Results 161 to 170 of about 20,445,864 (375)

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

Evaluation of some Biochemical and Hematological Parameters in Patients with Chronic Kidney Disease

open access: yesمجلة كلية الطب
Background: Chronic kidney disease is a condition that results from an indefinite change in the structure and function of the kidneys. A slow, steady progression characterizes it and is irreversible.
Hadeel T. AlAni, Makarim Q. Al-Lami
doaj   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Hb M-Saskatoon: An unusual cause of cyanosis in a Spanish child

open access: yesPediatric Hematology Oncology Journal, 2019
Pulse oximetry in a 15-month-old boy with cyanosis revealed low oxygen saturation (SpO2 60%) with normal echocardiography findings. Arterial blood gas analysis showed normal PaO2, low hemoglobin oxygen saturation, and high methemoglobin level.
Marina García-Morin   +6 more
doaj  

Clinical and Necropsy Findings in Hemoglobin C Disease [PDF]

open access: bronze, 1957
Wallace N. Jensen   +2 more
openalex   +1 more source

Hemoglobin Hasharon (α247 his(CD5)β2): a hemoglobin found in low concentration

open access: yes, 1969
: Hemoglobin Hasharon (alpha(2) (47 his)(CD5)beta(2)) was found to comprise only 16-19% of hemolysates of carriers. These heterozygotes appeared to have mild, compensated, hemolytic anemia.
S. Charache, A. Mondzac, U. Gessner
semanticscholar   +1 more source

Microarray Analysis of PBMC after Plasmodium falciparum Infection: Molecular Insights into Disease Pathogenesis [PDF]

open access: yes, 2011
Our laboratory’s previous microarray analysis of subjects with Plasmodium falciparum revealed up-regulation of Toll-like receptor, NF-kB, TNF-α, IFN-γ, IL-1β, p38 MAPK, and MHC molecules.
Alan Scott   +5 more
core   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Pathogenesis of Hemolytic Anemia in Homozygous Hemoglobin C Disease* [PDF]

open access: bronze, 1967
Samuel Charache   +4 more
openalex   +1 more source

HUBUNGAN TINGKAT KECUKUPAN BESI DENGAN KADAR HEMOGLOBIN PADA REMAJA HAMIL USIA 15-19 TAHUN (Studi di Kelurahan Rowosari Kota Semarang) [PDF]

open access: yes, 2016
Kehamilan pada usia remaja berisiko lebih tinggi terhadap kejadian anemia karena kebutuhan kehamilan dan pertumbuhannya. Remaja putri sering membatasi asupan makanan sehingga risiko anemia semakin meningkat.
PANGESTIKA, PUTRI SRIWULANDARI
core  

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