Results 281 to 290 of about 1,338,396 (378)

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

open access: yesAdvanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu   +18 more
wiley   +1 more source

IsdB-dependent hemoglobin binding is required for acquisition of heme by Staphylococcus aureus.

open access: yesJournal of Infectious Diseases, 2014
Gleb Pishchany   +7 more
semanticscholar   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

open access: yesAdvanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu   +18 more
wiley   +1 more source

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Jian Xu   +9 more
semanticscholar   +1 more source

Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy

open access: yesAdvanced Science, EarlyView.
Resting‐state fMRI captures intrinsic brain activity, yet the physical significance of latency structures remains unclear. In this study, the spatiotemporal properties of fMRI‐derived latency structures are examined by linking them to biophysical model‐based neural functions, intrinsic neural timescales, and functional gradients.
Hyoungshin Choi   +5 more
wiley   +1 more source

Two studies of Tsarang village, Upper Mustang Nepal with different results. [PDF]

open access: yesJ Physiol Anthropol
Craig SR   +4 more
europepmc   +1 more source

A Hypoxia‐Responsive Single‐Atom Sonozyme for Targeted Sonocatalytic Therapy in Alleviating Atherosclerotic Plaque

open access: yesAdvanced Science, EarlyView.
A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen   +14 more
wiley   +1 more source

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