Results 71 to 80 of about 1,975,307 (342)

PATIENTS AT RISK OF THEIR ETHNIC BACKGROUND [PDF]

Romanian Journal of Pediatrics, 2009
This article discuss genetic disorders that appear with increased frequency in certain ethnic groups: – Ashkenazi jews: Tay-Sachs disease, adult Gaucher’s disease – type I, Niemann-Pick disease, mucolipidosis (type IV), pentosuria, Bloom syndrome ...
Valeriu Popescu
doaj   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

C-Reactive protein and risk of ESRD: results from the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT) [PDF]

, 2016
Background: To better understand a potential association of elevated C-reactive protein (CRP) level with progression of chronic kidney disease (CKD), we examined the relationship of CRP level with the development of end-stage renal disease (ESRD) in ...
Burdmann, Emmanuel A., Claggett, Brian, Eckardt, Kai-Uwe, Kewalramani, Reshma, Levey, Andrew S., Mc Causland, Finnian R., McMurray, John J.V., Parfrey, Patrick, Pfeffer, Marc A., Remuzzi, Giuseppe, Singh, Ajay K., Solomon, Scott D., Toto, Robert D.   +12 more
core   +1 more source

beta-thalassemia intermedia in a Brazilian patient with - 101(C > T) and codon 39 (C > T) mutations

São Paulo Medical Journal
CONTEXT: We verified molecular alterations in a 72-year-old Brazilian male patient with a clinical course of homozygous beta-thalassemia intermedia, who had undergone splenectomy and was surviving without regular blood transfusions.
Sylvia Morais de Sousa, Letícia Khater, Luís Antônio Peroni, Karine Miranda, Marcelo Jun Murai, Dulcinéia Martins Albuquerque, Paulo Arruda, Sara Terezinha Ollala Saad, Fernando Ferreira Costa   +8 more
doaj   +1 more source

Asymptomatic hemochromatosis case with HFE c.1007−47G>A, c.340+4T>C heterozygous mutations and alpha globin −3.7 kb deletion

Egyptian Journal of Medical Human Genetics, 2018
Background: Hereditary hemochromatosis is a disease associated with iron deposition which is caused by the mutations in “hereditary Fe (iron)” (HFE) gene. Case: The 16-year-old male patient was diagnosed with hereditary hemochromatosis after c.1007−47G>A
Vesile Deniz Çelik, Betul Orhan Kiliç, Yasemin Ardiçoğlu Akişin, Fatma Ajlan Tükün, Nejat Akar   +4 more
doaj   +1 more source

Changes in the Conformational State of Hemoglobin in Hemodialysed Patients with Chronic Renal Failure [PDF]

, 2015
The aim of this study was to evaluate the properties of internal components of erythrocytes in chronic renal failure (CRF) patients undergoing hemodialysis (HD) in comparison to control subjects.
Gwozdzinski, Krzysztof, Pieniążek, Anna   +1 more
core   +4 more sources

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Oxidative stress in preeclampsia and the role of free fetal hemoglobin

Frontiers in Physiology, 2015
Preeclampsia is a leading cause of pregnancy complications and affects 3–7 % of pregnant women. This review summarizes the current knowledge of a new potential etiology of the disease, with a special focus on hemoglobin-induced oxidative stress ...
Stefan Rocco Hansson, Åsa eNääv, Lena eErlandsson   +2 more
doaj   +1 more source

Studies on the Hemoglobin of Cooley's Anemia and Cooley's Trait [PDF]

, 1952
The diseases sickle cell anemia and Cooley's anemia (also known as thalassemia or Mediterranean anemia) have associated with them "minor" or "trait" forms of the disease in which the symptomatology is minimal, and the abnormalities in the red cells are ...
Rich, Alexander
core  

The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]

, 2020
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core   +1 more source