Results 221 to 230 of about 857,759 (309)

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

Supramolecular Allostery Achieves Tunable Luminescence Aromatic Bridged Phenothiazine Noncovalent Frameworks

Advanced Science, EarlyView.
Tunable luminescent supramolecular organic framework enabled by multiple allosteric effects, composed of a tetracation vinylphenylpyridinium‐modified aromatic‐bridged phenothiazine guest and cucurbit[8]uril, not only exhibits unique guest oxidation‐driven NIR luminescence blue‐shift and effectively enhances the quantum yield by 46‐fold to 22.2% but ...
Xinping Lu, Jianchong Chen, Jie Yu
wiley   +1 more source

Real-world use of pegylated erythropoietin in CKD-related anemia: an Indian modified Delphi consensus. [PDF]

Front Nephrol
Kher V, Kothari J, Kumar J, Srinivasa S, Kedlaya P, M S, Bhat R, Nair R, Hm M, Sharma R, Sinha VK, C G S, Sharma JK, Macdougall IC.   +13 more
europepmc   +1 more source

Hemoglobin

, 2018
Kamarudin K., C-Khai L., Azma R.Z., Othman A., Alauddin H., Jalil N., Razak N.-F., Abdul Latiff Z., Alias H., Ithnin A., Koh-Xuan-Rong D., Ismail E., Loong T.Y.   +12 more
core   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Validation of Non-Invasive Hemoglobin Measurement and Its Utility for Anemia Screening in Pregnancy: A Cross-Sectional Diagnostic Accuracy Study. [PDF]

Diagnostics (Basel)
Luewan S, Wongyai M, Tongsong T.
europepmc   +1 more source

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

Advanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo, Xingxing Li, Chenjun Zou, Chao Zheng, Xiaohong Wu, Xuechao Lu, Jiaying Yan, Junfang Zhang, Xiaoyan Luo, Shiwei Ye, Dongsheng Zhou   +10 more
wiley   +1 more source

Association Between Hemoglobin Levels and Hemorrhagic Stroke Severity and In-Hospital Outcomes: A Multi-Centre Cross-Sectional Study on Recovery and Prognosis in Pakistan. [PDF]

Brain Behav
Johar A, Ahmad A, Akhter J, Aftab W, Ali A, Jamal MA, Jawad M, Noor R, Majeed H, Khanm A, Kamil KA.   +10 more
europepmc   +1 more source