Results 111 to 120 of about 24,308 (321)

Cost‐effectiveness of a hypothetical assay to evaluate stored blood quality prior to transfusion

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Unsuccessful red blood cell (RBC) transfusion, necessitating unscheduled repeat transfusion, is common and costly. Several technologies have been developed to assess stored blood quality, but the potential cost‐effectiveness of pretransfusion testing versus no testing to prevent unscheduled re‐transfusion is unknown ...
Melissa C. Caughey   +3 more
wiley   +1 more source

Combination iron chelation therapy with deferiprone and deferasirox in iron-overloaded patients with transfusiondependent β-thalassemia major

open access: yesClinics and Practice, 2017
There are few papers on the combination therapy of deferiprone (DFP) and deferasirox (DFX) in iron-overloaded patients with transfusion-dependent β-thalassemia major (β-TM). A total of 6 patients with β-TM (5 males and 1 female) with a mean age of 23.8±5.
Hossein Karami   +4 more
doaj   +1 more source

Clinical and haematological features of hyperhaemolysis in sickle cell disease: A case series from two tertiary care centres

open access: yes
British Journal of Haematology, EarlyView.
Jaehyup Kim   +8 more
wiley   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida   +4 more
wiley   +1 more source

Importance and Potential of Rare Disease Research in Pediatric Rheumatology and Beyond: Pushing Frontiers

open access: yesACR Open Rheumatology, Volume 7, Issue 12, December 2025.
Although individually occurring in less than 1 in 2,000 people, cumulatively, more than 7,000 rare diseases affect approximately 6% of the population worldwide. Children and young people are disproportionally challenged in number and severity, which may be explained by the large proportion of genetic conditions among rare diseases (70%–80%). Indeed, an
Christian M. Hedrich
wiley   +1 more source

Asymtomatic essential thrombocythemia in a child: a rare case report

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2013
Essential thrombocythemia is a rare myeloproliferative disorder in pediatrics. This myeloproliferative disorder is charactherized by thrombocytosis and hyperplasia of megakaryocytes in the bone marrow. Other cell lines are not involved.JAK2V617Fmutations
Majid Vafaie   +4 more
doaj  

Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]

open access: yes, 2012
Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard
core  

A Small Key for a Heavy Door: Genetic Therapies for the Treatment of Hemoglobinopathies [PDF]

open access: gold, 2021
Hidde A. Zittersteijn   +6 more
openalex   +1 more source

Red blood cell parameters in antenatal nonsickling hemoglobinopathy screening

open access: yesInternational Journal of Women's Health, 2015
Objective To find a hematological parameter and the cut-off level for identification of nonsickling hemoglobinopathies in pregnant women. Materials and methods Venous blood samples of 849 women with singleton pregnancies were collected at the first visit.
G. Bencaiova   +3 more
semanticscholar   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, Volume 6, Issue 12, December 2025.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

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