Results 31 to 40 of about 19,761,729 (373)

Stability of hematological analytes during 48 hours storage at three temperatures using Cell-Dyn hematology analyzer [PDF]

open access: yesJournal of Medical Biochemistry, 2021
Background: The complete blood count (CBC) with differential leukocyte count (DLC) is one of the most common tests requested by physicians. The results of this test are affected by storage temperature and time of incubation.
Unalli Ozmen Sevda, Ozarda Yesim
doaj   +1 more source

Multispectral imaging for MicroChip electrophoresis enables point-of-care newborn hemoglobin variant screening

open access: yesHeliyon, 2022
Hemoglobin (Hb) disorders affect nearly 7% of the world’s population. Globally, around 400,000 babies are born annually with sickle cell disease (SCD), primarily in sub-Saharan Africa where morbidity and mortality rates are high.
Ran An   +14 more
doaj   +1 more source

Validation and determination of a reference interval for Canine HbA1c using an immunoturbidimetric assay [PDF]

open access: yes, 2017
Background: Hemoglobin A1c (HbA1c) provides a reliable measure of glycemic control over 2–3 months in human diabetes mellitus. In dogs, presence of HbA1c has been demonstrated, but there are no validated commercial assays. Objective: The purpose
Goemans, Anne F.   +2 more
core   +1 more source

Hematologic and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease

open access: yesHaematologica, 2013
The aim of the study was to determine the factors associated with resting and exercise-induced hemoglobin oxygen desaturation. The well-established six-minute walk test was conducted in 107 sickle cell children (50 with sickle hemoglobin C disease and 57
Xavier Waltz   +12 more
doaj   +1 more source

Intraerythrocytic Hemoglobin Crystals in Sickle Cell-Hemoglobin C Disease [PDF]

open access: yesBlood, 1965
Abstract On 70 per cent of the blood smears from 60 cases of electrophoretically proven sickle cell-hemoglobin C disease, there is observed a misshapen erythrocyte that contains condensed hemoglobin crystals which are dark-hued, homogeneous and elongated and which have parallel sides with one end terminating in a pyramid or rounded shape.
L W, DIGGS, A, BELL
openaire   +2 more sources

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

open access: yesACS Medicinal Chemistry Letters, 2017
We report the discovery of a new potent allosteric effector of sickle cell hemoglobin, GBT440 (36), that increases the affinity of hemoglobin for oxygen and consequently inhibits its polymerization when subjected to hypoxic conditions.
B. Metcalf   +23 more
semanticscholar   +1 more source

Effect of Multifactorial Treatment Targets and Relative Importance of Hemoglobin A1c, Blood Pressure, and Low‐Density Lipoprotein‐Cholesterol on Cardiovascular Diseases in Chinese Primary Care Patients With Type 2 Diabetes Mellitus: A Population‐Based Retrospective Cohort Study

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background The relative effect of hemoglobin A1c, blood pressure, and low‐density lipoprotein‐cholesterol (LDL‐C) (“ABC” factors) on the prevention of cardiovascular diseases (CVD) among patients with type 2 diabetes mellitus is poorly understood.
E. Wan   +6 more
semanticscholar   +1 more source

Altered membrane structure and surface potential in homozygous hemoglobin C erythrocytes. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Hemoglobin C differs from normal hemoglobin A by a glutamate-to-lysine substitution at position 6 of beta globin and is oxidatively unstable. Compared to homozygous AA erythrocytes, homozygous CC erythrocytes contain higher levels of membrane ...
Fuyuki Tokumasu   +6 more
doaj   +1 more source

Remark on “Establishment and Validation of the Risk Nomogram of Poor Prognosis in Patients with Severe Pulmonary Infection Complicated with Respiratory Failure” by Qiang et al [Letter]

open access: yesInternational Journal of General Medicine, 2023
Dongrui Liang,1 Xiaodong Li2 1Department of Ophthalmology, Baoding No. 1 Central Hospital of Hebei Medical Universtiy, Baoding, Hebei, People’s Republic of China; 2Department of Nephrology, Baoding No. 1 Central Hospital of Hebei Medical Universtiy,
Liang D, Li X
doaj  

Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer : randomized clinical trial [PDF]

open access: yes, 2013
BACKGROUND: The AGO-ETC trial compared 5-year relapse-free survival of intense dose-dense (IDD) sequential chemotherapy with epirubicin (E), paclitaxel (T), and cyclophosphamide (C) (IDD-ETC) every 2 weeks vs conventional scheduled epirubicin ...
Bois, Andreas du   +13 more
core   +1 more source

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