Results 1 to 10 of about 11,317 (250)

Hemoglobinopathy SD presenting as Hemoglobinopathy SS

Medicina, 2017
This case report shows the interaction of hemoglobin (Hb) S with Hb D. in a child previously diagnosed with sickle cell anemia based on the Hb electrophoretic migration pattern in alkaline pH.
Sonia Maria Lissa, Sergio Luiz Bach, Juliana Spezia, Railson Henneberg, Paulo Henrique da Silva   +4 more
doaj   +3 more sources

Knowledge, Attitude, and Practice of Sickle Cell Disease Among Sickle Cell Disease Patients in Sudurpashchim Province of Nepal: A Cross‐Sectional Study [PDF]

Health Science Reports
Background Sickle cell disease (SCD) is a genetic hemoglobinopathy which is responsible for about 3.5% of deaths in
Gauri Datt Joshi, Sher Bahadur Kamar, Pradip Mishra, Hemraj Pandey, Sandesh Rimal, Yogendra Shah, Ravi Mohan Tiwari, Ananda Kumar Mandal, Ankit Kumar Singh, Shyam Prakash Dumre, Kishor Pandey, Eak Dev Khanal, Basu Dev Pandey, Bishnu Prasad Marasini, Pramod Joshi   +14 more
doaj   +2 more sources

An overview of complications associated with deferoxamine therapy in thalassemia [PDF]

Journal of Nephropharmacology, 2021
Thalassemic syndromes are the most common genetic diseases in the world that are related to blood transfusion and iron overload in the body. In ß-thalassemia major multiple blood transfusions due to ineffective erythropoiesis lead to iron excess in the ...
Bijan Keikhaei, Neda Farmani-Anooshe, Mohammad Bahadoram, Mohammad-Reza Mahmoudian-Sani, Kosar Alikhani, Ammar Helalinasab   +5 more
doaj   +1 more source

COVID-19 and Hemoglobinopathies: A Systematic Review of Clinical Presentations, Investigations, and Outcomes

Frontiers in Medicine, 2021
This systematic review aimed to provide an overview of the clinical profile and outcome of COVID-19 infection in patients with hemoglobinopathy. The rate of COVID-19 mortality and its predictors were also identified.
Jun Xin Lee, Wei Keong Chieng, Sie Chong Doris Lau, Chai Eng Tan   +3 more
doaj   +1 more source

Hemoglobinopathies [PDF]

Vnitřní lékařství, 2018
This article summarize molecular-genetic basis of hemoglobinopathies, their classification and phenotypic manifestations. The description of individual subgroups is supplemented with a case reports of patients diagnosed in the Czech population. This paper provides an overview of 14 types of α-thalassemic mutations, 34 β-thalassemic alleles, 4 δβ ...
Karel, Indrák, Martina, Divoká, Dagmar, Pospíšilová, Jaroslav, Čermák, Monika, Beličková, Monika, Horváthová, Vladimír, Divoký   +6 more
openaire   +2 more sources

A National Registry of Thalassemia in Turkey: Demographic and Disease Characteristics of Patients, Achievements, and Challenges in Prevention

Turkish Journal of Hematology, 2018
Objective: The Turkish Society of Pediatric Hematology set up a National Hemoglobinopathy Registry to demonstrate the demographic and disease characteristics of patients and assess the efficacy of a hemoglobinopathy control program (HCP) over 10 years in
Yeşim Aydınok, Yeşim Oymak, Berna Atabay, Gönül Aydoğan, Akif Yeşilipek, Selma Ünal, Yurdanur Kılınç, Banu Oflaz, Mehmet Akın, Canan Vergin, Melike Sezgin Evrim, Ümran Çalışkan, Şule Ünal, Ali Bay, Elif Kazancı, Talia İleri, Didem Atay, Türkan Patıroğlu, Selda Kahraman, Murat Söker, Mediha Akcan, Aydan Akdeniz, Mustafa Büyükavcı, Güçhan Alanoğlu, Özcan Bör, Nur Soyer, Nihal Özdemir Karadaş, Ezgi Uysalol, Meral Türker, Arzu Akçay, Süheyla Ocak, Adalet Meral Güneş, Hüseyin Tokgöz, Elif Ünal, Naci Tiftik, Zeynep Karakaş   +35 more
doaj   +1 more source

Ferritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study

Scientific Reports, 2022
Ferritin is frequently used to screen some dire consequences of iron overload in β-thalassemia patients. The study aimed to define the best cutoff point of ferritin to screen for cardiac and liver hemosiderosis in these cases.
Hadi Darvishi-Khezri, Aily Aliasgharian, Mohammad Naderisorki, Mehrnoush Kosaryan, Mobin Ghazaiean, Hanie Fallah, Mohammad Zahedi, Hossein Karami   +7 more
doaj   +1 more source

Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]

, 2017
Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Ali, Bassam R., Chondrou, Vasiliki, John, Anne, Kastrinou, Vlasia, Katsila, Theodora, Kolovos, Petros, Kourakli, Alexandra, Papachatzopoulou, Adamantia, Patrinos, George P., Pavlidaki, Alexia, Sgourou, Argyro, Symeonidis, Argiris   +11 more
core   +5 more sources

Time to Do Something for Vitamin D Deficiency; A Review

Journal of Pediatrics Review, 2015
Context: Vitamin D deficiency is a common nutritional disorder in Iran. Vitamin D is an essential health factor from birth onward. This study was conducted to summarize epidemiologic researches regarding vitamin D deficiency in different parts of the ...
Mehrnoush Kosaryan, Mandana Zafari , Aili Aliasgharian, Masomeh Mosawi   +3 more
doaj   +3 more sources

Early Screening of Hemoglobinopathy in Indonesia Using Erythrocyte Indices

Indonesian Biomedical Journal, 2017
BACKGROUND: The mutation spectrums of hemoglobinopathy are different among populations that yield a different result of erythrocyte indices. Calculation of erythrocyte indices with some formula has been reported to differentiate between hemoglobinopathy ...
Yenny Surjawan, Hwee Lian Tan, Rahajuningsih Dharma Setiabudy, Wiwik Rositawati   +3 more
doaj   +1 more source