Results 111 to 120 of about 153,562 (315)
The role and mechanism of vascular wall cell ion channels in vascular fibrosis remodeling
ChannelsFibrosis is usually the final pathological state of many chronic inflammatory diseases and may lead to organ malfunction. Excessive deposition of extracellular matrix (ECM) molecules is a characteristic of most fibrotic tissues.
Xiaolin Zhang +5 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Functional evaluation of penile hemodynamics [PDF]
, 1988 Stief, Christian Georg +7 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT The multifunctional integration of chips with high flexibility and scalable manufacturing is crucial for enhancing chip performance, reducing chip size, and simplifying chip design. However, balancing volume, cost, flexibility, and functionality using traditional heterogeneous integration methods is challenging.
Lang Chen +7 more
wiley +1 more source
Cerebral Hemodynamics and Cognitive Function in Cirrhotic Patients with Hepatic Encephalopathy
Gastroenterology Research and Practice, 2016 Aims. To investigate cerebral hemodynamics in cirrhotic patients with HE and to observe effects of treatment in cerebral hemodynamics and correlations among ammonia, cerebral hemodynamics, and cognitive function. Methods.
Yuqing Zhou +19 more
doaj +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
Advanced Science, EarlyView.We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Advanced Science, EarlyView.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source
Percutaneous coronary intervention in coronary total occlusions: In which patients?
Revista Colombiana de Cardiología, 2016 Mario Araya, Germán Armijo
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, 2008 Hemodynamics, meaning literally "blood movement", is the study of blood flow. This machine shown here in this undated photograph checks a patient's blood flow or circulation which may be altered with a ...
core
Advanced Science, EarlyView.In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang +19 more
wiley +1 more source