Results 31 to 40 of about 9,398 (186)

Prevention of the Hemoglobinopathies

Thalassemia Reports, 2013
The inherited hemoglobin disorders not only cause suffering and unhappiness to the patients but they also absorb a large part of resources and human effort in several countries which harbor the deleterious genes [...]
openaire   +4 more sources

Improving Communication between Doctors and Parents after Newborn Screening [PDF]

, 2011
Background: Newborn screening (NBS) enables early treatment, and some consider it a natural vehicle for genetic screening. Bioethicists argue for caution since families of infants with carrier status can develop psychosocial complications.
Christopher, Stephanie, Collins, Jenelle, Eskra, Kerry, Farrell, Michael, Farrell, Philip M., Hoffman, Gary, Kennedy-Parker, Karen, La Pean, Alison, Panepinto, Julie, Tluczek, Audrey   +9 more
core   +2 more sources

Hemoglobinopathies in the Fetal Position [PDF]

Obstetric Anesthesia Digest, 2018
(N Engl J Med. 2018;379:1675–1677) Hemoglobinopathies are disorders caused by mutations in genes that encode globins and include sickle cell disease and β-thalassemia. It has been reported that adults with these hemoglobinopathies who have comparatively high levels of fetal hemoglobin (HbF) have better clinical outcomes than those with low ...
Pasricha, S, Drakesmith, H
openaire   +5 more sources

Provision of peri‐operative patient blood management strategies in the UK: a national survey of practice

Anaesthesia, EarlyView.
Summary Introduction In UK hospitals, it is unclear how organisational structures are arranged to support effective implementation of peri‐operative blood management practice strategies. The aim of this study was to conduct a national survey of organisations to describe local practices of peri‐operative patient blood management and infrastructure ...
Samantha R. Warnakulasuriya, Kathleen Wolff, Simon J. Stanworth, on behalf of the Research and Audit Federation of Trainees group and the NIHR BTRU in Data Driven Transfusion Practice Collaborators, Hayley Evans, Alwyn Kotze, Mike Murphy, Antony Palmer, Akshay Shah, Noemie Roy, Martha Belete, William Spencer, Katie Preston, Rebecca Hawes, Reeanne Jones, Murray Williams, Ahmed Ibrahim, Aimi Lara Emilie Jeanes, Akshay Shah, Alan Race, Alexander Bell, Alison Chalmers, Alison Evans, Amarjeet Patil, Amelia Van Manen, Amy Thomas, Anandh Balu, Annette Haines, Annie Smith, Apurva Patil, Ashish Gandhi, Ashley McIlroy, Asya Veloso Costa, Barrie Philip Robertson, Beatrice Meilak, Ben Chandler, Bhavesh Gohil, Carlos Eduardo Abrunhosa de Mattos, Charlotte Katie Morris, Chintan Vora, Chiu Lee, Chris Oscier, Christopher Dixon, Ciara O'Brien, Clare Dallimore, Clare Quaterman, Colette Keenan, Cristian Lasai, Dale Seddon, Daniel Haslam, Darren Caldow, David Perry, Declan Love, Dina Bowey, Earlene Armstrong, Elizabeth Ribey, Emily Yeung, Emma Jacobs, Farzana Begum, Freya Brownlow, Gautam Dhananjay Modak, Gemma Talling, Georgia Monantera, Gomathy Kandasamy, Hannah Houston, Hannah Kennedy, Hannah Louise Headon, Helen Tyler, Henry Sergeant, Ismaa Aslam, Jade Loughran, Jake Melhuish, James Kirkland, James Morris, Jane Doherty, Jennifer Brooke, Jennifer Phillips, Jessica Irwin, Joel Prescott, Jordan McVey, Josephine Barnsley, Ka Po Tam, Katherine Saunders, Kim Rhodes, Krupa Basavaraj, Kush Amin, Laura Carter, Laura Field, Laura Fulton, Laura Scott, Leon Cohen, Louis Murphy, Madeleine Edwards, Madhavi Gudipati, Magde Albarade, Mai Wakatsuki, Manaf Al‐Bayati, Mark Dorrance, Marta Malaj, Matt Bridge, Matthew Peacock, Maya Sussman, Michael Jarvis, Michael Olivier, Mohamed Elbahnasy, Mohammad Sharif, Molly Janowski, Nadeeshya Dulanjalee Welikala, Naomi R C Adey, Nicola Coverdale, Noorunisa Suhail, Oliver Dare, Orlagh McNally, Paul Young, Pei Shan Lim, Peter Sandbach, Philippa Horne, Prathiban Kumar, Puja Chhaniyara, Putri Rimba, Rabia Ghani, Rashmi Rebello, Rebecca Allott, Rebecca Vickers, Richard Timoney, Rishi Naik, Robert Davidson, Robert Palin, Rosanna Seatter, Rotimi Latinwo, Ruchi Maniar, Ryad Sammy Chebbout, Sabba Aziz, Samah Alimam, Samuel Lichfield, Sharon Ramirez, Shashiharen Gnanapandithen, Shashikant Yegnaram, Shriyam Patel, Simon Beecroft, Sioned Elin Davies, Stephanie Worrall, Stuart Cleland, Subhadra Devi Balakrishnan, Suji Pararajasingam, Sumithre Gunathilake, Svetlana Kulikouskaya, Tajwinder Singh Sandhar, Tina Vaz, Toby Reynolds, Tom Kingston, Val Luoma, William Booth, Xiaosu Jiang, Zaid Saghir Ahmed, Zwesty Viera   +155 more
wiley   +1 more source

