Results 1 to 10 of about 4,194 (164)

Distribution of Abnormal Hemoglobins in Saudi Arabia: Analysis of Private Sector Laboratory Data [PDF]

Journal of Epidemiology and Global Health
Background Hemoglobinopathies are inherited blood disorders causing both a global and regional burden on health care systems and on affected individuals.
Omar M. Raslan, Osman O. Radhwi, Hadia B. Al Mahdi, Eman M. Mansory   +3 more
doaj   +2 more sources

The First Documented Case of Hb South Florida Variant in Portugal

Acta Médica Portuguesa, 2022
We present a 39-year-old male, previous smoker, with no other known cardiovascular risk factors. He was referred to Internal Medicine for study of thrombophilia, because of repeated deep vein thrombosis.
Marta Braga Martins, Luís Dias, Vânia Gomes, Céu Rodrigues   +3 more
doaj   +1 more source

Incidence of hemoglobinopathies and spatialization of newborns with sickle cell trait in Mato Grosso do Sul, Brazil [PDF]

Einstein (São Paulo), 2022
Objective To evaluate the incidence of variant hemoglobins of newborn samples from the Neonatal Screening Center in the state of Mato Grosso do Sul, Brazil, and to analyze the distribution and spatial autocorrelation of newborns with sickle cell trait.
Priscila de Matos Cândido-Bacani, Patrícia Medeiros Silva Grilo, Vanessa da Silveira Ramos, Michelly Zanchin, Indiara Correia Pereira, Josaine Sousa Palmieri Oliveira, Vitor Matheus Bacani, Edis Belini Junior   +7 more
doaj   +1 more source

Studies on Abnormal Hemoglobins [PDF]

Blood, 1952
Abstract 1. It could be demonstrated that of the three tested types of human hemoglobin—N (normal adult), S (sickle cell) and F (fetal)—only the reduced S compound shows tactoid and gel formation in sufficiently concentrated solutions. These physico-chemical phenomena may be used for the qualitative identification of S hemoglobin.
AMOZ I. CHERNOFF, KARL SINGER
openaire   +1 more source

"Pseudo-Abnormal" Hemoglobins [PDF]

Blood, 1961
Abstract Three examples of artefactual "pseudo-abnormal" hemoglobins were observed in the course of starch block electrophoresis analysis of over 400 specimens. In fresh samples from the same patients, these components were no longer demonstrable.
H A, PEARSON, J V, McCOO, S L, LEIKIN
openaire   +2 more sources

Heterozigose para hemoglobinopatias em doadores de sangue do Centro de Hemoterapia de Sergipe Heterozigosity to hemoglobinopathies in blood donors from the Hemotherapy Center in Sergipe, NE-Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2006
As hemoglobinopatias, distúrbios geneticamente determinados da hemoglobina (Hb) humana, estão presentes com freqüência elevada em várias partes do mundo, sendo que no Brasil as Hb anormais S e C são as mais prevalentes.
Wanessa L. P. Vivas, Danilo S. Rebouças, Amaury L. D. Fabbro, Rosana Cipolotti   +3 more
doaj   +1 more source

Identificação e caracterização de variantes novas e raras da hemoglobina humana Identification of characterization of novel and rare variants of human hemoglobin

Revista Brasileira de Hematologia e Hemoterapia, 2008
As anormalidades estruturais da hemoglobina estão entre as doenças genéticas mais comumente encontradas nas populações humanas. O Laboratório de Hemoglobinopatias do Departamento de Patologia Clínica da Faculdade de Ciências Médicas da Universidade ...
Elza M. Kimura, Denise M. Oliveira, Susan E. D. C. Jorge, Cristina F. Abreu, Dulcinéia M. Albuquerque, Fernando F. Costa, Maria de Fátima Sonati   +6 more
doaj   +1 more source

Interação entre Hb C [beta6(A3)Glu>Lys] e IVS II-654 (C>T) beta-talassemia no Brasil Hb C [beta6(A3)Glu>Lys] and IVS II - 654 (C>T) beta thalassemia interaction in Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2003
Thalassemias are a heterogeneous group of inherited disorders characterized by a microcytic hypochromic anemia and an imbalance in the synthesis of the globin-chains. Hb C is the second most frequently variant of hemoglobin found in Brazil.
Claudia R. Bonini-Domingos, Ana C. Bonini-Domingos, Ana R. Chinelato, Paula J. A. Zamaro, Patrícia H. O. Calderan   +4 more
doaj   +1 more source

Prevalência de hemoglobinas anormais em recém-nascidos da cidade de Natal, Rio Grande do Norte, Brasil Prevalence of abnormal hemoglobins in newborns in Natal, Rio Grande do Norte, Brazil

Cadernos de Saúde Pública, 2004
As hemoglobinopatias estão incluídas dentre as doenças hereditárias mais freqüentes nas populações humanas. Estudos realizados em diferentes regiões do Brasil têm demonstrado que as hemoglobinas anormais S e C são as mais prevalentes.
Maria Cristina Pignataro Emerenciano de Araújo, Édvis Santos Soares Serafim, Wivel Antonio Pereira de Castro Jr., Tereza Maria Dantas de Medeiros   +3 more
doaj   +1 more source

Reaction trajectory revealed by a joint analysis of protein data bank. [PDF]

PLoS ONE, 2013
Structural motions along a reaction pathway hold the secret about how a biological macromolecule functions. If each static structure were considered as a snapshot of the protein molecule in action, a large collection of structures would constitute a ...
Zhong Ren
doaj   +1 more source