Results 101 to 110 of about 24,308 (321)

Hemoglobin E Hemoglobinopathy in an Adult from Assam with Unusual Presentation: A Diagnostic Dilemma

Journal of Laboratory Physicians, 2016
Hemoglobin E (HbE) is estimated to affect at least one million people around the world. Carrier frequency of hemoglobin E/β-thalassemia (HbE/β-thalassemia) is highest in Southeast Asia, reaching as high as 60% in parts of Thailand, Laos, and Cambodia. In
S. S. Kiran, Saraswathy Aithal, C. S. Belagavi   +2 more
semanticscholar   +1 more source

Tocilizumab provides a potential therapeutic option for the management of hyperhaemolysis syndrome in sickle cell disease: A case series and brief narrative overview of the literature

Transfusion Medicine, EarlyView.
Abstract Background and Objectives Hyperhaemolysis syndrome is a life‐threatening complication of transfusion, potentially triggered by macrophage activation, with limited treatment options. Tocilizumab, an anti‐IL6 monoclonal antibody, has mechanistic rationale for use and has been shown to be effective in a small number of cases.
S. Wolf, B. Singh, A. Zaidi, P. Greaves, F. Oyesanya, S. Bennett, B. Kaya, F. Barroso, P. Telfer   +8 more
wiley   +1 more source

Characterisation of RHD and RHCE variations in blood donors from Jazan Province, Southwestern Saudi Arabia

Transfusion Medicine, EarlyView.
Abstract Background and Objectives Rh is among the most important and highly polymorphic blood group systems due to the proximity of the RHD and RHCE genes, which encode numerous highly immunogenic antigens. However, in areas of Saudi Arabia with a high prevalence of hemoglobinopathy, the molecular characteristics of RHD and RHCE variations are lacking.
Maymoon M. Madkhali, Mayisah Khormy, Abdullah A. Meshi, Bandar Kameli, Khaled Ghazwani, Ohoud Sufyani, Salha Hakami, Yahya Khawaji, Abdullah A. Mobarki, Khaled Essawi, Waleed Hakami, Yara Alyahyawi, Aymen M. Madkhali, Gasim Dobie, Hassan A. Hamali   +14 more
wiley   +1 more source

جداسازی زنجيره‌های گلوبين به روش کروماتوگرافی تعويض يونی در تشخيص هموگلوبينوپاتی‌ها [PDF]

, 2008
زمينه و هدف: هموگلوبينوپاتی‌ها در اثر نقص در ژن سنتز کننده زنجيره‌های هموگلوبين بوجود می‌آيند. در مواقعی که موتاسيون در ژن زنجيره‌های آلفا يا بتا بصورتی باشد که تغيير بار الکتريکی هموگلوبين محسوس نباشد، برای تفکيک می‌توان از کروماتوگرافی تعويض يونی بهره ...
حسينی گوهری, لادن, شمسيان, بی بی شهین, مستعان, لیلا, معينی عليشاه, فاطمه   +3 more
core  

RhD‐negative red blood cell use and conservation strategies in the Region of Southern Denmark

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Suboptimal use of RhD‐negative red blood cells (RBCs) can lead to reduced inventories of this scarce resource. Prevention of D‐alloimmunization is particularly important for RhD‐negative females of childbearing potential (FCPs).
Emil Ainsworth Jochumsen, Kjell E. Titlestad, Ulrik Sprogøe, Mark H. Yazer   +3 more
wiley   +1 more source

Radiological findings of Posterior Reversible Encephalopathy Syndrome in transplanted children previous affected by hemoglobinopathy: A neuroimaging retrospective analysis

European Journal of Radiology Open, 2019
To evaluate, by Magnetic Resonance Imaging, if there is a typical pattern or severity of PRES in transplanted children for hemoglobinopathy. Secondary point was to investigate the pattern and severity of PRES in children with thalassemia-THAL and sickle ...
Eliseo Picchi, Francesca Di Giuliano, Simone Marziali, Silvia Minosse, Valentina Ferrazzoli, Valerio Da Ros, Javid Gaziev, Chiara Adriana Pistolese, Roberto Floris, Francesco Garaci   +9 more
doaj   +1 more source

Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions [PDF]

, 2016
Babesia microti, a tick-transmitted, intraerythrocytic protozoan parasite circulating mainly among small mammals, is the primary cause of human babesiosis.
Ben Mamoun, Choukri, Brancato, Jana, Chibucos, Marcus, Colinge, Jacques, Cornillot, Emmanuel, Crabtree, Jonathan, Dwivedi, Ankit, Fraser, Claire M., Frutos, Roger, Gotia, Hanzel T., Hung, Chris, Ifeonu, Olukemi O., Krause, Peter J., Kumar, Vidya, Kumari, Priti, Lawres, Lauren, McCracken, Carrie, Molina, Douglas M., Orvis, Joshua, Ott, Sandy, Pablo, Jozelyn V., Pazzi, Joseph E., Reynes, Christelle, Sadzewicz, Lisa, Sengamalay, Naomi, Shetty, Amol C., Silva, Joana C., Su, Qi, Tallon, Luke, Tretina, Kyle, Usmani-Brown, Sahar, Virji, Azan Z.   +31 more
core   +3 more sources

Distribution of hemoglobinopathy phenotypes in western Kenya: a retrospective study done at Aga Khan Hospital, Kisumu [PDF]

, 2022
Benard Mutua, George Sowayi, Patrick Okoth   +2 more
openalex   +1 more source

Exploring low haemoglobin density as a no‐added‐cost screening marker to assess iron deficiency

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Iron deficiency (ID), with or without anaemia, affects over 1 billion people globally. Early detection is essential, but current diagnostic tools may be costly, logistically complex and not widely accessible. This study evaluates low haemoglobin density percentage (LHD%), derived from mean corpuscular haemoglobin ...
Jesse Qiao, Sherif Rezk, Gagan Mathur
wiley   +1 more source

A Novel Association of HbQ India Trait with Sickle Cell Anemia: a New Insight in Hemoglobinopathies [PDF]

, 2022
Rakesh Kumar Gupta, Kartavya Kumar Verma, Gurmeet Singh   +2 more
openalex   +1 more source