Results 1 to 10 of about 11,475 (240)
Hemoglobinopathy SD presenting as Hemoglobinopathy SS
Medicina, 2017 This case report shows the interaction of hemoglobin (Hb) S with Hb D. in a child previously diagnosed with sickle cell anemia based on the Hb electrophoretic migration pattern in alkaline pH.
Sonia Maria Lissa +4 more
doaj +3 more sources
An overview of complications associated with deferoxamine therapy in thalassemia [PDF]
Journal of Nephropharmacology, 2021 Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei +5 more
doaj +1 more source
Frontiers in Medicine, 2021 This systematic review aimed to provide an overview of the clinical profile and outcome of COVID-19 infection in patients with hemoglobinopathy. The rate of COVID-19 mortality and its predictors were also identified.
Jun Xin Lee +3 more
doaj +1 more source
Vnitřní lékařství, 2018 This article summarize molecular-genetic basis of hemoglobinopathies, their classification and phenotypic manifestations. The description of individual subgroups is supplemented with a case reports of patients diagnosed in the Czech population. This paper provides an overview of 14 types of α-thalassemic mutations, 34 β-thalassemic alleles, 4 δβ ...
Karel, Indrák +6 more
openaire +2 more sources
Scientific Reports, 2022 Ferritin is frequently used to screen some dire consequences of iron overload in β-thalassemia patients. The study aimed to define the best cutoff point of ferritin to screen for cardiac and liver hemosiderosis in these cases.
Hadi Darvishi-Khezri +7 more
doaj +1 more source
Turkish Journal of Hematology, 2018 Objective: The Turkish Society of Pediatric Hematology set up a National Hemoglobinopathy Registry to demonstrate the demographic and disease characteristics of patients and assess the efficacy of a hemoglobinopathy control program (HCP) over 10 years in
Yeşim Aydınok +35 more
doaj +1 more source
Distribution of Hemoglobinopathy in Nepalese Population
Journal of Nepal Health Research Council, 2020 Background: Sickle cell and thalassemia are the inherited disorders of globin chain synthesis, and are the most common monogenic disease worldwide. This study aims to find the distribution of hemoglobinopathies (sickle cell and thalassemia) cases in ...
Rekha Manandhar Shrestha +5 more
doaj +1 more source
Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]
, 2017 Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Ali, Bassam R. +11 more
core +5 more sources
Early Screening of Hemoglobinopathy in Indonesia Using Erythrocyte Indices
Indonesian Biomedical Journal, 2017 BACKGROUND: The mutation spectrums of hemoglobinopathy are different among populations that yield a different result of erythrocyte indices. Calculation of erythrocyte indices with some formula has been reported to differentiate between hemoglobinopathy ...
Yenny Surjawan +3 more
doaj +1 more source
Time to Do Something for Vitamin D Deficiency; A Review
Journal of Pediatrics Review, 2015 Context: Vitamin D deficiency is a common nutritional disorder in Iran. Vitamin D is an essential health factor from birth onward. This study was conducted to summarize epidemiologic researches regarding vitamin D deficiency in different parts of the ...
Mehrnoush Kosaryan +3 more
doaj +3 more sources