciplinary care, including advanced airway planning, hemodynamic support, blood management, and proactive electrolyte correction, is critical to optimizing ...
Ai Hu   +7 more
wiley   +1 more source

The Italian hemodilution trial in acute stroke.

open access: yes, 1987
The Italian Acute Stroke Study is a prospective, multicenter, randomized, clinical trial to evaluate hemodilution in acute stroke. Thirty-one centers will recruit 1,200 patients with a recent (less than 12 hours) hemispheric acute stroke.
FABRIZI, Gian Maria
core   +1 more source

Maternal Haemoglobin and Haematocrit During Pregnancy and Stillbirth Risk: A Prospective, Population‐Based Birth Cohort Study

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Maternal anaemia is a public health issue globally, associated with adverse maternal and neonatal outcomes. However, less is known about the effects of high haemoglobin (Hb) and haematocrit (Hct) on the risk of stillbirth. Objectives We assessed the dose–response effects of dynamic changes in maternal Hb and Hct across all ...
Shuangying Li   +17 more
wiley   +1 more source

Evaluating the effects of a hospital utilisation improvement program on platelet transfusions: A pre‐post study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Annually millions of platelet concentrate (PC) are transfused worldwide. The decision regarding PC transfusion is often complex; therefore, the implementation of a hospital programme designed to streamline and facilitate the decision‐making process is beneficial. Such a programme helps standardise transfusion practices, ensures that
Piotr F. Czempik   +2 more
wiley   +1 more source

CHOICE OF THE TECHNIQUE FOR BLOOD LOSS REDUCTION IN THE RECONSTRUCTIVE ORAL SURGERY

open access: yesВестник анестезиологии и реаниматологии, 2018
Goal of the study: to define the most optimal technique for blood loss reduction during reconstructive surgeries in maxillofacilal area. Materials and methods.
A. Yu. Zaitsev   +2 more
doaj   +1 more source

Hemodilution tolerance in elderly patients without known cardiac disease

open access: yes, 1996
Hemodilution tolerance is not well defined in elderly patients. In 20 patients older than 65 yr and free from known cardiovascular disease, hemodynamic variables, ST segment deviation, and O2 consumption were determined prior to and after 6 and after 12 ...
Spahn, D R   +6 more
core   +1 more source

Is crystalloid cardioplegia a strong predictor of intra-operative hemodilution? [PDF]

open access: yes, 2014
Introduction: Complications due to hemodilution (hematocrit value less than 22%) after cardiopulmonary bypass inevitably resulted with significantly greater intensive care requirements, long hospital stays, more operative costs, and increased mortality ...
Gunday, Murat   +3 more
core   +1 more source

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