Results 261 to 270 of about 20,445,864 (375)

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Identification and mitigation of blood's interference with the antimicrobial activity of AgNbO3 particles. [PDF]

PLoS One
Talebpour C, Fani F, Ouellette M, Fairfax M, Alamdari H, Salimnia H.   +5 more
europepmc   +1 more source

Hemoglobin S and C Heterozygosity Enhances Neither the Magnitude nor Breadth of Antibody Responses to a Diverse Array of Plasmodium falciparum Antigens [PDF]

, 2011
Xiaolin Tan, Boubacar Traoré, Kassoum Kayentao, Aissata Ongoïba, Safiatou Doumbo, Michael Waisberg, Ogobara K. Doumbo, Philip L. Felgner, Rick M. Fairhurst, Peter D. Crompton   +9 more
openalex   +1 more source

Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand

Advanced Science, EarlyView.
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li, Hwan D. Kim, Allen C. Luo, Liyan Gong, Yonglin Zhu, Chin Nien Lee, Xuechong Hong, Christopher L. Sudduth, Michal Ad, Young‐Hyeon An, Mihn Jeong Park, Do‐Gyoon Kim, Arin K. Greene, Bonnie L. Padwa, Nathaniel S. Hwang, Ruei‐Zeng Lin, Juan M. Melero‐Martin   +16 more
wiley   +1 more source

Predictive Value of Dynamic Changes in Hemoglobin Levels During Early Pregnancy for the Development of Anemia During Pregnancy. [PDF]

Int J Womens Health
Liu L, Li X.
europepmc   +1 more source

Allen A, Fisher C, Premawardhena A, et al. Adaptation to anemia in hemoglobin E-β thalassemia. Blood. 2010;116(24):5368-5370. [PDF]

, 2011

openalex   +1 more source

RIG‐I‐Inducing Small Molecules Potently Inhibit HMA‐Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Advanced Science, EarlyView.
This study reveals a novel mechanism of resistance to DNA hypomethylating agents (HMAs) in acute myeloid leukemia (AML), and identifies all‐trans retinoic acid (ATRA) and tamibarotene (TAM) as potent agents that overcome HMA resistance by reactivating the interferon anticancer immune response. The findings offer promising therapeutic strategies for HMA‐
Xueqin Chen, Jiaqi Wu, Yuntong Li, Jiayu Huang, Xiangqin Weng, Jiale Wu, Shujun Xiao, Huaxin Song, Zhengyuan Wang, Ni Yan, Fangfang Shi, Derun Zheng, Kai Tan, Hesong Zhang, Jingyi Cui, Wen Wu, Wei Wu, Sujiang Zhang, Min Lu   +18 more
wiley   +1 more source

Hemoglobins S and C Interfere with Actin Remodeling in Plasmodium falciparum –Infected Erythrocytes [PDF]

, 2011
Marek Cyrklaff, Cecília P. Sanchez, Nicole Kilian, Cyrille Bisseyé, Jacques Simporé, Friedrich Frischknecht, Michael Lanzer   +6 more
openalex   +1 more source

Physical Activity and Reduced Risk of Cardiovascular Events: Potential Mediating Mechanisms

Circulation, 2007
S. Mora, N. Cook, J. Buring, P. Ridker, I. Lee   +4 more
semanticscholar   +1 more source

An Injectable BMP‐2‐Releasing Porous Hydrogel Regulating the Paracrine Effects of ADSCs Promotes Tendon‐to‐Bone Healing in Rotator Cuff Repair

Advanced Science, EarlyView.
This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan, Xiaomei Dai, Yuxia Yang, Shuai Liu, Ziyi Xu, Liang Wang, Junli Shi, Wenkang Liu, Jian Yang, Dianwei Liu, Hang Yao, Wenyong Fei   +11 more
wiley   +1 more source