Results 81 to 90 of about 422,358 (263)

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Unreliability of Pulse Contour-Derived Cardiac Output in Piglets Simulating Acute Hemorrhagic Shock and Rapid Volume Expansion

, 2011
Pulse contour-derived cardiac output for continuous hemodynamic monitoring is becoming popular in critical care. However, the data regarding its reliability during acute hemodynamic instability are inconsistent.
李枝新;王振源;黃國良;邱泓文;張宏, LEE, CHIH-HSIN;WANG, JANN-YUAN;HUANG, KUO-LIANG;CHIU, HUNG-WEN;CHANG, HUNG   +1 more
core   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

Advanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang, Xinyu Ren, Dalin Ma, Hao Pang, Wei Chen, Kaize Cai, Mei Yuan, Bingzhi Zhang, Zufang Lin, Xiaoshuai Liu   +9 more
wiley   +1 more source

Deep‐Learning‐Driven High‐Fidelity In Vivo Hyperspectral Fluorescence Imaging Under Extreme Photon‐Limited Conditions

Advanced Science, EarlyView.
Highly overlapping fluorescent signals become distinguishable in photon‐limited living organisms via advanced imaging with intelligent reconstruction. The resulting in vivo hyperspectral imaging capability reveals nanoplastic uptake and circulation in live zebrafish, providing a new approach for studying complex biological and environmental processes ...
Renjian Li, Shutao Wu, Kaixiang Li, Zhenyu An, Yuwen Ben, Guiye LI, Sunil Kumar, James Mcginty, Tawfique Hasan, Songnian Fu, Meng Zhang, LingLing Chen   +11 more
wiley   +1 more source

Immediate management of a stable patient with unstable pelvis

EFORT Open Reviews
The diagnosis of a traumatic unstable pelvis in a stable patient is a temporary concept depending on when we see the patient, as all patients presenting with hemorrhagic shock have hemodynamic stability until they become unstable.
Juan Ramón Cano, José Manuel Bogallo, Alicia Ramirez, Enrique Guerado   +3 more
doaj   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Attitudes of Anaesthesiology Specialists and Residents Toward Hemodynamic Monitoring: A National Survey Study

Objective: This descriptive survey study aims to evaluate the knowledge, attitudes, and practices of anaesthesiology specialists and residents in Türkiye regarding advanced hemodynamic monitoring in high-risk surgical patients.
Demir, Z. Aslı, BİNGÜL, EMRE SERTAÇ, AYKUT, ASLIHAN, TALİH, GAMZE, Ak\ue7a, Ba\u15fak, ERDEM, ALİ FUAT, Bing\ufcl, Emre Serta\ue7, Z. Aslı Demir, AKÇA, BAŞAK, Aykut, Asl\u131han, KARADENİZ, ÜMİT, Burhan Dost, Aykut, Aslıhan, AYDIN, MUHAMMED ENES, DOST, BURHAN, Ali Fuat Erdem, Emre Sertaç Bingül, Gamze Talih, Karadeniz, cmit, Aslıhan Aykut, Demir, Z. Asl\u131, DEMİR, ZELİHA ASLI, Başak Akça, Muhammed Enes Aydın, Ayd\u131n, Muhammed Enes, Ümit Karadeniz   +25 more
core   +1 more source

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

Unlocking Insights: A Survey on Perioperative Hemodynamic Monitoring in Kidney Transplantation Across India

Indian Journal of Transplantation
Objective: Across the globe, kidney transplant is the most frequently performed transplant surgery. Suboptimal hemodynamic monitoring in the perioperative period results in poor graft and patient outcomes.
Vipin Kumar Goyal, Saurabh Mittal, Praveenkumar Shekhrajka   +2 more
doaj   +1 more source