Results 81 to 90 of about 12,052 (229)

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr, Andrew J. M. Douglas, Elliott J. Jenkins, Lauren E. Maier, Jodie L. Koep, Travis D. Gibbons, Adam Field, James D. Anholm, Katharine Foster, Zoe H. Adams, Lydia L. Simpson, Jonathan P. Moore, Tinna Traustadottir, Christoph Siebenmann, Joshua C. Tremblay, Mike Stembridge   +15 more
wiley   +1 more source

Hemodilution affects the pressor response to norepinephrine.

, 1991
A hindlimb preparation of 19 male rats was used to determine the responses to norepinephrine (NE) at different levels of hemodilution at a constant flow, at increased flow and maintained pressure, and after reversal of hemodilution.
Azmy SS, Sheng Z, PEDRINELLI, ROBERTO, Estafanous FG, Tarazi R.C.   +4 more
core  

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 193-202, July 2026.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang, Kyoung Lok Min, Seungwon Yang, Jongsung Hahn, Dasohm Kim, Byung Hak Jin, Soon Uk Chae, Soo Kyung Bae, Jin Wi, Min Jung Chang   +9 more
wiley   +1 more source

The Effect of Normovolemic and Hypervolemic Hemodilution on a Microsurgical Model. Experimental Study in Rats

, 2015
BACKGROUND: Nowadays, postoperative flap perfusion impairment still occurs in free flap surgery; despite several studies on microcirculatory physiology, the effect of hemodilution is still extremely controversial. The aim of this study was to investigate
Ünal, Kerim, Özkan, Ömer, LONGO, Benedetto, Başsorgun, Cumhur İbrahim, Ögan, Önur, SANTANELLI DI POMPEO, Fabio, Özkan, Özlenen, Amoroso, Matteo   +7 more
core   +2 more sources

Effects of plasma viscosity modulation on cardiac function during moderate hemodilution

Asian Journal of Transfusion Science, 2010
Background : Previous studies have found that increasing plasma viscosity as whole blood viscosity decrease has beneficial effects in microvascular hemodynamics.
Chatpun Surapong, Cabrales Pedro
doaj  

ICU Clinicians' View on Platelet Transfusion Thresholds for a Future Trial—Protocol for an International Survey

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Thrombocytopenia is frequent in adult intensive care unit (ICU) patients and may contribute to adverse outcomes, including bleeding, morbidity and mortality. To reduce the risk of bleeding, platelet transfusions are commonly used, yet transfusion thresholds vary, and the evidence base is very limited.
Jehad Ahmad Barakji, Carl Thomas Anthon, Anders Granholm, Morten Hylander Møller, Jakob Stensballe, Anders Perner   +5 more
wiley   +1 more source

Microcirculation dysfunction and cardioprotection in cardiac surgery with cardiopulmonary bypass: mechanisms, monitoring, and therapeutic strategies

Frontiers in Cardiovascular Medicine
Cardiopulmonary bypass (CPB) is a crucial component of cardiac surgery, yet postoperative organ dysfunction remains common despite apparently adequate systemic hemodynamics.
Clark Zheng, Clark Zheng, Kelsey Muir, Kelsey Muir, Himanshu Kaushik, Keertana Yalamanchili, Keyana Zahiri, Adam Yeo, Justin Kim, Frank W. Sellke, Frank W. Sellke   +10 more
doaj   +1 more source

MPACT OF PERI-OPERATIVE NORMOVOLEMIC HEMODILUTION ON HEMOSTASIS, BLOOD LOSS AND INDICATIONS TO TRANSFUSION OF DONOR ERYTHROCYTES DURING CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS

Вестник анестезиологии и реаниматологии, 2018
Intra-operative acute normovolemic hemodilution or autologous blood transfusion, is one of the factors of the patient's blood conservation and reduction of the donor blood use.The objective: to assess the value of acute normovolemic hemodilution for the ...
N. A. Trekova, D. A. Guskov, B. A. Akselrod, O. V. Dymova, A. V. Gubko, V. G. Gladysheva   +5 more
doaj   +1 more source

Barrier Solutions to Acute Normovolemic Hemodilution

, 2018
Patient blood management is "the scientific use of safe and effective medical and surgical techniques designed to conserve blood, prevent anemia, decrease bleeding, and optimize coagulation in an effort to improve patient outcomes.
A. Pommerenke; C. Morrissey; Luca Boi
core  

Acute normovolemic hemodilution in spinal fusion surgery

, 2011
BackgroundSpinal fusion surgeries are accompanied by significant blood loss. Acute normovolemic hemodilution is one of the autologous blood transfusion techniques that is proved to improve tissue perfusion through decreasing blood viscosity. However, its
Salwa H. Waly, Nasr, Yasser M., Waly, Salwa H., Maha I. El-Dessouky, El-Dessouky, Maha I., Yasser M. Nasr   +5 more
core   +1 more source