Results 1 to 10 of about 9,398 (186)

Burden and determinants of anaemia among in‐school young adolescents in Ethiopia, Sudan and Tanzania

open access: yesMaternal &Child Nutrition, EarlyView., 2023
‐ We found a substantial burden of anaemia among urban in‐school young adolescents in Ethiopia, Sudan and Tanzania. ‐ The prevalence and adjusted risk of anaemia were higher among boys compared with girls. ‐ Anaemia risk among young adolescents was associated with multiple modifiable indices, including poor diet quality, food insecurity and ...
Uttara Partap   +11 more
wiley   +1 more source

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera   +11 more
wiley   +1 more source

Prevention of RhD alloimmunization in the first trimester of pregnancy: Clinical practice guidelines of the French College of Obstetricians and Gynecologists

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract The French College of Obstetricians and Gynecologists has decided to update its clinical practices guidelines for preventing RhD alloimmunization in the first trimester of pregnancy. The quality of evidence of the literature was assessed following the GRADE methodology with questions formulated in the Patients, Intervention, Comparison ...
Paul Maurice   +4 more
wiley   +1 more source

FIGO position statement: Gamete donations

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Gamete donation has become a crucial part of Assisted Reproductive Technologies (ARTs), providing hope to individuals, including those who may have no other option for parenthood. This process comes with a wide range of ethical, medical, and legal challenges that need to be carefully addressed to protect the well‐being and rights of all ...
Laurie Henry   +20 more
wiley   +1 more source

Applying the National Genomic DNA Reference Materials to Evaluate the Performance of Nanopore Sequencing in Identifying Thalassemia Variants

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study mainly to evaluate the performance of nanopore technology in thalassemia detection by utilizing the national genomic reference materials in China. We proved that the reference materials can be used to evaluate the performance of nanopore sequencing in identifying thalassemia mutations, and it's necessary to incorporate triplicates when ...
Xingyu Wei   +7 more
wiley   +1 more source

Treatment Experience Using a Micro‐Induction Buprenorphine Protocol for Chronic Pain in Pediatric Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with sickle cell disease (SCD) experience painful vaso‐occlusive episodes that increase with age; a subset develops chronic pain (CP). CP is usually managed with acute pain management guidelines despite evidence of ineffectiveness.
Ashwin Patel   +6 more
wiley   +1 more source

Medication Utilization Among Children With Sickle Cell Disease in the United States

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Objective The medication management of children with sickle cell disease (SCD), especially since the release of the 2014 National Heart, Lung, and Blood Institute (NHLBI) SCD treatment guidelines, is not well described in the published literature.
Abiodun John Ologunowa   +5 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear   +6 more
wiley   +1 more source

Amniocentesis and Risk of Fetal Loss in Dichorionic‐Diamniotic Twin Pregnancy: A Case‐Control Study

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective There is a paucity of data regarding the risk of fetal loss due to invasive prenatal diagnosis in twins. The aim of the present study is to assess the rate of amniocentesis‐related fetal loss in uncomplicated dichorionic‐diamniotic (DCDA) twin pregnancies. Methods Retrospective observational case‐control study.
Sofia Roero   +11 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

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