Results 161 to 170 of about 20,445,864 (375)
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo+11 more
wiley +1 more source
Evaluation of some Biochemical and Hematological Parameters in Patients with Chronic Kidney Disease
Background: Chronic kidney disease is a condition that results from an indefinite change in the structure and function of the kidneys. A slow, steady progression characterizes it and is irreversible.
Hadeel T. AlAni, Makarim Q. Al-Lami
doaj +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Hb M-Saskatoon: An unusual cause of cyanosis in a Spanish child
Pulse oximetry in a 15-month-old boy with cyanosis revealed low oxygen saturation (SpO2 60%) with normal echocardiography findings. Arterial blood gas analysis showed normal PaO2, low hemoglobin oxygen saturation, and high methemoglobin level.
Marina García-Morin+6 more
doaj
Clinical and Necropsy Findings in Hemoglobin C Disease [PDF]
Wallace N. Jensen+2 more
openalex +1 more source
Hemoglobin Hasharon (α247 his(CD5)β2): a hemoglobin found in low concentration
: Hemoglobin Hasharon (alpha(2) (47 his)(CD5)beta(2)) was found to comprise only 16-19% of hemolysates of carriers. These heterozygotes appeared to have mild, compensated, hemolytic anemia.
S. Charache, A. Mondzac, U. Gessner
semanticscholar +1 more source
Microarray Analysis of PBMC after Plasmodium falciparum Infection: Molecular Insights into Disease Pathogenesis [PDF]
Our laboratory’s previous microarray analysis of subjects with Plasmodium falciparum revealed up-regulation of Toll-like receptor, NF-kB, TNF-α, IFN-γ, IL-1β, p38 MAPK, and MHC molecules.
Alan Scott+5 more
core +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Pathogenesis of Hemolytic Anemia in Homozygous Hemoglobin C Disease* [PDF]
Samuel Charache+4 more
openalex +1 more source
HUBUNGAN TINGKAT KECUKUPAN BESI DENGAN KADAR HEMOGLOBIN PADA REMAJA HAMIL USIA 15-19 TAHUN (Studi di Kelurahan Rowosari Kota Semarang) [PDF]
Kehamilan pada usia remaja berisiko lebih tinggi terhadap kejadian anemia karena kebutuhan kehamilan dan pertumbuhannya. Remaja putri sering membatasi asupan makanan sehingga risiko anemia semakin meningkat.
PANGESTIKA, PUTRI SRIWULANDARI
core