Comment on "Twisted Protein Aggregates and Disease: The Stability of Sickle Hemoglobin Fibers" [PDF]
arXiv, 2010 Aggregates of twisted protein fibers, such as sickle hemoglobin and actin, are important examples of biopolymers in which elastic interactions play a crucial role in determining the (metastable) bundle radii. Here, we present a corrected version of analysis on the stability of sickle hemoglobin fibers using the classic nucleation theory.
arxiv
Gynecology Obstetrics & Reproductive MedicineObjective: Our aim in this study is to examine the relationship of hemoglobin A1c (HbA1c) and fasting glucose with the stage, grade and histological type of cancer and its value in predicting the prognosis of endometrial cancer in diabetic endometrial ...
Ayse Rabia Senkaya +3 more
doaj +1 more source
Backswimmer Inspired Miniature Robot with Buoyancy Auto-Regulation through Controlled Nucleation and Release of Microbubbles [PDF]
arXiv, 2021 The backswimmer fly is an aquatic insect, capable of regulating its buoyancy underwater. Its abdomen is covered with hemoglobin cells, used to bind and release oxygen, reversibly. Upon entering water, the fly entraps an air bubble in a superhydrophobic hairy structure on its abdomen for respiration.
arxiv
Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]
, 2017 Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Chondrou, Vasiliki +11 more
core +4 more sources
Rapid point-of-care Hemoglobin measurement through low-cost optics and Convolutional Neural Network based validation [PDF]
arXiv, 2017 A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin detectors which rely on micro cuvettes and dry chemistry. Any particulates (e.g.
arxiv
Single-cell measurement of red blood cell oxygen affinity [PDF]
arXiv, 2015 Oxygen is transported throughout the body by hemoglobin in red blood cells. While the oxygen affinity of blood is well understood and is routinely assessed in patients by pulse oximetry, variability at the single-cell level has not been previously measured.
arxiv
Magnetic mechanism for the biological functioning of hemoglobin [PDF]
arXiv, 2019 The role of magnetism in the biological functioning of hemoglobin has been debated since its discovery by Pauling and Coryell in 1936. The hemoglobin molecule contains four heme groups each having a porphyrin layer with a Fe ion at the center. Here, we present combined density-functional theory and quantum Monte Carlo calculations for an effective ...
arxiv
Simple Model of Sickle Hemogloblin [PDF]
, 2005 A microscopic model is proposed for the interactions between sickle hemoglobin molecules based on information from the protein data bank. A Monte Carlo simulation of a simplified two patch model is carried out, with the goal of understanding fiber formation.
arxiv +1 more source
Conformational studies of various hemoglobins by natural-abundance 13C NMR spectroscopy [PDF]
, 1972 Studies of variously liganded hemoglobins (both from human and rabbit) by natural-abundance 13C NMR spectroscopy have revealed apparent conformational differences that have been interpreted on the basis of two quaternary structures for the α2ß2 tetramer,
Moon, R. B., Richards, J. H.
core +1 more source
Vascular risk factors and diabetic neuropathy [PDF]
, 2005 Background: Other than glycemic control, there are no treatments for diabetic neuropathy. Thus, identifying potentially modifiable risk factors for neuropathy is crucial.
Chaturvedi, N. +7 more
core +1 more source