Results 21 to 30 of about 441,260 (290)

γA gene repeats polymorphism for the analysis of haplotypes of abnormal hemoglobins

Thalassemia Reports, 2014
Aim of this study was to analyze γ A gene repeat polymorphism for the analysis of haplotypes of hemoglobin (Hb) variants such as Hb S, Hb D-Punjab, Hb O-Arab. Sickle cell cases had mainly Benin and Arab/Indian haplotype.
Nejat Akar, Kadir Sipahi, Ece Akar, Erkan Yilmaz   +3 more
doaj   +1 more source

The first Chinese case of unstable Hemoglobin Santa Ana detected by capillary electrophoresis: a case report and literature review

Hematology, 2022
Hemoglobin Santa Ana [β88(F4)Leu→Pro (CTG > CCG) HBB: c.266T > C] is an unstable hemoglobin variant characterized by a substitution of the amino acid leucine by proline at the 88th position of the β-globin chain.
Li Du, Danqing Qin, Jicheng Wang, Cuize Yao, Juan Zhu, Hao Guo, Tenglong Yuan, Jie Liang, Aihua Yin   +8 more
doaj   +1 more source

STUDIES ON ABNORMAL HEMOGLOBIN

Nihon Naika Gakkai Zasshi, 1967
本邦では1957年ごろより異常血色素の本格的検索がはじめられたが,著者は戦後わが国に残された混血児達により,従来本邦に存在しなかつた異常血色素の遺伝因子が導入される可能性を考え,その実態を明らかにせんとして混血児179名について異常血色素の検索を行ない,また同時に東京,神奈川在住本邦人3000余名についても異常血色素の検索を行なつた.その結果,本邦人3000余名中よりは1例も異常血色素を確認できなかつたが,混血児179名中よりは2例に異常血色素を確認した.この比率は約1.1%である.
openaire   +2 more sources

The primary structure of three hemoglobin chains from the indigo snake (Drymarchon corais erebennus, Serpentes): First evidence for αD chains and two β chain types in snakes [PDF]

, 2002
The hemoglobin of the indigo snake (Drymarchon corais erebennus, Colubrinae) consists of two components, HbA and HbD, in the ratio of 1:1. They differ in both their alpha and beta chains.
Kleinschmidt, T., Gorr, T., Stoeckelhuber, M.   +2 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Structure and function of tetrameric hemoglobins and their mutants at a molecular and cellular level. [PDF]

, 2011
The present Ph.D. thesis has focused on tetrameric hemoglobins (Hbs), both recombinant and natural, both from human origin and Antarctic fish, using a multidisciplinary approach based on spectroscopic, crystallographic and computational techniques.
Balsamo, Anna
core   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

A comparative study of norethisterone and combined oral contraceptive pill in the treatment of dysfunctional uterine bleeding

CHRISMED Journal of Health and Research, 2019
Background: A significant percentage of women in India suffer from dysfunctional uterine bleeding (DUB), which has a negative impact on physical and social life.
Sayantan Sen, Tapan Kumar Mandal, Arijit Dutta, Himel Mondal, Tufan Khalua   +4 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Structure and Reactivity of Hexacoordinate Hemoglobins [PDF]

, 2010
The heme prosthetic group in hemoglobins is most often attached to the globin through coordination of either one or two histidine side chains. Those proteins with one histidine coordinating the heme iron are called “pentacoordinate” hemoglobins, a group ...
Mark S. Hargrove, Storz, Jay F., Jay F. Storz, Hargrove, Mark S., Kakar, Smita, Smita Kakar, Marian Fabian, Fabian, Marian, Hoffmann, Federico G., Federico G. Hoffman   +9 more
core   +1 more source