Results 51 to 60 of about 38,246 (331)

Primary prevention of hemoglobinopathies by prenatal diagnosis and selective pregnancy termination in a Muslim country: Oman

Thalassemia Reports, 2014
Hemoglobinopathies (HBP) are the most common genetic disorder in Oman and are in need of prevention programs due to the high incidence of β-thalassemia major and sickle cell disease. Prenatal diagnosis (PD) and selective pregnancy termination is shown to
Suha Mustafa Hassan, Egbert Bakker, Cornelis L. Harteveld, Piero C. Giordano   +3 more
doaj   +1 more source

Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]

, 2017
Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Ali, Bassam R., Chondrou, Vasiliki, John, Anne, Kastrinou, Vlasia, Katsila, Theodora, Kolovos, Petros, Kourakli, Alexandra, Papachatzopoulou, Adamantia, Patrinos, George P., Pavlidaki, Alexia, Sgourou, Argyro, Symeonidis, Argiris   +11 more
core   +4 more sources

Investigating the Effects of Oral Ginseng on the Cancer-Related Fatigue and Quality of Life in Patients with Non-Metastatic Cancer

International Journal of Hematology-Oncology and Stem Cell Research, 2018
Background: Cancer affects the physical, psychological, and social aspects of the patients’ life. Cancer-related fatigue (CRF) is the most common and severe condition among cancer patients. Ginseng has long been used as an efficient treatment for CRF and
Khatereh Pourmohamadi, Ahmad Ahmadzadeh, Mahmood Latifi   +2 more
doaj   +1 more source

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH). [PDF]

Int J Gynaecol Obstet
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Ubom AE, Begum F, Ramasauskaite D, Nieto-Calvache AJ, Oguttu M, Nunes I, Malel ZJ, Beyeza-Kashesya J, Wright A, FIGO Committee on Childbirth and Postpartum Hemorrhage.   +9 more
europepmc   +2 more sources

Hemoglobinopathies and Hemoglobin A1c in Diabetes Mellitus

Journal of Diabetes Science and Technology, 2020
Hemoglobinopathies are the most common genetically inherited single-gene disorders in the world. Their associated negative economic impact affects mainly poorer countries. According to the World Health Organization, about 5.2% of the world population and
D. Klonoff
semanticscholar   +1 more source

First report of novel mutation (c.790del) on SQSTM1 gene on a family with childhood onset of progressive cerebellar ataxia with vertical gaze palsy

Clinical Case Reports, 2022
SQSTM1 gene encodes a protein called p62 that acts as an autophagy receptor in the degradation of protein molecules. A homozygous deletion variant that changes the frame shift in the SQSTM1 gene named c.790 Del A .T was detected in case childhood onset ...
Hossein Jalali, Atefeh Khoshaeen, Mohammad Reza Mahdavi, Mahan Mahdavi   +3 more
doaj   +1 more source

Distribution of Hemoglobinopathy Disorders in Al-Kharj Province Based on Data from the Premarital Screening and Genetic Counseling Program [PDF]

Medicina (Kaunas)
Noura Al‐Dayan
europepmc   +3 more sources

Positive predictive value of diagnosis coding for hemolytic anemias in the Danish National Patient Register [PDF]

, 2016
PURPOSE: The nationwide public health registers in Denmark provide a unique opportunity for evaluation of disease-associated morbidity if the positive predictive values (PPVs) of the primary diagnosis are known.
Frederiksen, Henrik, Hansen, Dennis Lund, Overgaard, Ulrik Malthe, Pedersen, Lars   +3 more
core   +2 more sources

Anemia, micronutrient deficiencies, malaria, hemoglobinopathies and malnutrition in young children and non-pregnant women in Ghana: Findings from a national survey

PLoS ONE, 2020
Nationally representative data on the micronutrient status of Ghanaian women and children are very scarce. We aimed to document the current national prevalence of micronutrient deficiencies, anemia, malaria, inflammation, α-thalassemia, sickle cell ...
R. Wegmüller, Helena J Bentil, James P. Wirth, N. Petry, S. Tanumihardjo, L. Allen, T. Williams, L. Selenje, A. Mahama, E. Amoaful, M. Steiner-Asiedu, S. Adu-Afarwuah, F. Rohner   +12 more
semanticscholar   +1 more source

Fetal Hemoglobin in Sickle Hemoglobinopathies: High HbF Genotypes and Phenotypes

Journal of Clinical Medicine, 2020
Fetal hemoglobin (HbF) usually consists of 4 to 10% of total hemoglobin in adults of African descent with sickle cell anemia. Rarely, their HbF levels reach more than 30%.
M. Steinberg
semanticscholar   +1 more source