Results 311 to 320 of about 23,660,822 (374)

Glucose‐Responsive and Analgesic Gel for Diabetic Subcutaneous Abscess Treatment by Simultaneously Boosting Photodynamic Therapy and Relieving Hypoxia

Advanced Science, EarlyView.
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang, Honglin An, Jianfeng Chu, Shiqi Ke, Jing Ke, Yiman Qiu, Jieping Zhang, Hanqi Zhu, Jiahui Lin, Minguang Yang, Dongliang Yang, Xuejiao Song, Weilin Liu   +12 more
wiley   +1 more source

Explainable artificial intelligence driven insights into smoking prediction using machine learning and clinical parameters. [PDF]

Sci Rep
Aishwarya S, Siddalingaswamy PC, Chadaga K.   +2 more
europepmc   +1 more source

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

Advanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang, Xiangqin Ou, Jingyi Lin, Xiaofei Luo, Jiashun Zhou, Xingyue Zhou, Peihua Zhao, Li Liu, Ziran Zhao, Ying Zhou, Guanwei Fan, Lifeng Han, Xiumei Gao   +12 more
wiley   +1 more source

Remote Photoplethysmography Technology for Blood Pressure and Hemoglobin Level Assessment in the Preoperative Assessment Setting: Algorithm Development Study. [PDF]

JMIR Form Res
Tan SYL, Chai JX, Choi M, Javaid U, Tan BPY, Chow BSY, Abdullah HR.   +6 more
europepmc   +1 more source

Advanced Cancer Immunotherapy via SMARCAL1 Blockade Using a Glucose‐Responsive CRISPR Nanovaccine

Advanced Science, EarlyView.
A glucose‐catalyzed chemodynamic strategy is proposed to activate therapeutic genome editing of SMARCAL1to improve cancer immunotherapy. This innovative design featuring Fenton reaction activity and glucose consumption ability, not only effectively synergizes to activate the cGAS‐STING pathway but also inhibits the opposing functions of interferon by ...
Yuwei Li, Yuanyi Zhang, Chenchen Li, Guoping Chen, Pir Muhammad, Yonghong Yao, Lifang Gao, Zhigang Liu, Yanli Wang   +8 more
wiley   +1 more source

Optimizing blood management in burn surgery: a meta-analysis of tranexamic acid vs. placebo. [PDF]

BMC Surg
Khalafallah MA, Elsead JA, Aboud FA, Koraim BM, Elhois IS.   +4 more
europepmc   +1 more source

A Promising Point‐of‐Care Testing Strategy: Ultrasmooth Gold Nanogroove Arrays Biosensor Combined with Initial Rate Analysis

Advanced Science, EarlyView.
This work reports a nanoplasmonic biosensing platform with exceptional surface sensitivity (0.618 nm nm−1, Δn = 0.117 nmol) and narrow linewidth (≈20 nm) under normal incidence. By integrating a miscellaneous‐protein strategy with initial rate analysis (IRA), this sensor can detect 1 ng mL−1 of AFP in serum with a broad linear range (1–104 ng mL−1 ...
Yi Liu, Shan Xing, Zhan Si, Kai He, Manchun Zheng, Yang Shen, Chongjun Jin   +6 more
wiley   +1 more source

Vitamin B6 Deficiency May Not Always Present As Microcytic Hypochromic Anemia. [PDF]

Cureus
Nakao S, Nakaseko C, Ishii T, Terai K, Shimizu N.   +4 more
europepmc   +1 more source

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

Advanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong, Zhiyuan Du, Tiantian Gong, Yu Wang, Chenchen Yin, Bosi Sun, Zijia Liu, Lianru Chen, Zibin Liao, Wenxin Wang, Tianjiao Zhao, Yifei Wang, Ying Dong, Kexin Wang, Mengru Ma, Weijun Li, Jiacheng Li, Haodong Li, Congcong Lin, Ying Zhang, Yu Liu, Xin Liu, Tao Ban, Hongxia Bao, Ying Zhang, Yang Zhang, Zheng Li, Lei Jiao   +27 more
wiley   +1 more source

Significance of hemoglobin and hematocrit changes in predicting patient survival and efficacy of neoadjuvant chemotherapy for advanced gastric cancer. [PDF]

World J Gastrointest Oncol
Qiu TH, Wen HY, Huang YL.
europepmc   +1 more source