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Hemoglobin C-I-A

Acta Haematologica, 1980
Hemoglobin I (alpha 16 lys leads to glu) was identified in association with hemoglobins C and A in a black American woman who had no clinical or hematologic disease. Her erythrocytes contained four major hemoglobins, all of which were separable by DEAE-cellulose column chromatography.
George R. Honig, Marsha Borders
openaire   +2 more sources

The organization of hemoglobin in erythrocytes containing hemoglobin A or hemoglobin C

Canadian Journal of Physiology and Pharmacology, 1970
Red cells containing hemoglobin C have been shown to behave as if they are more rigid than normal cells that contain hemoglobin A. Under some conditions the former cells contain inclusions that appear to be crystalline. This study shows, by X-ray scattering and diffraction, that the inclusions are crystalline.
R. P. Rand, S. Charache
openaire   +3 more sources

Protein solvation in allosteric regulation: a water effect on hemoglobin.

Science, 1992
The oxygen affinity of hemoglobin varies linearly with the chemical potential of water in the bathing medium, as seen from the osmotic effect of several neutral solutes, namely sucrose, stachyose, and two polyethyleneglycols (molecular weights of 150 and
M. F. Colombo, D. Rau, V. Parsegian
semanticscholar   +1 more source

Homozygous hemoglobin C disease

Blood, 2013
![Figure][1] A 44-year-old African American female presented with a pain crisis and a history of hemoglobinopathy, menometrorrhagia secondary to acquired von Willebrand factor (vWF) deficiency, and a history of multiple vaso-occlusive events necessitating lifelong warfarin therapy ...
Samir Dalia, Ling Zhang
openaire   +3 more sources

Elective surgery without transfusion: influence of preoperative hemoglobin level and blood loss on mortality.

American Journal of Surgery, 1990
To clarify the widespread practice of preoperative transfusion to attain a 10 g/dL level of hemoglobin, the relationship between preoperative hemoglobin level, operative blood loss, and mortality was studied by analyzing the results of 113 operations in ...
R. Spence   +8 more
semanticscholar   +1 more source

Static and dynamic light scattering approach to the hydration of hemoglobin and its supertetramers in the presence of osmolites.

Biopolymers, 2002
We used static and dynamic light scattering for comparing the mass (MW) and hydrodynamic radius (R(h)) of several hemoglobin systems, namely human hemoglobin, bovine hemoglobin, human hemoglobin cross-linked with a sebacyl residue, and bovine hemoglobin ...
D. Arosio   +4 more
semanticscholar   +1 more source

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