Results 111 to 120 of about 268,961 (366)

In-silico Analysis of Hemodynamic Indicators in Idealized Stented Coronary Arteries for Varying Stent Indentation [PDF]

open access: yes
In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The proposed model is applied to an idealized artery with Xience V stent for four indentation percentages and three mesh ...
arxiv   +1 more source

A lite parametric model for the Hemodynamic Response Function [PDF]

open access: yesarXiv, 2020
When working with task-related fMRI data, one of the most crucial parts of the data analysis consists of determining a proper estimate of the BOLD response. The following document presents a lite model for the Hemodynamic Response Function HRF. Between other advances, the proposed model present less number of parameters compared to other similar HRF ...
arxiv  

A Novel 3D‐Printed Microfluidic Bioreactor With Electrospun Scaffold Integration as a Platform for Cardiovascular Tissue Engineering

open access: yesJournal of Applied Polymer Science, EarlyView.
ABSTRACT Cardiovascular diseases are one of the leading causes of global mortality. Treatment methods such as bypass graft operations, while often successful, can fail in cases of systemic disease or compliance mismatch. Tissue engineered vascular grafts may offer a potential solution, by means of an implantable cell‐seeded scaffold that can integrate ...
Andrew P. Johnston   +2 more
wiley   +1 more source

Paclitaxel coated-stent for early-onset thrombosis after liver transplantation

open access: yesAnnals of Hepatology, 2007
Hepatic artery thrombosis (HAT) is the most common vascular complication of orthotopic liver transplantation (OLT) and constitutes a potential emergency during the postoperative period.
Jesús Reyes-Corona   +5 more
doaj  

Evidence for mechanisms underlying the functional benefits of a myocardial matrix hydrogel for post-MI treatment [PDF]

open access: yes, 2016
Background There is increasing need for better therapies to prevent the development of heart failure after myocardial infarction (MI). An injectable hydrogel derived from decellularized porcine ventricular myocardium has been shown to halt the post ...
Braden, Rebecca L.   +8 more
core   +1 more source

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia   +4 more
wiley   +1 more source

The role and mechanism of vascular wall cell ion channels in vascular fibrosis remodeling

open access: yesChannels
Fibrosis is usually the final pathological state of many chronic inflammatory diseases and may lead to organ malfunction. Excessive deposition of extracellular matrix (ECM) molecules is a characteristic of most fibrotic tissues.
Xiaolin Zhang   +5 more
doaj   +1 more source

Hemodynamics of Stent Implantation Procedures in Coronary Bifurcations: an in vitro study [PDF]

open access: yesarXiv, 2016
Stent implantation in coronary bifurcations presents unique challenges and currently there is no universally accepted stent deployment approach. Despite clinical and computational studies, to date, the effect of each stent implantation method on the coronary artery hemodynamics is not well understood.
arxiv  

The tacrolimus concentration‐to‐dose ratio is associated with kidney function in heart transplant recipients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen   +9 more
wiley   +1 more source

Clinical and Hemodynamic Studies of Tricuspid Stenosis [PDF]

open access: bronze, 1956
Paul N. Yu   +4 more
openalex   +1 more source

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