Results 71 to 80 of about 8,109 (242)

Project Sickle Cure: A Prospective, International Observational Study of Hematopoietic Cell Transplantation for Sickle Cell Disease

European Journal of Haematology, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher, Allistair Abraham, Staci D. Arnold, Christine Camacho‐Bydume, Jenny Duong, Scott Gillespie, Ann Haight, Monica L. Hulbert, Naresh Kumar, Katie Liu, Cherry Mammen, Aleksandra Mineyko, Abra Morgan, Alexander Ngwube, Robert S. Nickel, Araby Roberts, Fiona Schulte, Stephen Sands, Akshay Sharma, John T. Horan, Elizabeth O. Stenger   +20 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil, Polyxeni Delaporta, Konstantinos Bistas, Antonis Kattamis   +3 more
wiley   +1 more source

Spectrum of Thalassemia and Hemoglobinopathy Using Capillary Zone Electrophoresis: A Facility-Based Single Centred Study at icddr,b in Bangladesh

, 2023
Background: Although the global thalassemia zone covers Bangladesh, there are very limited studies conducted in this region. Therefore, the focus of our study is to understand the prevalence and burden of thalassemia and hemoglobinopathy in Bangladesh ...
Kazi Afrin Binta Hasan, Md. Zahidul Islam, Jigishu Ahmed, Palash Kanti Dhar, Anamul Hasan, Sharmine Zaman Urmee, Bikash Chandra Chanda, Raisa Akther, Abdur Rouf Siddique, Maisha Aniqua, Dinesh Mondal   +10 more
core   +1 more source

The emerging role of non-coding RNAs in the pathogenesis of infantile hemangioma

Cancer Cell International
Infantile hemangioma (IH) is a common benign tumor that occurs in children, affecting both blood vessels and soft tissues. Its pathological features include abnormal proliferation of endothelial cells and an irregular vascular structure.
Najmaldin Saki, Narjes Sadat Sadati, Zeinab Deris Zayeri, Masoud Kargar   +3 more
doaj   +1 more source

Factors Related to Reduced Bone Density in β-Thalassemia Major Patients: Mazandaran Thalassemia Registry [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: OsteoPenia and osteoPorosis are known to be one of the main comPlications of β-thalassemia major (β-TM). The aim of this study was to determine the factors associated with decreased bone density of these Patients.
Hossein Karami, Mehrnoush Kosaryan, Mohammad Naderisorki, Fatemeh esfandiari, Mobin Ghazaiean, Aily Aliasgharian, Hanie Fallah, Salameh Shakeri, Hadi Darvishi-Khezri   +8 more
doaj  

Abnormally Low Hemoglobin A1c as Harbinger of Hemoglobinopathy

, 2019
Hemoglobin A1c is frequently used in primary care to screen for and monitor disorders of glucose metabolism. A number of clinical syndromes may impact the accuracy of this laboratory value.
St. Louis, Joshua, Valdini, Anthony
core   +1 more source

Evaluation of immunophenotypic markers and clinico-hematological profile in chronic lymphocytic leukemia: implications for prognosis

BMC Research Notes, 2020
Objective Chronic lymphocytic leukemia (CLL) is an adult leukemia presented with clonal accumulation of lymphocytes. Immunophenotypic changes can be effective in predicting clinical course, the survival of patients, and determining first-line treatment ...
Marziye Bagheri, Tina Vosoughi, Mehran Hosseinzadeh, Najmaldin Saki   +3 more
doaj   +1 more source

The association between inflammatory markers in routine blood counts at 1 year and attention‐deficit/hyperactivity disorder (ADHD): A case–control study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Attention‐deficit/hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder marked by persistent patterns of inattention, disorganization, hyperactivity, and impulsivity. Increasing evidence implicates immune‐inflammatory processes in its etiology, with observed associations between ADHD and infectious diseases, allergic ...
Eugene Merzon, Ariel Israel, Shelly Salminis‐Linzen, Eli Magen, Akim Geishin, Shlomo Vinker, Ilan Green, Avivit Golan‐Cohen, Shai Ashkenazi, Stephen V. Faraone, Abraham Weizman, Iris Manor   +11 more
wiley   +1 more source

Livedoid vasculopathy in hemoglobinopathy-associated chronic leg ulcers

Chronic leg ulceration is a debilitating manifestation of hemoglobinopathies, and best management is uncertain. Livedoid vasculopathy (LV) is a cutaneous non-inflammatory thrombotic vasculopathy treated with anticoagulation that has been identified in ...
Eswaran, Harish, Moll, Stephan, Wilson, Samuel, Little, Jane   +3 more
core   +1 more source

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

Journal of Diabetes Investigation, EarlyView.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei, Michele Baldari, Lorenzo Brognara, Enrico Saudelli, Simona Moscatiello, Sara Flamigni, Francesco Traina, Alexandro Paccapelo, Uberto Pagotto, Guido Di Dalmazi   +9 more
wiley   +1 more source