Results 81 to 90 of about 304,292 (268)

A Smart Fluid‐Hydraulic System Based on MRF Valve Control and Its Application in Flexible Grasping

Advanced Science, EarlyView.
This study introduces a smart fluid hydraulic system using MRF valve control for flexible gripping. An MRF‐MSV with an integrated excitation coil and micro‐textured damping channels is designed and validated; micro‐texturing increases hydraulic resistance. Coupled with a soft actuator, the MRF‐MSV enables dynamic bending and grasping.
Linfeng Huo, Hui Ji, Ruidong Hong, Songlin Nie, Fanglong Yin, Zhonghai Ma   +5 more
wiley   +1 more source

Investigate the hemodynamic alterations and anxiety state levels during the surgical disimpaction of mandibular third molar

Journal of Education and Health Promotion
BACKGROUND: This study investigates the haemodynamic responses during the disimpaction process to enhance clinical awareness and perioperative care. MATERIALS AND METHODS: A prospective cohort study was conducted with 140 participants aged 18 years and ...
Addu Aravind Kumar, Siddharth Paladugu, Muthahera Mazhar, Godvine Sarepally, Anusha Borra, Himaja Kasarla, Mohammed Abidullah   +6 more
doaj   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

The effect of quadratus lumborum versus epidural block on perioperative hemodynamic status in elderly patients with cancer colon surgery

Alexandria Journal of Medicine
Background Cancer colon is a significant global cancer cause. TEA is the preferred method for treating pain after major abdominal surgery. However, it has many drawbacks.
Lina Gamal Mahmoud Rizk, Emad Eldin Abd El Monem Arida, Magdy Abdelaziz Mansour, Shahira Ahmed Mohamed Elmetainy, Engi Yousry Hashem   +4 more
doaj   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Dexmedetomidine and atipamezole on renal blood perfusion in dogs assessed by doppler flowmetry and urinalysis

Ciência Rural
: This study compared the intramuscular administration of 2.5 or 5 µg/kg of dexmedetomidine and subsequent reversal with atipamezole in domestic dogs, assessing the impact on renal function using Doppler ultrasound, urinalysis, and evaluation of ...
Luna Silvestri Souto, Gabriela Borges Conterno, Leonardo Bergmann Griebeler, Laura de Bovi Pereira, Leonardo Deschamps Fernandes, Hugo Salvador Oliveira, Mere Erika Saito, Felipe Comassetto, Nilson Oleskovicz   +8 more
doaj   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

Anthracycline-induced cardiorenal toxicity: from molecular mechanisms to clinical management

Frontiers in Cardiovascular Medicine
In oncology clinics, anthracyclines remain a cornerstone of cancer therapy. However, their clinical benefits are accompanied by substantial toxicities.
Linke Jiao, Chao Yuan, Li Wang, Yating Zhao, Guoxia Zhang, Xinyu Yang, Yonghong Gao, Fan Yang, Xinye Li, Na An, Hongcai Shang, Hongcai Shang, Yanwei Xing   +12 more
doaj   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source