Results 101 to 110 of about 857,759 (309)

A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin

, 2009
α-Hemoglobin (αHb) stabilizing protein (AHSP) is expressed in erythropoietic tissues as an accessory factor in hemoglobin synthesis. AHSP forms a specific complex with αHb and suppresses the heme-catalyzed evolution of reactive oxygen species by ...
Weiss, MJ (15531407), David Gell (14737321), Gow, A (15531404), Bendak, K (15531401), Shi, Y (5802803), Mackay, JP (15531410), Jeffrey, PD (15531398), Feng, L (15531395), Zhou, S (15524792)   +8 more
core  

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Prevalence of Anemia in Pregnant Women and Its Associated Socioeconomic Factors [PDF]

Journal of Community Health Research
Background: Anemia during pregnancy is an important public health problem, in developing countries. This community based study was conducted in Northeast India to study the prevalence of anemia along with the associated socioeconomic factors.
Gobil Thapa, Swagata Dowerah
doaj  

High Levels Of Human γ-globin Are Expressed In Adult Mice Carrying A Transgene Of The Brazilian Type Of Hereditary Persistence Of Fetal Hemoglobin (aγ -195)

, 2009
Hereditary persistence of fetal hemoglobin (HPFH) is characterized by increased levels of Hb F during adult life. Nondeletional forms of HPFH are characterized by single base mutations in the Aγ and Gγ promoters, resulting in an increase of Hb F ranging ...
Da Cunha A.F., Corra Passos L.A., Costa F.F., Gimenes A.P., Saad S.T.O., Brugnerotto A.F., Barbosa De Melo M., Finzi Corat M.A., Bodine D., Devlin E.E., Luiz A. Corrêa Passos, Anderson F. da Cunha, Passos, Luiz A Corrêa, Ana F. Brugnerotto, Saad, Sara T O, Emily E. Devlin, da Cunha, Anderson F, Bodine, David, Devlin, Emily E, Costa, Fernando F, Brugnerotto, Ana F, David Bodine, de Melo, Mônica Barbosa, Corat, Marcus A Finzi, Gimenes, Ana P, Sara T.O. Saad, Marcus A. Finzi Corat, Fernando F. Costa, Ana P. Gimenes, Mônica Barbosa de Melo   +29 more
core   +1 more source

In Situ Interfacial Assembly of Dynamic Semi‐Interpenetrating Biopolymer Networks for Robust and Mechanically Adaptive Droplet Interfaces

Advanced Functional Materials, EarlyView.
A dynamic interfacial semi‐interpenetrating polymer network is constructed by sequential assembly of β‐sheet‐rich SF and CS‐RL. The SF framework provides mechanical strength, while dynamically associated CS‐RL enables local rearrangement, allowing droplets to rapidly reconfigure without loss of interfacial integrity.
Yaping Zhang, Yujie Liu, Yikai Xu, Xunda Feng, Ling Zhang, Hongbo Zeng, Hao Liu, Xiaohui Mao   +7 more
wiley   +1 more source

Evidence for multiple differing cation binding sites on hemoglobin A and S

, 1981
Some divalent cations (at 10(-3)M concentration) have been shown to act as oxygen-linked ligands. The effect of Ca++ (only on hemoglobin S) and Zn++ (on normal hemoglobin and hemoglobin S) can be traced to a preferential binding of these cations to the ...
Santucci, R, SANTUCCI, ROBERTO, Condò, S, Antonini, E., Civalleri, L, Amiconi, G, Ascoli, F, CONDO', SAVERIO GIOVANNI, Antonini, E   +8 more
core  

Hemoglobin levels as a component of the paraneoplastic syndrome in lung cancer [PDF]

, 2012
Recently, some studies indicate that paraneoplastic syndrome may be the first sign of lung cancer and may serve in early detection of cancer. Namely, during the last ten years, an increasing importance is given to hematological paraneoplastic syndrome of
Arslanagić Rusmir, Žutić Hasan, Arslanagić Naima, Arslanagić Selma, Hasan Žutić   +4 more
core   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

POLYMORPHISM IN THE HMOX1 GENE IS ASSOCIATED WITH HIGH LEVELS OF FETAL HEMOGLOBIN IN BRAZILIAN PATIENTS WITH SICKLE CELL ANEMIA

, 2015
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)The aim of this study was to investigate the association between three polymorphisms involved in the oxidative stress pathway and fetal hemoglobin (Hb F) levels in patients with sickle cell ...
Silva, MJ, Hatzlhofer, BLD, Ananina, G, Oliveira, MB, Santos, MNN, Gil, GP, Araujo, AS, Costa, FF, Bezerra, MAC, Melo, MB   +9 more
core   +2 more sources

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source