Results 21 to 30 of about 857,759 (309)

Successful Treatment of a Child with Hemoglobin Hammersmith with Hematopoietic Stem Cell Transplantation

, 2023
Hemoglobin (Hb) Hammersmith, formed by serine substitution for phenylalanine at residue 42 in the beta-globin chain, is a very rare variant of unstable hemoglobin with low oxygen affinity. For patients with hemoglobinopathies, it is well-established that
Özek, Gülcihan, Gülcihan Özek, Türedi Yıldırım, Ayşen, Türkmen, Hulya, Durmaz, Burak, Gülen, Hüseyin, Hülya Türkmen, Ayşen Türedi Yıldırım, Oymak, Yeşim, Burak Durmaz, Yeşim Oymak, Karaca, Emin, Emin Karaca, Hüseyin Gülen, YILDIRIM, AYŞEN, Yıldırım A.T., Gülen H., Türkmen H., Durmaz B., Karaca E., DURMAZ, MEHMET BURAK, Özek G., Oymak Y.   +22 more
core   +1 more source

Blood erythrocyte indices in rats under conditions of acetaminophen-induced toxic injury against the background of alimentary protein deficiency

Medičnì Perspektivi, 2022
Despite the available information on variations in the erythrocyte chain of homeostasis under the conditions of drug-induced toxic damage, the question of the biochemical characteristics of erythrocytes in the expose of toxic doses of paracetamol on the
H.P. Kopylchuk, I.M. Nykolaichuk
doaj   +1 more source

The Role of Reticulocyte Hemoglobin Content in Diagnosing Iron Deficiency in Childhood Cancer

Indian Journal of Medical and Paediatric Oncology
Background The prevalence of iron deficiency (ID) and iron deficiency anemia (IDA) in children with cancer is not well studied. The detection of ID and IDA using sensitive laboratory tools may facilitate early diagnosis and treatment in this ...
Murti Andriastuti, Anisa Dwi Fathinasari, Afifa Fahriyani, Kanthi Soraca Widiatmika, Khansa Salsabila, Fitri Primacakti   +5 more
doaj   +1 more source

Chemotherapeutic Response and Survival for Patients With an Anal Squamous Cell Carcinoma and Low Hemoglobin Levels [PDF]

Annals of Coloproctology, 2018
Purpose Anemia is associated with poor treatment results for a variety of cancers. The effect of low hemoglobin levels on long-term outcomes after the treatment of patients with an anal squamous cell carcinoma (SCC) remains unclear. For that reason, this
Ali Zain Naqvi, Esther Platt, Maki Jitsumura, Martyn Evans, Mark Coleman, Sebastian Smolarek   +5 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Energy Metabolism and Aerobic Respiratory Chain of Vitreoscilla sp. C1: Comparison with β-Proteobacteria

Microbiology Research
As the source of the first reported class of non-mammalian hemoglobin, Vitreoscilla sp. C1 is a historically important microorganism that has offered important clues to understanding how bacteria can thrive at low oxygen tension, with potential ...
Paul T. Nguyen, Yuyao Hu, Anne Caroline Mascarenhas dos Santos, Pingdong Liang, Benjamin C. Stark, Karina Tuz, Oscar Juárez   +6 more
doaj   +1 more source

Measuring forces between protein fibers by microscopy [PDF]

, 2005
We propose a general scheme for measuring the attraction between mechanically frustrated semiflexible fibers by measuring their thermal fluctuations and shape.
Wang, J. C., Taylor, Matthew S., Jones, C. W. (Christopher W.), Briehl, R. W.   +3 more
core   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

HBB FSC 36-37 (-T) Gene Mutation Detection in Carriers of Thalassemia Minor Using High Resolution Melting Analysis [PDF]

Journal of Genetic Resources, 2018
Beta-thalassemia is one of the most common autosomal recessive disorders in the world population resulting from over 200 different mutations of HBB gene.
Zahra-Sadat Asadi, Fatemeh Akhoundi, Mansour Salehi, Parvaneh Nikpour, Modjtaba Emadi-Baygi   +4 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source