Results 71 to 80 of about 9,800 (200)

Epidemiological and Clinical Profile of Hemoglobinopathies and Thalassemia in Duhok, Kurdistan Region of Iraq: A Retrospective Study

Thalassemia Reports
Background/Objectives: Thalassemia is among the most common hereditary disorders globally, characterized by impaired hemoglobin synthesis and ineffective erythropoiesis.
Burhan Abdullah Zaman, Zuhair Rushdi Mustafa, Delshad Abdulah Mohamed, Hasan Abdullah Aswad, Deldar Morad Abdulah   +4 more
doaj   +1 more source

TNFAIP3 Gene Polymorphisms and the Risk of Thrombocytopenia: A Cross‐Sectional Study in Iranian Population

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction Thrombocytopenia, particularly immune thrombocytopenic purpura, is a prevalent hematological disorder characterized by low platelet counts, leading to increased bleeding risks. Genetic factors, including single nucleotide polymorphisms, are implicated in its pathogenesis.
Sorour Alizadeh Saadooni, Zeinab Eftekhar, Mohammad Ali Jalali Far, Najmaldin Saki, Gholam Abbas Kydani, Hossein Karimpourian, Ali Aminasnafi   +6 more
wiley   +1 more source

Vitamin D and its receptor polymorphisms: New possible prognostic biomarkers in leukemias

Oncology Reviews, 2018
Several factors such as chromosomal translocations, gene mutations, and polymorphisms are involved in the pathogenesis of leukemia/lymphoma. Recently, the role of vitamin D (VD) and vitamin D receptor (VDR) polymorphisms in hematologic malignancies has ...
Seyed Mohammad Sadegh Pezeshki, Ali Amin Asnafi, Abbas Khosravi, Mohammad Shahjahani, Shirin Azizidoost, Saeid Shahrabi   +5 more
doaj   +1 more source

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies [PDF]

, 2022
Vigneshwaran Venkatesan, Abisha Crystal Christopher, Prathibha Babu, Manoj Kumar K. Azhagiri, Kaivalya Walavalkar, Bharath Saravanan, Saranya Srinivasan, Karthik V. Karuppusamy, Annlin Jacob, Sumathi Rangaraj, Abhirup Bagchi, Aswin Anand Pai, Yukio Nakamura, Poonkuzhali Balasubramanian, Rekha Pai, Srujan Marepally, Kumarasamypet M. Mohankumar, Shaji R Velayudhan, Dimple Notani, Alok Srivastava, Saravanabhavan Thangavel   +20 more
openalex   +1 more source

Association of IL28B Polymorphisms With Hepatitis C Susceptibility in Southern Iran's β‐Thalassemia Population: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Thalassemia is a hereditary hematological condition which interferes with the production of hemoglobin (Hb). Patients with thalassemia require regular blood transfusion, which makes them highly susceptible to pathogens, and especially viral pathogens.
Fatemeh Askari, Masoud Kargar, Zeinab Deris Zayeri, Mohammad Ali Jalalifar, Bijan Keikhaei, Gholam Abbas Kaydani   +5 more
wiley   +1 more source

Prevalence and Mortality Outcomes of Melioidosis in Thalassemia: A Systematic Review and Meta-Analysis

Medical Sciences
Background. Melioidosis is a severe infection caused by Burkholderia pseudomallei and is endemic in regions with a high prevalence of thalassemia. Patients with thalassemia are thought to be at increased risk due to iron overload, splenectomy, and immune
Jongkonnee Thanasai, Kritsada Singha, Atthaphong Phongphithakchai, Moragot Chatatikun, Sa-ngob Laklaeng, Jitabanjong Tangpong, Pakpoom Wongyikul, Phichayut Phinyo, Supphachoke Khemla, Anchalee Chittamma, Wiyada Kwanhian Klangbud   +10 more
doaj   +1 more source

Splenic sequestration crisis as an index manifestation of heterozygous hemoglobinopathy in an adult [PDF]

, 2019
Eseosa Edo-Osagie, Ikponmwosa Enofe, Hisham Hakeem, P Manoj, Emmanuel A. Adomako, Mikhail Tismenetsky, Maxwell Janosky   +6 more
openalex   +1 more source

A Small Key for a Heavy Door: Genetic Therapies for the Treatment of Hemoglobinopathies [PDF]

, 2021
Hidde A. Zittersteijn, Cornelis L. Harteveld, Stefanie Klaver-Flores, Arjan C. Lankester, Rob C. Hoeben, Frank J. T. Staal, Manuel A.F.V. Gonçalves   +6 more
openalex   +1 more source

Triage and care for women with symptoms or diagnosis of pregnancy loss between 14 + 0 and 21 + 6 weeks' gestation

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 25-50, January 2026.
Abstract Mid‐trimester pregnancy loss (MTL), defined as a pregnancy loss occurring between 14 + 0 and 21 + 6 weeks of gestation, causes significant physical and emotional distress to women and presents clinical challenges to healthcare professionals. It is acknowledged that in low‐resource settings, this guideline might be applicable to births up to 28 
Caroline E. Fox, Rosinder Kaur, Kugajeevan Vigneswaran, Rachel Small, Jenny Carter, Keelin O'Donoghue, Alexander E. P. Heazell, Anna L. David, Nigel Simpson, Angharad Care, Lisa Starrs, Andrew Shennan, Catalina María Valencia González, Priya Soma‐Pillay, Leah Fitzsimmons, Adam J. Devall, Arri Coomarasamy, Mid‐trimester Pregnancy Loss Guideline Consensus Panel, Owen Arthurs, Ruth Bender‐Atik, Phil Bennett, Kirstien Boelaert, Elizabeth Bonney, Leanna Brace, Naomi Carlisle, Davide Casagrandi, Manju Chandiramani, Carolyn Chiswick, Alexandra Emms, Stella Fielder, James Goadsby, Laura Goodfellow, Jim Gray, Jemma Johns, Emma Kirk, Will Lester, Sophie Mackay, Maria Memtsa, Katie Morris, Sunbal Mukhtar, Naimah Raza, Rita Sarquis, Neil Sebire, Lucy Smith, Lucy Spencer, Amos Tetteh, Natalie Woodhead   +46 more
wiley   +1 more source

Complex karyotype in myelodysplastic syndromes: Diagnostic procedure and prognostic susceptibility

Oncology Reviews, 2019
Complex karyotype (CK) is a poor prognosis factor in hematological malignancies. Studies have shown that the presence of CK in myelodysplastic syndrome (MDS) can be associated with MDS progression to acute myeloid leukemia. The goal of this review was to
Mohammad Shahjahani, Elham Homaei Hadad, Shirin Azizidoost, Kowsar Chenani Nezhad, Saeid Shahrabi   +4 more
doaj   +1 more source