Results 281 to 290 of about 23,660,822 (374)

MiR-223-3p regulates erythropoiesis by targeting TGFBR3/Smad signaling pathway in hemoglobin H-Constant Spring disease. [PDF]

Ann Med
Lan L, Wang X, Zhang S, Zeng D, Mo L, Feng Q, Li J, Zhu C.   +7 more
europepmc   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Clinical evaluation of SafeCEC^® one-way valve in hemolysis during CPB: Pilot study. [PDF]

J Extra Corpor Technol
Coutinho HMDR, Coutinho JHSA, Torres JH, Casanova RM, Kikuta G, Reis EE.   +5 more
europepmc   +1 more source

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

Advanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao, Xiaolei Cheng, Rongbin Lv, Dianshui Sun, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li   +9 more
wiley   +1 more source

Linkage Between Hemoglobin to High Density Lipoprotein-Cholesterol Ratio and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Nationally Representative Study. [PDF]

Clin Transl Sci
Liu Z, Yin H, Li W, Zhang J.
europepmc   +1 more source

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei, Yichun Pan, Jie Zhai, Tongqing Li, Yuxin Zhou, Sheyu Zhang, Juan Wei, Qian Hu, Xueying Liu, Lu Guo, Weizhu Wu, Yong Wei, Qin Wu, Weihong Tan   +13 more
wiley   +1 more source

Relationship of hyperemesis gravidarum with platelet crit, hemoglobin-to-red cell distribution width ratio, and neutrophil-to-lymphocyte ratio. [PDF]

Rev Assoc Med Bras (1992)
Uçkan K, Başkiran Y, Çeleğen İ.
europepmc   +1 more source

An Anisotropic Gold‐Palladium Heterostructured Nanosystem for Synergistically Overcoming Radioresistance and Enhancing Melanoma Radioimmunotherapy

Advanced Science, EarlyView.
A multifunctional anisotropic Au‐Pd heterostructured nanosystem is developed that incorporates a plasmonically enhanced Au‐Pd core, with a shell composed of a biodegradable, Mn‐doped targeting peptide. The nanosystem integrates photothermal, radiotherapeutic, and immunomodulatory functions.
Cheng Chen, Yuqi Huang, Wandong Wang, Minghao Chao, Weiguo Sun, Yinghui Kong, Guan Jiang, Yong Gao, Fenglei Gao   +8 more
wiley   +1 more source

The Prevalence of Vitamin B12, Hemoglobin, and Ferritin Deficiency in Patients with Morbid Obesity and Changes in their Blood Levels after Bariatric Surgery. [PDF]

Int J Prev Med
Soheilipour F, Nematollahi S, Mottaghi A, Ordooei M, Shahrzad MK, Alaei M, Bahoush G, Ebrahimian M, Eskandari D.   +8 more
europepmc   +1 more source

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

Advanced Science, EarlyView.
A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan, Cheng‐Hung Luo, Wen‐Ling Lin, Liu‐Chun Wang, Divinah Manoharan, Po‐Ya Chang, Hwo‐Shuenn Sheu, Chen‐Hao Yeh, Chia‐Jui Yen, Chen‐Sheng Yeh   +9 more
wiley   +1 more source