Results 101 to 110 of about 1,783,252 (315)
Advanced Science, EarlyView.This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao +13 more
wiley +1 more source
Advanced Science, EarlyView.Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi +10 more
wiley +1 more source
Importance of DNA Sequencing for Abnormal Hemoglobins Detected by HPLC Screening
Turkish Journal of Hematology, 2020 Duran Canatan +4 more
doaj +1 more source
Advanced Science, EarlyView.For insufficient medical emergency monitoring, this study develops a wearable system with flexible thermoelectric textiles and thermoelectric‐optical sensing. It establishes a dynamic airflow‐thermoelectric response theory (enabling 98% speech recognition) and a multi‐source fusion model for 98% emergency state recognition, aiding clinical decision ...
Zheng Zhu +10 more
wiley +1 more source
Revista Brasileira de Hematologia e Hemoterapia, 2013 OBJECTIVE: To characterize alpha-chain variant hemoglobins with electric mobility similar to that of hemoglobin S in a newborn screening program. METHODS: βS allele and alpha-thalassemia deletions were investigated in 14 children who had undefined ...
Marcilene Rezende Silva +4 more
doaj
GSK3β‐Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy
Advanced Science, EarlyView.Uterine Gsk3b knockout impairs decidual cell terminal differentiation by causing lipid droplet accumulation. GSK3β phosphorylates RNF213 to promote its lysosomal degradation, thereby enhancing lipolysis. The released fatty acids undergo β‐oxidation to generate acetyl‐CoA, which modulates histone acetylation and regulates decidual cell terminal ...
Peiran Wang +14 more
wiley +1 more source
Abnormal hemoglobins in a quarter million people
Blood, 1976 R. Schneider +7 more
semanticscholar +2 more sources
Atlas of protein sequence and structure [PDF]
Atlas of protein sequence and ...
Chang, M. A. +3 more
core +1 more source
Glycosylated Hemoglobin: The Importance in Management of Type 2 Diabetes [PDF]
, 2011 Type 2 diabetes is a major public health problem with high and increasing prevalence, morbidity and mortality. The association between diabetes and microvascular and macrovascular complications is well known besides, tight glycemic control is a necessity.
Abbas Yavari
core
Advanced Science, EarlyView.Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li +17 more
wiley +1 more source