Gene Therapy for Hemoglobinopathies [PDF]

Human Gene Therapy, 2018
Gene therapy for β-thalassemia and sickle-cell disease is based on transplantation of genetically corrected, autologous hematopoietic stem cells. Preclinical and clinical studies have shown the safety and efficacy of this therapeutic approach, currently based on lentiviral vectors to transfer a β-globin gene under the transcriptional control of ...
Cavazzana M., Mavilio F.
openaire   +3 more sources

A systematic review on the determinants of long‐term kidney sequelae after hypertensive diseases of pregnancy

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This systematic review aimed to evaluate the risk of chronic kidney disease (CKD) after preeclampsia and the determinants of these sequelae. Five authors found a more significant risk of kidney disease after PE, with a risk ranging from two to three times higher.
Marie Haudiquet, Marion D'Incau, Vincent Letouzey, Olivier Moranne   +3 more
wiley   +1 more source

Exertional sickling: Questions and controversy [PDF]

, 2014
Sickle cell trait (SCT) occurs in about 8% of African-Americans and is often described to be of little clinical consequence. Over time, a number of risks have emerged, and among these are rare but catastrophic episodes of sudden death in athletes and ...
Blinder, Morey A., Russel, Sarah
core   +3 more sources

Effect of Maternity Units' Organizational Levels on Maternal Birth Satisfaction: A Multicentric Cohort Study

Birth, EarlyView.
ABSTRACT Introduction Maternal birth satisfaction is correlated to long‐term outcomes and is influenced by the place of birth. In Italy, most births occur in hospitals. Our study aimed to assess whether the organizational level (I vs. II) of the Maternity Unit (MU) had any impact on birth satisfaction.
Simona Fumagalli, Antonella Nespoli, Maria Panzeri, Laura Antolini, Elisabetta Colciago, Anna Adami, Matilde Maria Canepa, Elsa Del Bo, Raffaella Ferrara, Paola Agnese Mauri, Angelo Cagnacci, Marcello Ceccaroni, Carmen Dattolo, Giovanna Esposito, Massimo Piergiuseppe Franchi, Franco Gorlero, Gianpaolo Grisolia, Francesca Grosso, Agnese Lecis, Marta Mazzeo Melchionda, Virginia Michelerio, Luana Mogavino, Chiara Ogliari, Michela Ramunno, Arsenio Spinillo, Sabrina Valletta, Patrizia Vergani, Anna Locatelli   +27 more
wiley   +1 more source

Maternal and perinatal outcomes of sickle cell disease in pregnancy: A nationwide study in France

British Journal of Haematology, Volume 206, Issue 4, Page 1218-1227, April 2025.
Summary This nationwide cohort study provides a comprehensive overview of maternal and perinatal outcomes associated with sickle cell disease (SCD) during pregnancy. Using the French national health database, all singleton pregnancy‐related hospital discharges from 2013 to 2020 in women aged 15–55 (n = 5 752 080) were selected.
Alice Corsia, Laure Joseph, Nathanael Beeker, Sandra Manceau, Marine Driessen, Benoit Meunier, Marina Cavazzana, Mathis Collier, Jean‐Marc Treluyer   +8 more
wiley   +1 more source

Genetic Disease Burden, Nutrition and Determinants of Tribal Health Care in Chhattisgarh State of Central-East India: A Status Paper [PDF]

, 2011
Tribal health is an important aspect of development and progress of the people. This study pertaining to genetic disease burden, nutritional status and biomedical anthropological assessment with particular reference to determinants of tribal health care ...
Balgir, RS
core   +1 more source