Results 91 to 100 of about 1,783,252 (315)

Is Hemoglobin Variant Analysis Helpful in the Diagnostic Work-up of Patients Revealing Microcytic Erythrocytosis on Complete Blood Count? [PDF]

, 2015
Introduction: Microcytic erythrocytosis is an abnormal CBC (complete blood count) finding that is under-recognized, poorly understood, and consequently under-utilized in patient care. It is characterized by decreased MCV and increased RBC count.
Dulau-Florea, Alina, Gong, MD, Jerald Z., Gulati, Ph.D, Gene, Joneja, MD, Upasana   +3 more
core   +1 more source

Korelasi antara Gula Darah 2 Jam Postprandial Danhba1c di Laboratorium Klinik Graha Spesialis RSMH Palembang [PDF]

, 2014
Pemeriksaan gula darah merupakan pemeriksaan yang dilakukan untuk menegakkan diagnosis diabetes melitus. Hasil pemeriksaan gula darah pasien tidak cukup menggambarkan kondisi gula darah pasien, sehingga diperlukan pemeriksaan lain dengan menilai kadar ...
Habib, M. (Moh), Partan, R. U. (Radiyati), R, K. Y. (Kemas)   +2 more
core   +2 more sources

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Hemoglobin variants with electrophoretic mobility similar to hemoglobin S [PDF]

, 2017
9ª Reunião Científica da Sociedade Portuguesa de Medicina Laboratorial, 7-8 abril 2017Hemoglobinopathies are among the most common inherited diseases around the world and are one of the world’s major health problems.
Copeto, Sandra, Costa, Alcina, Costa, Sandra, Faustino, Paula, Gonçalves, João, Loureiro, Pedro, Miranda, Armandina, Seixas, Maria Teresa, Seuanes, Filomena   +8 more
core  

A Multicenter Validation of a Fully Automated Chemiluminescence Immunoassay for Plasma Elafin in Psoriasis Diagnosis and Severity Assessment

Advanced Science, EarlyView.
The fully automated CLIA demonstrates high sensitivity and specificity for plasma Elafin, achieving 88% diagnostic accuracy and an AUC of 0.92 for psoriasis detection in a multicenter cohort. The assay reliably distinguishes psoriasis from other dermatoses, objectively stratifies disease severity, and allows longitudinal monitoring, supporting its ...
Jingkun Yi, Meng Xu, Ling Han, Zhining Dong, Ruimin Liu, Xiaomei Zhang, Di Hu, Chuanjian Lu, Xiaobo Yu   +8 more
wiley   +1 more source

Spin Label Studies of the Hemoglobin–Membrane Interaction During Sickle Hemoglobin Polymerization [PDF]

, 2010
An enhanced hemoglobin–membrane association has been previously documented in sickle cell anemia. However, it is not known how this interaction is modified during the hemoglobin S polymerization process.
Falcón Dieguez, Jose, Gennaro, Ana Maria, Lores Guevara, Manuel, Rodi, Pablo Marcelo   +3 more
core   +1 more source

Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing

Advanced Science, EarlyView.
This article presents the first mechanistic model for continuous lyophilization (aka freeze drying). The model accurately describes the key phenomena and critical process parameters in continuous lyophilization, which can be used for process design, optimization, and control. Results from this work can drive the transition of (bio)pharmaceutical freeze
Prakitr Srisuma, Gang Chen, Richard D. Braatz   +2 more
wiley   +1 more source

Hemoglobin Himeji and inconsistent hemoglobin A1c values: a case report

Journal of Medical Case Reports, 2017
Background Hemoglobin A1c is used to evaluate the glycemic control in patients with diabetes and is a risk marker for chronic complications of diabetes. Hemoglobin variants are reported to falsely lower or increase hemoglobin A1c test results. We present
Vânia Guedes, Rita Bettencourt-Silva, Joana Queirós, Maria da Luz Esteves, Maria José Teles, Davide Carvalho   +5 more
doaj   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

Advanced Science, EarlyView.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +5 more
wiley   +1 more source