Results 111 to 120 of about 268,961 (366)
In-silico Analysis of Hemodynamic Indicators in Idealized Stented Coronary Arteries for Varying Stent Indentation [PDF]
In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The proposed model is applied to an idealized artery with Xience V stent for four indentation percentages and three mesh ...
arxiv +1 more source
A lite parametric model for the Hemodynamic Response Function [PDF]
When working with task-related fMRI data, one of the most crucial parts of the data analysis consists of determining a proper estimate of the BOLD response. The following document presents a lite model for the Hemodynamic Response Function HRF. Between other advances, the proposed model present less number of parameters compared to other similar HRF ...
arxiv
ABSTRACT Cardiovascular diseases are one of the leading causes of global mortality. Treatment methods such as bypass graft operations, while often successful, can fail in cases of systemic disease or compliance mismatch. Tissue engineered vascular grafts may offer a potential solution, by means of an implantable cell‐seeded scaffold that can integrate ...
Andrew P. Johnston+2 more
wiley +1 more source
Paclitaxel coated-stent for early-onset thrombosis after liver transplantation
Hepatic artery thrombosis (HAT) is the most common vascular complication of orthotopic liver transplantation (OLT) and constitutes a potential emergency during the postoperative period.
Jesús Reyes-Corona+5 more
doaj
Evidence for mechanisms underlying the functional benefits of a myocardial matrix hydrogel for post-MI treatment [PDF]
Background There is increasing need for better therapies to prevent the development of heart failure after myocardial infarction (MI). An injectable hydrogel derived from decellularized porcine ventricular myocardium has been shown to halt the post ...
Braden, Rebecca L.+8 more
core +1 more source
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia+4 more
wiley +1 more source
The role and mechanism of vascular wall cell ion channels in vascular fibrosis remodeling
Fibrosis is usually the final pathological state of many chronic inflammatory diseases and may lead to organ malfunction. Excessive deposition of extracellular matrix (ECM) molecules is a characteristic of most fibrotic tissues.
Xiaolin Zhang+5 more
doaj +1 more source
Hemodynamics of Stent Implantation Procedures in Coronary Bifurcations: an in vitro study [PDF]
Stent implantation in coronary bifurcations presents unique challenges and currently there is no universally accepted stent deployment approach. Despite clinical and computational studies, to date, the effect of each stent implantation method on the coronary artery hemodynamics is not well understood.
arxiv
Abstract Aim Heart transplantation (HT) is frequently complicated by chronic kidney disease, of which tacrolimus‐related nephrotoxicity is an important cause. In kidney and liver transplant recipients, fast tacrolimus metabolism (defined as a low concentration‐to‐dose [C0/D] ratio), negatively affects kidney function.
Maaike R. Schagen+9 more
wiley +1 more source
Clinical and Hemodynamic Studies of Tricuspid Stenosis [PDF]
Paul N. Yu+4 more
openalex +1 more source