Results 71 to 80 of about 422,358 (263)

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms. [PDF]

Animal Model Exp Med
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Hou L, Liu X, Hu W, Liu X, Zhu W.
europepmc   +2 more sources

Hemodynamic changes in patients with diabetes

Diabetes is a chronic metabolic disorder characterized by high blood glucose levels, which can lead to dysfunction and failure of multiple organs. The prevalence of diabetes has grown significantly, with cases rising from 108 million in 1980 to 422 ...
Konrad Siebert, Milena Dybowska
core   +1 more source

Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG

Advanced Science, EarlyView.
Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan, Maria Fratello, Francesca Bonini, Samuel Medina Villalon, Zhengchen Cai, Jean‐Marc Lina, Jean‐Michel Badier, Fabrice Bartolomei, Jean Gotman, Christian G. Bénar, Christophe Grova   +10 more
wiley   +1 more source

Foundations and Advancements in Hemodynamic Monitoring: Part I-Elements of Hemodynamics [PDF]

Standard monitoring guidelines by the American Society of Anesthesiologists and European Society of Anaesthesiology and Intensive Care have not been updated for over a decade, despite rapid advancements in monitoring technology and the growing complexity
Bingül, Emre sertaç, AYKUT, ASLIHAN, Emre Sertaç Bingül, KARADENİZ, Ümit, Akca, Basak, Dost, Burhan, Gamze Talih, Zeliha Aslı Demir, AYDIN, Muhammed Enes, Aslıhan Aykut, demir, aslı z, Başak Akça, Muhammed Enes Aydın, Burhan Dost, TALIH, GAMZE, Ümit Karadeniz   +15 more
core   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Personalized hemodynamic management

, 2017
Purpose of review: To describe personalized hemodynamic management of critically ill patients in the operating room and the ICU. Recent findings: Several recent clinical studies have investigated different strategies for optimizing blood pressure (BP ...
Saugel, Bernd, Bernd Saugel, Jean-Louis Vincent, Vincent, Jean Louis, Wagner, Julia J.Y., Julia Y. Wagner   +5 more
core   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Observation of intracranial artery and venous sinus hemodynamics using compressed sensing-accelerated 4D flow MRI: performance at different acceleration factors

Frontiers in Neuroscience
ObjectiveTo investigate the feasibility and performance of 4D flow MRI accelerated by compressed sensing (CS) for the hemodynamic quantification of intracranial artery and venous sinus.Materials and methodsForty healthy volunteers were prospectively ...
Jiajun Cao, Chang Yuan, Yukun Zhang, Yue Quan, Peipei Chang, Jing Yang, Qingwei Song, Yanwei Miao   +7 more
doaj   +1 more source

Hemodynamic Monitorization of the Burn Patient

, 2011
Hemodynamic monitorization is the basic component of the medical care of the burn patients. It provides valuable information of the cardiopulmonary performance which is essential in the rapid diagnosis and treatment in the case of hemodynamic ...
Burak Eşkin, Ahmet Coşar
core