Results 21 to 30 of about 826,020 (365)

Molecular Dynamics Simulations Indicate that Deoxyhemoglobin, Oxyhemoglobin, Carboxyhemoglobin, and Glycated Hemoglobin under Compression and Shear Exhibit an Anisotropic Mechanical Behavior [PDF]

Journal of Biomolecular Structure and Dynamics, 2017, 2017
We developed a new mechanical model for determining the compression and shear mechanical behavior of four different hemoglobin structures. Previous studies on hemoglobin structures have focused primarily on overall mechanical behavior; however, this study investigates the mechanical behavior of hemoglobin, a major constituent of red blood cells (RBCs),
arxiv   +1 more source

Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting

Evolutionary Bioinformatics, 2015
Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors.
Gisele Cristine De Souza Carrocini, Larissa Paola Rodrigues Venancio, Claudia Regina Bonini-Domingos   +2 more
doaj   +1 more source

Laboratory Test Predictors for Major Bleeding in Elderly (≥80 Years) Patients With Nonvalvular Atrial Fibrillation Treated With Edoxaban 15 mg: Sub‐Analysis of the ELDERCARE‐AF Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background We investigated the predictors related to major bleeding events during treatment with edoxaban 15 mg in patients aged ≥80 years with nonvalvular atrial fibrillation and high bleeding risk, for whom standard oral anticoagulants are ...
Takeshi Mikami, Kagami Hirabayashi, Keisuke Okawa, Tetsuo Betsuyaku, Saori Watanabe, Yuki Imamura, Kimihiko Tanizawa, Takuya Hayashi, Masaharu Akao, Takeshi Yamashita, Ken Okumura   +10 more
doaj   +1 more source

Cross-sectional and longitudinal association between hemoglobin concentration and hypertension

Medicine, 2016
We investigated the cross-sectional and longitudinal associations between hemoglobin concentration and hypertension in a Korean population. Between 2006 and 2013, we examined 4899 participants with mean age of 56.6 years (range 35–88 years) from a rural ...
Na Hyun Kim, Ju-Mi Lee, H. Kim, J. Lee, Hyungseon Yeom, J. H. Lee, I. Suh   +6 more
semanticscholar   +1 more source

Influence of periodontal infection as a possible risk factor for preterm low birth weight

Journal of Pharmacy and Bioallied Sciences, 2020
Background: There is emerging interest and increasing amount of evidence that support the interrelationship between periodontitis and systemic conditions.
Rajesh K Thakur, Bipin K Yadav, Rafat Sultana, Shakeb K Afridi, Debasmita Das, Sheetal K Sahoo   +5 more
doaj   +1 more source

Association of In‐Hospital Hemoglobin Drop With Decreased Myocardial Salvage and Increased Long‐Term Mortality in Patients With Acute ST‐Segment–Elevation Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Anemia and blood loss occur often in patients with ST‐segment–elevation myocardial infarction (STEMI). In‐hospital hemoglobin drop is associated with 1‐year mortality in patients with acute coronary syndrome.
Alexander Dutsch, Christian Graesser, Felix Voll, Sophie Novacek, Robert Eggerstedt, Nicolás López Armbruster, Karl‐Ludwig Laugwitz, Salvatore Cassese, Heribert Schunkert, Gjin Ndrepepa, Adnan Kastrati, Thorsten Kessler, Hendrik B. Sager   +12 more
doaj   +1 more source

Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells

Science, 2018
A CRISPR screen for RBC regulators Hemoglobin in red blood cells (RBCs) carries oxygen to the tissues. Sickle cell disease is an inherited condition that involves abnormal hemoglobin.
Jeremy D. Grevet, Xianjiang Lan, Nicole Hamagami, Christopher R. Edwards, Laavanya Sankaranarayanan, X. Ji, Saurabh K. Bhardwaj, Carolyne J. Face, D. Posocco, O. Abdulmalik, C. Keller, B. Giardine, Simone Sidoli, B. A. Garcia, S. Chou, S. Liebhaber, R. Hardison, Junwei Shi, G. Blobel   +18 more
semanticscholar   +1 more source

Effectiveness of intravenous ferric carboxymaltose in improving hemoglobin level among postpartum women with moderate-to-severe anemia at a secondary care hospital in Faridabad, Haryana – An interventional study

Indian Journal of Public Health, 2020
Background: Postpartum anemia is associated with postpartum anxiety, depression, poor cognitive interaction, and delayed infant development. Oral iron is the currently recommended therapy but is associated with gastrointestinal complaints and poor ...
Shashi Kant, Ravneet Kaur, Farhad Ahamed, Archana Singh, Sumit Malhotra, Rakesh Kumar   +5 more
doaj   +1 more source

Epidemiology of malaria and anemia in high and low malaria-endemic North-Eastern districts of India

Frontiers in Public Health, 2022
Anemia and malaria are the two major public health problems that lead to substantial morbidity and mortality. Malaria infection destroys erythrocytes, resulting in low hemoglobin (Hb) levels known as anemia.
Hari Shankar, Hari Shankar, Mrigendra Pal Singh, Syed Shah Areeb Hussain, Sobhan Phookan, Kuldeep Singh, Neelima Mishra   +6 more
doaj   +1 more source

U-shaped curve for risk associated with maternal hemoglobin, iron status, or iron supplementation.

American Journal of Clinical Nutrition, 2017
Both iron deficiency (ID) and excess can lead to impaired health status. There is substantial evidence of a U-shaped curve between the risk of adverse birth outcomes and maternal hemoglobin concentrations during pregnancy; however, it is unclear whether ...
K. Dewey, Brietta M. Oaks
semanticscholar   +1 more source